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Vioxx - Rofecoxib - Dosage - Side Effects - Interactions - Warnings

Vioxx (rofecoxib) drug information, dosage, side effects, drug interactions, recall, and warnings. Vioxx, generic drug name rofecoxib, is/was a COX-2 selective inhibitor used treat the inflammation and pain of arthritis. On 09/30/2004, Merck the maker of Vioxx, issued a worldwide recall halting sales of the drug. Fallout from the Vioxx recall will continue for years to come.
  1. A - Z: Arthritis Drugs
  2. A - Z: Drug Costs
  3. A - Z: NSAIDs
  4. COX-2 Selective Inhibitors
  5. Inflammation
  6. Joint Pain
  7. Pain Relief

04/05/2006 Vioxx History: Jury Splits Decision In Last Two Cases Tried
04/05/2006, Two men, both of whom took Vioxx for more than 18 months, heard the verdict in their lawsuits against Merck. Analysts suggest this verdict will make it difficult for Merck to continue trying each case individually as they have said all along that they would do. There are now reportedly around 10,000 Vioxx lawsuits filed against Merck.

02/18/2006 Vioxx History: Merck Is Now Winning In Court 2-1
Merck has won the first federal lawsuit over recalled arthritis medication Vioxx. Merck is now winning in court 2-1. On 02/17/2006, a jury found Merck not reponsible for the death of a 53 year old man from Florida who suffered a heart attack after taking Vioxx for less than a month.

12/08/2005 Vioxx History: NEJM Says Merck Withheld Pertinent Details
12/08/2005, an editorial appearing in the NEJM (New England Journal of Medicine) claims Merck withheld pertinent data about Vioxx.

11/03/2005 Vioxx History: Merck Not Liable in Second Vioxx Case
11/03/2005, Merck, the maker of Vioxx, was found to be not liable by a New Jersey state jury for the 2001 heart attack of a man who had been taking Vioxx for two months prior to suffering the attack.

08/19/2005 Vioxx History: Merck Found Liable In First Vioxx Lawsuit
08/19/2005, Merck has been held liable in first Vioxx lawsuit, awarding plaintiff $253.4 million.

08/19/2005 POLL: Do You Agree With The First Vioxx Lawsuit Verdict?
08/19/2005, TAKE OUR POLL: The verdict of the first Vioxx lawsuit is in and Merck was held liable in the wrongful death case. Do you agree with the verdict or disagree with the verdict of the first Vioxx lawsuit?

08/19/2005 Vioxx History: Timeline For Vioxx From 1998 To 2005
08/19/2005, a rundown on the timeline for Vioxx from 1998 to 2005.

08/06/2005 Vioxx History: Vioxx Recall Fallout Still Being Felt
08/06/2005, fallout from the Vioxx recall is still being felt. The recall has impacted the U.S. Food and Drug Administration, Merck, and arthritis patients and doctors.

04/07/2005 FDA Announces Changes For All NSAIDs; Bextra Withdrawn
04/07/2005, Following scrutiny of the class of arthritis drugs known as NSAIDs and COX-2 inhibitors, the FDA has taken action.

04/07/2005 Q & A: FDA Actions On COX-2 Inhibitors & NSAIDs
04/07/2005, FDA announces planned regulatory actions for Bextra, Celebrex, and the non-selective prescription and over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs).

02/18/2005 COX-2 History: FDA Panel Votes On COX-2 Drugs
02/18/2005, FDA panel voted to keep Celebrex, Bextra, and Vioxx on the market. How close was the vote?

Vioxx Recalled by Merck Worldwide in 2004
Arthritis drug, Vioxx, was recalled worldwide by Merck.

02/18/2005 COX-2 History: COX-2 Inhibitors Being Scrutinized By FDA
02/18/2005, The U.S. Food and Drug Administration is deciding the risk versus benefit of COX-2 inhibitors.

09/08/2004 Vioxx History: Vioxx Approved By FDA For JRA
09/08/2004, Vioxx received approval from the FDA for the relief of the signs and symptoms of the most common forms of JRA (juvenile rheumatoid arthritis).

08/25/2004 Vioxx History: Evidence Links Vioxx To Heart Problems
08/25/2004, more evidence links Vioxx, expecially in high doses, to risk of heart problems, but Merck disagrees.

06/11/2003 Vioxx History: Vioxx Effective For Chronic Low Back Pain
06/11/2003, Study results indicated that Vioxx is safe and effective for the treatment of chronic low back pain, defined as back pain lasting three months or longer.

05/14/2001 Vioxx History: Second, Replicate Study Favors Celebrex
05/14/2001, study compares Celebrex and Vioxx and their cardiovascular side effects.

02/07/2001 Vioxx History: FDA Advised On Celebrex & Vioxx
02/07/2001, FDA Arthritis Advisory Committee met to review study results and to assess if either Celebrex or Vioxx should have warnings on their label reduced or any changes made to the prescribing information.

Celebrex And Vioxx Issue Rival Reports
06/22/2000, Pharmacia and Merck, the respective makers of Celebrex and Vioxx, both reported study results which claim their drug is the better choice.

12/28/1999 Vioxx History: Comparison Celebrex And Vioxx
12/28/1999, An overview of the similarities and differences between the COX-2 inhibitors Celebrex and Vioxx.

12/01/1999 Vioxx History: Reports Conflict On COX-2 Drug Safety
12/01/1999, Are the new COX-2 drugs really safer for the stomach than older NSAIDs?

05/27/1999 Vioxx History: Vioxx Approved By FDA
05/27/1999, Vioxx was approved by the FDA.

01/13/1999 Vioxx History: Celebrex And Vioxx Set To Battle
01/13/1999, Manufacturers of Celebrex and Vioxx are competing for the majority of the market trying out the new COX-2 inhibitors.

09/09/1998 Vioxx History: Studies Reveal Value Of Vioxx
09/09/1998, studies showed Vioxx provided significant improvement in osteoarthritis patients when assessing their ability to perform activities of daily life.

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