Drug Options
Although there is no cure for reactive arthritis, some treatments relieve symptoms of the disorder.
NSAIDs
Nonsteroidal anti-inflammatory drugs(NSAIDs) reduce joint inflammation and are commonly used to treat patients with reactive arthritis. Some NSAIDs are available without a prescription such as:
Other NSAIDs that are usually more effective for reactive arthritis must be prescribed by a doctor such as:
Corticosteroid Shots
For those with severe joint inflammation, injections of corticosteroids directly into the affected joint may reduce inflammation.
Topical Corticosteroids
These corticosteroids come in a cream or lotion and can be applied directly on the skin lesions, such as ulcers, associated with reactive arthritis. Topical corticosteroids reduce inflammation and promote healing.
Antibiotics
Antibiotics help eliminate bacterial infections that trigger reactive arthritis. The specific antibiotic prescribed depends on the type of bacterial infection present. Some doctors may recommend a person with reactive arthritis take antibiotics for a long period of time (up to 3 months). Research shows that in most cases, this practice is necessary.
Immunosuppressives / DMARDs
DMARDs such as methotrexate or sulfasalzine may help control severe symptoms that cannot be controlled by other drugs.
TNF Blockers
TNF blockers, such as etanercept and infliximab, may be effective for reactive arthritis and other spondyloarthropathies.

