Reactive Arthritis Research
Researchers continue to investigate the causes of reactive arthritis and study treatments for the condition. For example:
Researchers are trying to better understand the relationship between infection and reactive arthritis. In particular, they are trying to determine why an infection triggers arthritis and why some people who develop infections get reactive arthritis while others do not. Scientists also are studying why people with the genetic factor HLA-B27 are more at risk than others.
Researchers are developing methods to detect the location of the triggering bacteria in the body. Some scientists suspect that after the bacteria enter the body, they are transported to the joints, where they can remain in small amounts indefinitely.Researchers are testing combination treatments for reactive arthritis. In particular, they are testing the use of antibiotics in combination with TNF inhibitors and with other immunosuppressant medicines, such as methotrexate and sulfasalazine.
Related Resources - Reactive Arthritis
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)(www.niams.nih.gov)
- American College of Rheumatology (www.rheumatology.org)
- Arthritis Foundation (www.arthritis.org)
- Spondylitis Association of America (www.spondylitis.org)
Source: NIH Publication No. 02-5039
