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Related Resources - AmyloidosisArthritis Signs & SymptomsKidney Problems Diagnosed By Blood And Urine Tests Liver Blood Tests Related Resources - AmyloidosisPrimary AmyloidosisFamilial / Hereditary AmyloidosisSecondary Systemic Amyloidosis Related Resources - AmyloidosisCardiac AmyloidosisAmyloidosis on Fingers (image)Amyloidosis on Face (image) Related SitesWhat is Amyloidosis?About.com Health's Disease and Condition content is reviewed by Kate Grossman, MD
What is Amyloidosis?: Amyloidosis develops when specific proteins, known as amyloids, are abnormally deposited in the tissues and organs of the body. The deposited amyloids impair the function of organs, making the condition potentially fatal. Where Does Amyloid Develop?: Amyloid is produced by plasma cells (a type of immune cell) in the bone marrow. Amyloids can be deposited in any tissue or organ in the body. Types of Amyloidosis: Conditions Associated with Secondary Amyloidosis: Certain types of arthritis and related conditions may be associated with secondary amyloidosis including: Symptoms of Amyloidosis: The symptoms of amyloidosis are defined by the organs affected. Some symptoms associated with amyloidosis include:
Serious conditions can result from improperly functioning organs. Decreased heart function and kidney failure are just two of the possible complications. Diagnosing Amyloidosis: Definitive diagnosis is made by detecting amyloid in a biopsy specimen. A biopsy of the affected tissue or organ may be performed. Biopsy of skin including subcutaneous fat, rectal mucosa (inner lining of the rectum), or bone marrow may also help diagnose.
Other tests may include: Treating Amyloidosis: Primary amyloidosis may be treated with chemotherapy. Autologous stem cell transplantation is another possible treatment. Secondary amyloidosis may be helped by aggressive treatment of the underlying condition. Organs affected should be treated as well. What Does the Future Hold for Patients with Amyloidosis?: Amyloidosis cannot be prevented and cannot be cured. As stated, the course of amyloidosis depends on what organs are affected. If the heart and kidney are affected, organ failure and death are possible. Organ involvement may result in death within 1 to 3 years. Related Resources: Sources: Amyloidosis, MayoClinic.com; Amyloidosis, MedicineNet; Primary Amyloidosis, MedlinePlus; Secondary Systemic Amyloidosis, ADAM Updated: August 26, 2006 Related Resources - AmyloidosisArthritis Signs & SymptomsKidney Problems Diagnosed By Blood And Urine Tests Liver Blood Tests Related Resources - AmyloidosisPrimary AmyloidosisFamilial / Hereditary AmyloidosisSecondary Systemic Amyloidosis Related Resources - AmyloidosisCardiac AmyloidosisAmyloidosis on Fingers (image)Amyloidosis on Face (image) |
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