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Methotrexate, classified as a DMARD (disease-modifying anti-rheumatic drug), is considered the gold standard treatment for rheumatoid arthritis.
  1. A - Z: Arthritis Drugs
  2. A - Z: Lower Drug Costs
  3. DMARDs
  4. Folic Acid (Folate)
  5. Needlephobia Overview

Is Methotrexate Used to Treat Rheumatoid Arthritis Considered Chemotherapy?
Methotrexate is a drug that is used to treat cancer (chemotherapy). In lower doses, methotrexate is a disease-modifying anti-rheumatic drug (DMARD).

Methotrexate and Pregnancy
Is it safe for women to take methotrexate while pregnant? Is the drug safe for men and women who are planning a family?

Methotrexate and Folic Acid - What's the Optimal Regimen?
Typically, arthritis patients taking methotrexate are also prescribed folic acid. Some patients take folic acid daily while others skip it on methotrexate day. Which is right?

Methotrexate Quiz
Methotrexate is considered the gold standard treatment for rheumatoid arthritis. How much do you know about methotrexate? Take our Methotrexate Quiz.

Methotrexate - 10 Things You Should Know
Methotrexate is disease-modifying anti-rheumatic drug (DMARD) used to treat certain types of rheumatic conditions.

Is Methotrexate Injection Better Than Oral Methotrexate?
Methotrexate injection is an alternative to oral administration of the drug. Methotrexate injection is preferred by some patients. Is methotrexate injection as effective as oral methotrexate?

Facts About Methotrexate
Methotrexate is a disease-modifying anti-rheumatic drug used to treat rheumatoid arthritis and some other rheumatic diseases.

Methotrexate for Rheumatoid Arthritis
Methotrexate, a disease-modifying anti-rheumatic drug, is commonly used to treat rheumatoid arthritis.

What Are Cytotoxic Drugs?
Cytotoxic drugs, such as methotrexate, Cytoxan, and Imuran are used to treat rheumatoid arthritis and some other rheumatic diseases. There are potentially serious side effects associated with these drugs, but methotrexate appears to have the best safety profile. Learn more about cytotoxic drugs.

Second Course Of Methotrexate May Be Effective
Rheumatoid arthritis patients who have not responded to their first course of methotrexate, especially if the first course was a low-dose (10 mg or less per week), may still derive benefit from a second course of methotrexate.

Drug-induced hepatitis from methotrexate
Methotrexate is listed among "other problem drugs for the liver". (Illustrated)

Combination Treatment for Rheumatoid Arthritis
Dr. Isadore Rosenfeld offers information about what's the latest arthritis treatment, including the benefit of combination therapy.

Humira And Methotrexate In Combination Better Than Either Drug Alone
Results from the PREMIER study reveal that for adults with early, aggressive rheumatoid arthritis, treatment with Humira and methotrexate in combination is more effective than either drug alone.

Methotrexate: Incorrect dosing can cause serious harm
Britain's National Patient Safety Agency (NPSA) has stated that oral methotrexate tablets are safe and effective if taken at the right frequency and the right dose. The drug is normally taken weekly, not daily. Confusion over the correct dosing schedule can cause serious harm.

What Causes And Heals Mouth Sores?
Mouth sores are not uncommon in arthritis patients, especially those treated with methotrexate.

What can people do who suffer hair loss from drugs like methotrexate and Arava?
Hair loss is an unwanted side effect of some arthritis drugs, such as methotrexate and Arava.

A - Z: Drug Side Effects
A - Z: Drug Side Effects

Megaloblastic anemia
Megaloblastic anemia is a blood disorder characterized by anemia, with red blood cells that are larger than normal. Deficiencies of vitamin B-12 and folic acid are the most common causes, others causes are certain hereditary disorders and drugs that affect DNA synthesis such as chemotherapy agents (methotrexate).

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