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Milnacipran - Midalcipran - Ixel - Fibromyalgia Drug Development

Milnacipran, also known as Ixel and Midalcipran, is a medication in development as a drug treatment option for fibromyalgia. Milnacipran is being developed by Cypress Bioscience. Milnacipran is in the class of antidepressants known as norepinephrine serotonin reuptake inhibitors.
Development Status: Milnacipran
Cypress is developing milnacipran for the treatment of fibromyalgia syndrome (FMS). Milnacipran is the first of a new class of agents known as norepinephrine serotonin reuptake inhibitors, or NSRIs, which increase the level of norepinephrine more than they do serotonin, from Cypress BioScience.
Milnacipran: Results of First Phase III Trial
While the results in our first Phase III trial did not achieve a p-value of less than or equal to 0.05, we believe the results support continued development of milnacipran as a treatment for FMS. The ongoing development program for milnacipran includes an ongoing second Phase III study and an additional third Phase III study, from Cypress Bioscience.
Milnacipran From Wikipedia
In experimental studies Milnacipran showed useful activity as adjunct in the therapy of Fibromyalgia and Lupus, both conditions with potentially devastating effects. In January 2006, Forest Pharmaceuticals and Cypress Bioscience agreed to commence a phase III multicenter study encompassing 1,200 patients with Fibromyalgia. Early results will be available by mid 2007, from Wikipedia.
Fibromyalgia Medication Options - How Is Fibromyalgia Treated?
There are no medications approved by the FDA for treating fibromyalgia, although a few such drugs are in development. Doctors treat fibromyalgia with a variety of medications developed and approved for other purposes.
Fibromyalgia Screening Quiz
Fibromyalgia is difficult to diagnose. Combinations of symptoms can occur which overlap with other autoimmune diseases. There are symptoms which are considered "defining" of fibromyalgia. There are also symptoms considered "non-defining" but they often occur as part of fibromyalgia syndrome.
Fibromyalgia - Test Your Knowledge
Fibromyalgia is often regarded as a medical enigma. Symptoms of fibromyalgia syndrome can overlap with other conditions making it difficult to diagnose. How much do you know about fibromyalgia?
The Fibromyalgia Guide - Free Newsletter E-Course
Fibromyalgia is a condition characterized by body aches, pain, sleep problems, extreme fatigue, depression and anxiety, in combination with tenderness of specific areas (muscles and tender points) on the body. Learn more about fibromyalgia by signing up for our free newsletter e-course.
Milnacipran For Fibromyalgia
Milnacipran (also known as Ixel and Midalcipran) is the first in a new class of antidepressants known as Norepinephrine Serotonin Reuptake Inhibitors (or NSRI's). Unlike Prozac or Effexor, milnacipran regulates norepinephrine and serotonin equally in order to alleviate chronic pain more effectively, from Creaky Joints.
08/03/2004 Off-Label Treatments, New Drugs Target Fibromyalgia
08/03/2004, Cypress Bioscience is the closest to getting the first drug approved for fibromyalgia. The company has worked intensely with the FDA to craft the clinical trials, and is in the final stage of testing of its drug, milnacipran. Cypress hopes to file for FDA approval during 2006, from ImmuneSupport.com.

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