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Guide to Juvenile Rheumatoid Arthritis (JRA)

By Carol & Richard Eustice, About.com

Updated: February 26, 2007

About.com Health's Disease and Condition content is reviewed by Kate Grossman, MD

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Part 2 of 10 - What is Pauciarticular Juvenile Rheumatoid Arthritis?

Pauciarticular Juvenile Rheumatoid Arthritis

Pauciarticular Juvenile Rheumatoid Arthritis: Pauciarticular means that four or fewer joints are affected. Pauciarticular is the most common form of juvenile rheumatoid arthritis; about half of all children with juvenile rheumatoid arthritis have this type.

  • Pauciarticular juvenile rheumatoid arthritis typically affects large joints, such as the knees.
  • Girls under age 8 are most likely to develop this type of juvenile rheumatoid arthritis.

    Antibodies

    Some children have special kinds of antibodies in the blood. One is called antinuclear antibody (ANA) and one is called rheumatoid factor.

  • What is ANA (Antinuclear Antibody)?
  • What is Rheumatoid Factor?
  • Eye Problems

    Eye disease affects about 20 to 30 percent of children with pauciarticular juvenile rheumatoid arthritis. Up to 80 percent of those with eye disease also test positive for ANA and the disease tends to develop at a particularly early age in these children. Regular examinations by an ophthalmologist (a doctor who specializes in eye diseases) are necessary to prevent serious eye problems such as iritis (inflammation of the iris, the colored part of the eye) or uveitis (inflammation of the uvea, or the inner eye).

    Prognosis

    Some children with pauciarticular disease outgrow arthritis by adulthood, although eye problems can continue and joint symptoms may recur in some people.

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