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What Is Polyarticular JRA?

By , About.com Guide

Updated April 22, 2013

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Definition: Polyarticular JRA refers to a form of juvenile rheumatoid arthritis that affects five or more joints. Polyarticular JRA is the type of juvenile arthritis doctors consider to be most similar to adult rheumatoid arthritis. About 30% of all children with JRA have polyarticular disease. Girls are two times more likely to have this disease than boys.

The joints are usually affected symmetrically (on both sides) in polyarticular JRA. Often, the small joints of the hands are affected, as well as other joints. Low grade fever, weight loss, and anemia may occur, and in severe cases growth problems. Most children with polyarticular disease test negative for rheumatoid factor and their prognosis is usually good with treatment. Fewer of the children with polyartiular JRA test positive for rheumatoid factor and are at higher risk for chronic, progressive destruction of joints.

Sources:

Primer on the Rheumatic Diseases. Arthritis Foundation. Thirteenth edition.

Pronunciation: polly-art-ik-u-lar
Also Known As: JRA
Examples:
The child was diagnosed with polyarticular JRA.

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