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What is Systemic?

By , About.com Guide

Updated November 17, 2006

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: Systemic means pertaining to or affecting the whole body rather than localized. Systemic diseases or systemic illnesses affect the entire body as opposed to a single organ or body part.

Some systemic forms of arthritis include:

  • lupus (short name for systemic lupus erythematosus or SLE)
  • scleroderma (systemic sclerosis)
  • rheumatoid arthritis
  • Osteoarthritis (the most common type of arthritis) is not considered a systemic form of arthritis.

    Also Known As: somatic
    Common Misspellings: sistemic
    Examples:
    Lupus is a systemic disease.

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