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Study: Cymbalta Decreases Pain in Fibromyalgia Patients
Study results indicate that fibromyalgia patients treated with Cymbalta (duloxetine) experienced greater reduction in pain severity one week after starting the medication compared to patients receiving placebo. At 3 and 6 months, patients on Cymbalta also showed improvement in how they felt overall since starting the medication when compared to placebo.

Drug Monograph: Cymbalta / Duloxetine
Duloxetine is an oral antidepressant that is similar in action to the antidepressants clomipramine and venlafaxine; like venlafaxine, the drug belongs to the Serotonin-Norepinephrine Reuptake Inhibitor class. Like venlafaxine, duloxetine inhibits the reuptake of both serotonin and norepinephrine and is often referred to as a 'dual' inhibitor.

Patient Education: Cymbalta / Duloxetine Capsules
Patient education for Cymbalta / duloxetine capsules.

Product Photographs: Cymbalta / Duloxetine Capsules
Product photographs of Cymbalta / duloxetine capsules.

Fibromyalgia Medication Options - How Is Fibromyalgia Treated?
There are no medications approved by the FDA for treating fibromyalgia, although a few such drugs are in development. Doctors treat fibromyalgia with a variety of medications developed and approved for other purposes.

Cymbalta Effective For Women With Fibromyalgia, But Not Men
Cymbalta (duloxetine) has been approved by the FDA. Cymbalta targets two chemical messengers in the body, serotonin and norepinephrine. According to a report in the journal Arthritis & Rheumatism, Cymbalta seems to be effective in treating the symptoms associated with fibromyalgia in women, but not in men.

Fibromyalgia Screening Quiz
Fibromyalgia is difficult to diagnose. Combinations of symptoms can occur which overlap with other autoimmune diseases. There are symptoms which are considered "defining" of fibromyalgia. There are also symptoms considered "non-defining" but they often occur as part of fibromyalgia syndrome.

Fibromyalgia - Test Your Knowledge
Fibromyalgia is often regarded as a medical enigma. Symptoms of fibromyalgia syndrome can overlap with other conditions making it difficult to diagnose. How much do you know about fibromyalgia?

The Fibromyalgia Guide - Free Newsletter E-Course
Fibromyalgia is a condition characterized by body aches, pain, sleep problems, extreme fatigue, depression and anxiety, in combination with tenderness of specific areas (muscles and tender points) on the body. Learn more about fibromyalgia by signing up for our free newsletter e-course.

Drug Profile: Cymbalta (duloxetine hydrochloride)
Cymbalta (duloxetine hydrochloride) is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) for oral administration.

The Cymbalta Homepage
Information on Cymbalta (Duloxetine), from Eli Lilly and Company.

Off-Label Treatments, New Drugs Target Fibromyalgia
Eli Lilly has shown in early studies that the antidepressant Cymbalta alleviates pain associated with fibromyalgia. The new drug is thought to work better in pain than the most widely used class of antidepressants, which affect serotonin in the brain. Cymbalta affects different brain chemicals, norepinephrine and dopamine, from ChronicFatigueSupport.

CenterWatch Newly Approved Drug Therapies: Cymbalta (Duloxetine)
Cymbalta (duloxetine hydrochloride) is a oral dual reuptake inhibitor that enhances the levels of the neurotransmitters, serotonin and norepinephrine, which are involved in depression, from Centerwatch.