COX-2 Inhibitors - Dosage - Side Effects - Interactions - Warnings
COX-2 selective inhibitor drug information, dosage, side effects, drug interactions, recalls, and warnings. COX-2 selective inhibitors are a subset of the NSAIDs (nonsteroidal anti-inflammatory drugs) that are used to treat the pain and inflammation of arthritis.
Cyclooxygenase (COX) is an enzyme that is responsible for the formation of prostanoids. The three main groups of prostanoids -- prostaglandins, prostacyclins, and thromboxanes -- are each involved in the inflammatory response. There are two, if not three, known types of cyclooxygenase (COX-1, COX-2, and COX-3).
A brief explanation and fast facts about the COX-2 inhibitors.
04/07/2005, Following scrutiny of the class of arthritis drugs known as NSAIDs and COX-2 inhibitors, the FDA has taken action.
04/07/2005, FDA announces planned regulatory actions for Bextra, Celebrex, and the non-selective prescription and over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs).
One of the mainstays of arthritis treatment has been medications in the class known as the nonsteroidal anti-inflammatory drugs or NSAIDs. In 1999, a new type of medication, called COX-2 selective NSAIDs, was introduced to treat the pain and inflammation associated with arthritis, from ACR.