COX-2 Inhibitors - Dosage - Side Effects - Interactions - Warnings
- A - Z: Arthritis Drugs
- A - Z: Drug Costs
- A - Z: Joint Pain
- A - Z: NSAIDs
- A - Z: Pain Relief
- Arcoxia (Etoricoxib) (14)
- Bextra (Valdecoxib) (15)
- Celebrex (Celecoxib) (25)
- Licofelone (Dual COX/LOX) (10)
- Prexige (Lumiracoxib) (10)
- Vioxx (Rofecoxib) (31)
Cyclooxygenase: COX-1 and COX-2 Explained
Cyclooxygenase (COX) is an enzyme that is responsible for the formation of prostanoids. The three main groups of prostanoids -- prostaglandins, prostacyclins, and thromboxanes -- are each involved in the inflammatory response. There are two, if not three, known types of cyclooxygenase (COX-1, COX-2, and COX-3).
What Are COX-2 Inhibitors?
COX-2 inhibitors are among the medications used to treat arthritis.
Celecoxib Approved by FDA - Generic for Celebrex
Celecoxib, the generic for Celebrex, was approved by the FDA in 2014. Celebrex was approved for osteoarthritis and rheumatoid arthritis in 1998.
04/07/2005 FDA Announces Changes For All NSAIDs; Bextra Withdrawn
04/07/2005, Following scrutiny of the class of arthritis drugs known as NSAIDs and COX-2 inhibitors, the FDA has taken action.
04/07/2005 Q & A: FDA Actions On COX-2 Inhibitors & NSAIDs
04/07/2005, FDA announces planned regulatory actions for Bextra, Celebrex, and the non-selective prescription and over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs).
ACR Patient Education: NSAIDs / COX-2 Selective NSAIDs
One of the mainstays of arthritis treatment has been medications in the class known as the nonsteroidal anti-inflammatory drugs or NSAIDs. In 1999, a new type of medication, called COX-2 selective NSAIDs, was introduced to treat the pain and inflammation associated with arthritis, from ACR.