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COX-2 Inhibitors - Dosage - Side Effects - Interactions - Warnings

COX-2 selective inhibitor drug information, dosage, side effects, drug interactions, recalls, and warnings. COX-2 selective inhibitors are a subset of the NSAIDs (nonsteroidal anti-inflammatory drugs) that are used to treat the pain and inflammation of arthritis.
  1. A - Z: Arthritis Drugs
  2. A - Z: Drug Costs
  3. A - Z: Joint Pain
  4. A - Z: NSAIDs
  5. A - Z: Pain Relief
  6. Arcoxia (Etoricoxib) (14)
  7. Bextra (Valdecoxib) (15)
  8. Celebrex (Celecoxib) (25)
  9. Licofelone (Dual COX/LOX) (10)
  10. Prexige (Lumiracoxib) (10)
  11. Vioxx (Rofecoxib) (31)

Cyclooxygenase: COX-1 and COX-2 Explained
Cyclooxygenase (COX) is an enzyme that is responsible for the formation of prostanoids. The three main groups of prostanoids -- prostaglandins, prostacyclins, and thromboxanes -- are each involved in the inflammatory response. There are two, if not three, known types of cyclooxygenase (COX-1, COX-2, and COX-3).

What Are COX-2 Inhibitors?
COX-2 inhibitors are among the medications used to treat arthritis.

Celecoxib Approved by FDA - Generic for Celebrex
Celecoxib, the generic for Celebrex, was approved by the FDA in 2014. Celebrex was approved for osteoarthritis and rheumatoid arthritis in 1998.

04/07/2005 FDA Announces Changes For All NSAIDs; Bextra Withdrawn
04/07/2005, Following scrutiny of the class of arthritis drugs known as NSAIDs and COX-2 inhibitors, the FDA has taken action.

04/07/2005 Q & A: FDA Actions On COX-2 Inhibitors & NSAIDs
04/07/2005, FDA announces planned regulatory actions for Bextra, Celebrex, and the non-selective prescription and over-the-counter (OTC) non-steroidal anti-inflammatory drugs (NSAIDs).

ACR Patient Education: NSAIDs / COX-2 Selective NSAIDs
One of the mainstays of arthritis treatment has been medications in the class known as the nonsteroidal anti-inflammatory drugs or NSAIDs. In 1999, a new type of medication, called COX-2 selective NSAIDs, was introduced to treat the pain and inflammation associated with arthritis, from ACR.

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