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What Is Behçet's Disease? (Behcet's Disease)

By Carol & Richard Eustice, About.com

Updated June 15, 2006

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Definition: Behçet's disease is an autoimmune disease that results from damage to blood vessels throughout the body, particularly veins. In an autoimmune disease, the immune system attacks and harms the body's own tissues.

The exact cause is unknown. It is believed that an autoimmune reaction may cause blood vessels to become inflamed, but it is not clear what triggers this reaction.

Behçet's disease affects each person differently. The four most common symptoms are mouth sores, genital sores, inflammation inside of the eye, and skin problems. Inflammation inside of the eye (uveitis, retinitis, and iritis) occurs in more that half of those with Behçet's disease and can cause blurred vision, pain, and redness. Other symptoms may include arthritis, blood clots, and inflammation in the central nervous system and digestive organs.

There is no cure for Behçet's disease. Treatment typically focuses on reducing discomfort and preventing serious complications. Corticosteroids and other medications that suppress the immune system may be prescribed to treat inflammation.

Behçet's is a chronic disease that recurs. However, patients may have periods of time when symptoms go away temporarily (remission). How severe the disease is varies from patient to patient. Some patients may live normal lives, but others may become blind or severely disabled.

Related Resources

  • Behçet’s Disease / Behcet's Disease
  • Guide To Behçet’s Disease (Behcet's Disease)
  • Temporal Arteritis
  • Pronunciation: BAY-SETS
    Also Known As: Adamantiades
    Alternate Spellings: Bechets Disease
    Common Misspellings: Behcet's Disease
    Examples:
    Behçet's disease was first described in 1937 by Dr. Hulusi Behçet, a dermatologist in Turkey.

    Why does "Behçet" contain a cedilla mark? According to Wikipedia, "cedilla is a hook (ç) added under certain consonant letters as a diacritic mark to modify their pronunciation."

    Source: Behçet's Disease of the Eye (edited), National Eye Institute, National Institutes of Health, April 2005

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