B-Cell Depletion Therapy - B-Lymphocyte Depletion Therapy Information
In late 2000, media reports hyped B-lymphocyte (b-cell) depletion therapy as a "cure" for rheumatoid arthritis. Although certainly not a cure, b-cell depletion therapy with a combination of the drugs rituximab, cyclophosphamide, and prednisolone showed promise as an arthritis treatment option. Research on b-cell depletion therapy is ongoing.
A brief explanation and fast facts about antibodies.
A brief explanation and fast facts about B-cells.
03/01/2006, Rituxan, the world's best-selling cancer drug, has been FDA approved to be used in combination with methotrexate to treat rheumatoid arthritis by reducing the signs and symptoms in adult patients who have moderately-to-severely active rheumatoid arthritis and have failed one or more anti-TNF drugs e.g. Enbrel (etanercept), Remicade (infliximab), or Humira (adalimumab).
06/13/2005, B cell depletion therapy is now in trials for a number of autoimmune conditions. In many of these conditions major improvement has been seen in a good proportion of cases in pilot studies, particularly in rheumatoid arthritis, lupus, dermatomyositis, autoimmune neuropathies, immune thrombocytopenic purpura and haemolytic anaemia, from University College London.
06/01/2001, News of exciting research developments and a potential cure for rheumatoid arthritis was splashed everywhere last November. There has been an eerie silence about it ever since. Professor Jonathan CW Edwards lets us know where things stand.
11/20/2000, Were the recent reports which hyped B-lymphocyte depletion therapy as a potential cure for rheumatoid arthritis accurate or were the reports irresponsible journalism?
11/01/2000, Researchers from University College in London have presented findings from an experimental new rheumatoid arthritis treatment which involves B-lymphocyte depletion. Some say it's a "cure", others say a "remission", but everyone agrees it's exciting.
Professor Jonathan Edwards, Dr. Jo Cambridge, Dr. Vikki Abrahams, Dr. Maria Leandro: Arthritis research and information website at University College London.
11/20/2000, A number of high-profile media reports heralded a study on B-lymphocyte depletion as a possible cure for rheumatoid arthritis. Many patients and physicians have understandably expressed interest in the therapy, from ACR Hotline.
10/29/2000, A new arthritis treatment by British scientists may lead to a cure. Initial trials of the drug treatment have exceeded all expectations with only two out of 20 patients showing no benefits, from BBC News.
