To weigh benefits and risks, you and your doctor need to discuss common side effects and possible serious adverse reactions. Certain details should be considered, including:
- severity of arthritis
- present quality of life
- other medical conditions/allergies
- projected ability to tolerate the treatment
- ways to minimize potential side effects
- risk of going without treatment
When all is considered, the potential benefits should outweigh the possible risks if you're to go forward with treatment.
Benefits Versus Risks. Adverse Drug Reactions. Merck Manual Home Edition. August 2007.