If you have seen the words entheses, enthesitis or enthesopathy in your x-ray or medical reports, you may have been unclear about their meaning.
- What is enthesitis?
- What are the symptoms?
- How is enthesitis treated?
- Is enthesitis more common with certain types of arthritis?
What Is Enthesopathy?
Enthesopathy is a condition that affects the entheses (e.g. inflammation of the entheses). The entheses are sites of tendinous or ligamentous attachment to the bone. Enthesopathy may be due to an inflammatory condition such as psoriatic arthritis or a condition due to injury or overload such as plantar fasciitis.
Conditions Associated With Enthesitis
Among others, conditions associated with enthesitis include:
- Achilles tendinitis
- reactive arthritis
- rheumatoid arthritis
- osteoarthritis
- diffuse idiopathic skeletal hyperostosis (DISH)
Symptoms Associated With Enthesitis
Symptoms include pain and often swelling. In addition to pain and swelling of the heel, other commonly affected areas include the toes and fingers, which can look like a sausage caused by swelling at the entheses. With enthesitis, the elbow, pelvis and chest wall may also have pain and/or swelling.
Treatment of Enthesitis
Treatment of enthesitis is based on the underlying condition. For example, if enthesitis is due to an inflammatory condition such as psoriatic arthritis, treatment may include:
- nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g. ibuprofen, naproxen)
- methotrexate
- TNF blockers (e.g. Enbrel, Remicade, and Humira)
For plantar fasciitis unrelated to an inflammatory condition, heel inserts and NSAIDs are used.
Dr. Zashin is clinical assistant professor at University of Texas Southwestern Medical School and an attending physician at Presbyterian Hospitals of Dallas and Plano. Dr. Zashin is author of Arthritis Without Pain - The Miracle Of TNF Blockers. The book is useful for anyone on one of the biologic drugs or considering the biologic drugs.

