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What Are Rheumatoid Nodules?

Appearance and Significance of Rheumatoid Nodules

By , About.com Guide

Updated October 15, 2012

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Description of Rheumatoid Nodules

As part of the rheumatoid process, firm, non-tender, subcutaneous nodules develop in about 25% of rheumatoid arthritis patients. These are commonly found at pressure points like the elbow, back of the forearm, and metacarpophalangeal joint. Nodules usually occur in chronic, active cases of rheumatoid arthritis, and are commonly associated with more joint deformity and serious extra-articular manifestations including lungs, eyes, and blood vessels. Nodules may vary in size during the course of the disease process.

Complications of Rheumatoid Nodules

Johns Hopkins claims complications of rheumatoid nodules include:

  • pain
  • limited joint mobility
  • neuropathy
  • ulceration
  • fistula formation
  • infection

Surgical removal is an option, but nodules tend to recur in as little as a few months when they are present over an area of repeated trauma. Intranodular steroid injections may reduce the size of the nodule.

Photos of Actual Rheumatoid Nodules

  • Arthritis Hand Photo Gallery
    Hand damage and deformity caused by arthritis can include nodules, swelling, stiffness, ulnar drift, contractures, and other problems. Photos of hands damaged by arthritis.

Sources:

Interview with Raymond Federman, M.D. (rheumatologist)

Case rounds. Case report #6 by Andrea Marx, M.D., The Johns Hopkins University.

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