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By Carol & Richard Eustice, About.com Guides to Arthritis since 1997

Cartilage: Researchers Reveal Information About Structure

Tuesday January 16, 2007
Cartilage which covers the ends of bones allowing for the smooth, gliding movement at the joints is known as articular cartilage. In osteoarthritis, the cartilage wears away and causes pain and limited range of motion. Researchers have long been studying the structure of cartilage with the hope of improving arthritis treatment options.

It is well-known that cartilage is composed of interlocking collagen fibers which give it structure and strength. The exact structure of the fibers however, also referred to as fibrils, has remained elusive for decades. Using electron microscopic techniques, researchers from the University of Manchester have discovered the molecular structure of the thinner of two types of collagen fibrils. The findings are considered important to determining what occurs at the molecular level as osteoarthritis develops.

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