It is known that rheumatoid arthritis is associated with an increased risk of cardiovascular disease and mortality. Researchers measured anti-CCP, rheumatoid factor, ANA, and the use of DMARDs in nearly 10,000 postmenopausal women over a 10-year period to evaluate any correlation to mortality.
According to Arthritis and Rheumatology, of the study participants, anti-CCP-positive patients had a substantially greater risk of mortality that could not otherwise be explained by age, positive rheumatoid factor, positive antinuclear antibodies, or DMARD use.
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