According to study results in the September 25, 2013 issue of JAMA (the Journal of the American Medical Association), among overweight and obese adult patients with knee osteoarthritis, the combination of intensive diet and exercise was associated with less knee pain and improved function after 18 months compared to diet alone or exercise alone. Results revealed that average weight loss was greater in the diet/exercise group and the diet alone group compared to the exercise alone group. The diet/exercise group also had faster walking speed, and better physical health-related quality of life compared to the exercise group.
Also, participants in the diet/exercise group and the diet group had greater reductions in interleukin-6 levels (related to inflammation) than the exercise group. The diet group had greater reductions in knee compressive force (joint load) than those in the exercise group, too.
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