Researchers assessed the effectiveness of lateral wedge insoles as a treatment for pain associated with medial knee osteoarthritis. A meta-analysis that included 12 randomized clinical trials involving 885 study participants, 502 of whom had received treatment with lateral wedge insoles, was performed.
According to study results published August 21, 2013 in the Journal of the American Medical Association, pooling of the meta-analysis data revealed a statistically significant association between lateral wedge insoles and reduced pain in medial knee osteoarthritis. However, limiting studies to those that used a neutral insole as the control (i.e., comparison) did not reveal a clinically significant result for lateral wedge insoles. Researchers concluded that the findings do not support the use of lateral wedge insoles as a conservative treatment for medial knee osteoarthritis.
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