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Carol Eustice

How Should Arthritis Patients Take Methotrexate and Folic Acid?

By July 30, 2013

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During my nearly 39 years of having rheumatoid arthritis, I have been on and off of methotrexate. In the early years, I was prescribed methotrexate. At some point, I discontinued the drug, but years later when I was prescribed Remicade, methotrexate was added back. Whenever I was taking methotrexate, I was also prescribed 1 mg. folic acid to be taken daily. I assumed that's what all methotrexate patients were prescribed.

Not until recently, while talking to my cousin who also has rheumatoid arthritis, did I discover not everyone on methotrexate is taking folic acid according to the same schedule. Who knew? My cousin was told not to take it on the day of the week she takes her methotrexate, while as I said, I have always been prescribed folic acid to be taken daily. I did some internet research and asked a couple of rheumatologists about standard protocol for methotrexate and folic acid. See what I learned in Methotrexate and Folic Acid - What's the Optimal Regimen?

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