It's not a new treatment option. Sulfasalazine (brand name Azulfidine) has been around for about 60 years. However, its use for rheumatoid arthritis has only increased within the last 20 years or so. When biologic drugs were first marketed in 1998, you didn't hear as much about sulfasalazine. But now, we're hearing more about sulfasalazine again, especially for patients who cannot use methotrexate or who are unsuitable candidates for biologic drugs.
In fact, in June I blogged about a report in the New England Journal of Medicine which revealed that an older, conventional treatment regimen was just as effective as newer biologic drugs in rheumatoid arthritis patients who did not respond well to methotrexate alone. The older regimen was a combination of three disease-modifying anti-rheumatic drugs (DMARDs) -- methotrexate, sulfasalazine, and hydroxychloroquine. Learn more about sulfasalazine in Sulfasalazine - What You Need to Know.
- Methotrexate - 10 Things You Should Know
- Plaquenil (hydroxychloroquine) - What You Should Know
- Facts About DMARDs
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