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Carol Eustice

Do Chronic Pain Patients Need Zohydro?

By January 3, 2012

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Several drug companies are developing a more potent pain medication containing hydrocodone. The new drug would contain up to 10 times the amount of hydrocodone that is found in drugs currently available, such as Vicodin. One of the drug companies, Zogenix, plans to apply for FDA approval of its timed-released version, known as Zohydro, this year and have it on the market in 2013. The possible addition of Zohydro to painkilling options has brought forward proponents and opponents.

Proponents say Zohydro will present doctors with another option for treating chronic pain patients, since not all medications are equally effective for all patients. It also has been suggested that a pure hydrocodone medication eliminates problems associated with analgesics that have acetaminophen as part of their composition. Acetaminophen overdose has been linked to potentially fatal liver toxicity. Zohydro will be closely monitored and you will be required to visit your doctor each time you need more pills, unlike current hydrocodone-acetaminophen medications that permit 5 refills.

Opponents believe Zohydro will provide the same abuse potential as OxyContin did, when crushing the timed-release pills produced an intense high. The maker of OxyContin reformulated the medication to make it more tamper-proof. With Zohydro, are drugmakers just reinventing an old problem? Does any of this make sense to arthritis patients who are still angry at the FDA for taking Darvocet off the market in November 2010? Share your thoughts below.

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Photo by Keith Webber Jr. (iStockphoto)

Comments
January 4, 2012 at 4:17 pm
(1) simplymarvi says:

As a person with chronic pain, I relish the idea of new pain med options. It seems plausible that Zohydro could be formulated the same way Oxycontin is; to be tamper resistant. It is my hope the companies will do this. The potential risks of liver problems scare me, as well as the risk of addiction.

Oxycontin takes the edge off of my pain most of the time. If I have sinus or tooth pain, it doesn’t touch it. Hydrocodone does, but it is hard to get that while on the Oxy. So, I still suffer in other areas.

*Lupus (SLE), SJogrens Syndrome, lumbar facet arthritis, lumbar and cervical stenosis and disk bulges.

January 4, 2012 at 5:09 pm
(2) Sooz5555 says:

Well, again we have to hear about drugs that may help us, only to have it snatched out of grasp due to the minority of abusers whose actions deny us the pain relief we need. Those of us with arthritis who follow directions and take our medications responsibly are penalized because of a minority of people. How about caring more for the pain victim and less about the pain med abuser for a change?

January 4, 2012 at 10:15 pm
(3) JoVon says:

I would like to have a pain med that doesn’t require acetominophine as it can cause liver failure. I have RA and pinched nerves in my back and am in chronic pain. I am very careful in how I take my meds because I am afraid of addiction. Only a few bad apples spoil it for the rest of us who have a real need for pain relief and take steps to keep from becoming addicted.

January 4, 2012 at 10:33 pm
(4) Judith says:

Sooz is absolutely right on. There has been this huge fear brainwashed
into the public, probably by BigPharma, that all will be addicts.
I`m 53 and have had chronic spinal osteoarthritis for 3 years. My doctor
of 12 years gave me Utram(tramadol) and Mobic(meloxicam) to try.
The side effects are mind-boggling and extremely dangerous. Then
she suggested Darvocet, 2 weeks later the FDA banned it.
So what`s left? Nsaids(ibuprofen) that tears up your digestion system or Acetaminophen(tylenol) which eats up your liver, kidney and pancreas.
If you do some research on the narcotics(opiates) there are hardly
any side effects. There are low dosage hydrocodones but take note
that some are combined w/ enormous amounts of acetaminophen.
Most of us made it through our younger years, the drug years and didn`t turn into addicts. I`m in so much pain I can`t function. The only time I had some relief was when I was given medication for dental
surgery. I have recently changed doctors and she gave me Valium
5mgs.(diazepam) twice a day, which not only helps the anxiety and
depression but also lessens the muscle spasms. My other doctor
said oh no, much to addictive but it was okay for her to give me Xanax
for sleep. Crazy! I am now waiting on going to a pain management
clinic. I can`t make this stuff up, the X-rays speak for themselves.
There are so many in needless pain due to the abuse of a few.
BigPharma is winning out for the almighty dollar instead of healing.
I SAY GO ZOHYDRO. Life is too short to suffer in agony. Thanks.

January 5, 2012 at 2:35 pm
(5) Lisa says:

Ok now, this scare smear that is being put out there in the media regarding this “new drug” Zohydro should stop. It is not truth…..the people who sell Tylenol are going to loose big money by no longer having the monopoly on piggybacking their chemicals on the opiates so many have to use for chronic pain. It makes perfect sense to offer a no Tylenol choice. In fact there always has been an opiate that does not contain the Tylenol, ( available at a really high cost.) There is an opiate/ibuprofen choice as well, but you do not hear much about that one either do you? My question is this….why can’t they just make the Norco, Vicodin, or whatever opiate works for you, without the Tylenol… period? Plain and simple, same dosage of opiate WITHOUT Tylenol? Why does it have to be “so strong” it requires a triplicate script and a monthly Dr. visit??? THIS IS JUST PLAIN STUPID The removal of a harmful adjuvant from a proven opiate is not rocket science nor is it scary. The medication should cost less to make! We can see though the farce Big Pharm!!!

January 6, 2012 at 1:15 am
(6) Ruby says:

You know, when I first read the article tonight about the new cronic pain medicine Zohydro, my first thought was fear and death. With there being so many addicts in the world today, and the numbers going up every day of the over doses, the thought of a drug having 10 times the amount of hydrocodone in it, such as Vicodin sent fear running threw my heart. I have suffered with my own “back problems” since I was only 17 yrs old. Since then I have been through everything from physical therapy to surgery. I have been on pain killers from tramadol to hydrocodone to morphine or oxycotine. I have numerous things that contribute to my pain that I suffer with every minute of every day. So I know what its like to finally have pain relief due to the drug I am taking. It all boils down to a money game. And if the big time business men and women think its going to take a dollar from their pocket, then they are going to do everything publicly they can to make us as consumers believe this drug is the worse thing mankind has ever developed. Reality is that if someones going to OD, then they are going to do it with whatever drug they can get ahold of at the time! What Im trying to say is if you could take a hydrocodone 10/650 and scrape the tylenol out of it and discard it because that alone is causeing your body more pain than it is good then thats what you would do. As long as the dose of 10 mg of hydro is left the same and not raised higher then we should’nt have any worries about it. For the people that are selling their prescriptions or buying pills on the street illegaley, their actions will probly not change from what it is now. Doctors should drug test every patient they have on narcotics monthly to make sure they are taking them. If a person is in so much pain that they need to be on strong pain meds, then they should have no problem in agreeing to a monthly drug screen test. It would benifit the patient as well as the Dr.

January 6, 2012 at 12:36 pm
(7) Leonard Wenston says:

My husband has suffered from chronic pain for 20+ years. The location is referred to as the lower right quadrant. The pain comes and goes about every 3 hours and the morning pain is the worst. There has been no actual diagnosis and he now takes 30 mg of morphine twice a day but still cannot function normally when the pain occurs. I feel that it is not helping and must be increased. He must be away from people, remove outer clothing as if it is restrictive and either lies on the carpet or sits on the couch, leaning away from his right side. He cannot have conversation at this time and tries to read magazines to control his thoughts. Only time changes this pain and when it is gone, he is back to normal. The only time the pain went away in 20 years was when he was hospitalized for histoplasmosis. We have list available of doctors and pain clinics he has been to, medications that have been tried and procedures that were tried. He did have some improvement when he was taking oxycontin and clonozopam, but the doctors didn’t want to continue with these drugs.
Leonard Wenston
Pharmaspider.com

January 6, 2012 at 12:52 pm
(8) AmiFK says:

Why doesn’t anyone ever suggest the fact that if all of the billions of dollars that go into developing all of these pain meds went into discovering permanent solutions for pain, including how to permanently destroy a nerve without it regenerating itself, these potent pain meds wouldn’t be a big problem? There would be no need for more than short term usage, and many people would not become addicted. Do any of you WANT to be popping pills for the rest of your life? Pills don’t cure anything, they only temporarily treat symptoms. The answer (except for the drug companies) aren’t to be on pills chronically for your entire life.

January 6, 2012 at 8:18 pm
(9) jonny says:

AmiaFK- that was an extremely foolish answer. There are profiteers in the medical field whether research is being conducted to manage illnesses surgically or medically. These is a company that specifically makes drugs that do help people. I commend these companies for designing new drug formulations in order to help chronic pain patients. As a sufferer myself of a horrible nervous system disorder Thoarasic Outlet Stndrome, my life has been saved by strong narcotics. I did have surgery and it is not a cure by any means. These drugs allow me to go on day to day. I give props to the drug makers, maybe zohydro will be the next big thing for me.

January 7, 2012 at 6:12 am
(10) Rob says:

Darvon/Darvocet (propoxyphene) was a drug that caused heart arrythmia in many of it’s users. Two of my family members developed heart problems because of the drug. There are several other medications that work just as well if not better than propoxyphene. For example Vicodin (hydrocodone) has roughly the same analgesic strength as propoxyphene and has not been found to cause any long term health problems. However if you’re on COAT (Chronic Opioid Analgesic Therapy) then there is always going to be that one long term health risk of becoming dependent. My point is that arthritis patients should not be complaining about their beloved “Darvon” being removed from the market. That’s just ignorance. Do I think that a time-released version of hydrocodone is going to be abused? Yes. Do I think they should add this to the prescription opioid market? Probably not. This is exactly what Purdue Pharma did with Oxycontin and look how that turned out. The fact of the matter is that there are already several medications out there that doctors can choose from for opioid therapy. Codeine, Hydrocodone, Oxycodone, Morphine, Oxymorphone, Fentanyl, Dilaudid. However, the acetaminophen that is in hydrocodone prescriptions now is not good for the livers of the users.

January 7, 2012 at 1:42 pm
(11) Katherine Wolfe says:

I think the big problem with time-release opiates is that they aren’t tamper-proof. If you really want to get all the dose all at once you can – unfortunately it doesn’t seem to get through to a lot of people that defeating the time-release will give you a lot more than the strength on the bottle indicates.

I think one thing that would help a lot with accidental overdoses is to clearly state how much opiate is in the pill. This way kids looking for a joy ride on Mom’s medication will know what they’re getting into.

January 7, 2012 at 5:44 pm
(12) keenspirit says:

@Johnny, I don’t think AmiFK’s comment is foolish at all. I think that is how things should be. Her point about finding ways to treat the ailment and not chase symptoms is spot on! We should be looking at cures, not just band-aids. Pharmaceutical companies shouldn’t be making drugs for the mere sake of making a profit! The problem is that the pharmaceutical industry is one of the top 5 most profitable businesses, and it is on the backs of people like us with chronic pain and chronic disease. The fact that our medical system is based primarily on profit does not negate AmiFK’s comment at all. I refuse to believe that just because things are the way they are now doesn’t mean we have to continue to accept it, nor allow it to continue.

In regards to the Zohydro, I believe it should be made available to people when the other medications do not work to begin with or over time are no longer effective. I agree that the system should not be changed because of the small percentage of people who are abusing the medications. I am certainly concerned for their well being, but we each have to take responsibility for our own lives. And the reality is if someone has a predisposition to addiction, then it really doesn’t matter if they are taking the lowest dosage of Vicodine. If they start taking too much of it, then there can be trouble…period. Ultimately it comes down to each of us managing our own health care, which means we should have access to any medication could assist with our medical condition(s) and level of pain.

Sadly we also have to worry about the risk of side effects from each of these pain medications, in addition to addiction concerns. The reality is that the FDA isn’t there to determine risks; they are there to determine the efficacy of the drugs, not if they are ‘safe’. I am more concerned about this than I am addiction because at least I get to make the choice about how much medication I take.

January 8, 2012 at 6:59 pm
(13) Michele says:

To AmiFK, I would guess that you don’t have a chronic, degenerative, disabling disease or you would understand the need for pain medication. I have observed that when someone is in “real” pain they seldom become addicted to their pain meds because the meds actually go to work on the pain and don’t make you feel all warm and fuzzy. I have been taking the same amount of Hydrocodone (two a day) for about 15 years obviously that’s not an addiction. However, I need those two pills a day or my body is unbearable. But I have also been having some liver problems lately and that’s scary.

January 8, 2012 at 7:13 pm
(14) Dr. Who says:

I think it is High Time to return to the days when it was totality discretionary within the medical profession.
to prescribe Opiate drugs to those who suffer Chronic Pain!
Every Person is entitled to assessment as an individual and to be offered the Best treatment in the light of their condition, situation & needs. NO Legislator, No Judge, No District Attorney, No Police Official & NO Narcotics Agent is qualified to make such an assessment! If as the result of such an assessment and continued experience in treating the individual suffering from a medical condition involving Chronic Pain, it should be decided that the best treatment is to prescribe for them a Narcotic pain medication… then they are entitled to this treatment! This “Zohydro” seems like a Winner to me! PEACE!

January 10, 2012 at 7:10 am
(15) Ben says:

As a recovering addict, I can say that tamper proofing oxy didn’t work; it got you just as high, not as quick. I question the need for a painkiller that could kill you with one dose (unless you’re hardcore, like I was). Not to mention the fact that you already have product like fentanyl, which is supposed to do the same thing as Zohydro. If the FDA approves this crap, it’s further proof that Big Pharma has the federal government in it’s pocket. As or fedral agencies, this will overwhelm the DEA, the FBI, and the ATF.

January 20, 2012 at 5:56 am
(16) RAFA says:

WELCOME ZOHIDRO NOW I’M TAKING HYDROCODONE 7.5MG/500MG TABS PLUS I TAKE AN ETODOLAC 600 ERIN THE NIGHTS I FEEL SOME COMFORT BUT IN THE MORNING MI STOMACH SWELLING, I HAVE PINCHED NERVES I DONT FIND WHAT TO TAKE BECAUSE ALL OF THESE HAVE ACETAMINOPHEN AND I’M NOT SUPOSED DUE TO MY HEART CONDITION THAT I TAKE PLAVIX TOO. IF SOMEBODY ELSE HAVE A GOOD IDEA PLEASE POST.MY MAIL IS rafa_cadillac@yahoo.com GOD BLESS ALL OF YOU THANKS

January 30, 2012 at 3:50 pm
(17) Street Wise says:

I can’t wait. I’ll get a script for these and probably get $35-50 bucks a pill on the street. I have faked out a dozen docs for my “chronic back pain” already get a steady stream of Oxycodone every month that I turn into instant cash. I have never had one doc ever look me up in the drug registry and I doubt they will start doing it now.

March 7, 2012 at 3:13 pm
(18) laurel fen says:

And from street-wise— there is your answer-More compliance with the drug registry, and instant jail time for the sellers/abusers-and if it means an immediate withdrawal while locked up, so be it! I have had “tylenol free” hydrocodone, from a compounding pharmacy combined with dextromethorphan, and for my fibromyalgia, it worked far better than any of the other more powerful opiates. I have tried morphine, dilaudid, fentanyl-but none work as well as hydrocodone, and if the law would stop focusing on the honest chronic pain patient and work on putting away the abusers, the nation’s epidemic would start to come under control.

April 6, 2012 at 5:53 am
(19) Rhonda Holt says:

I have been on many time release meds for my bladder cancer, and the ones that have worked well have been taken and reformulated to the point that they make you sick and they are intolerable to the digestive tract..I find this unfair to change these medications that work for chronic pain life sufferers and do not think they should change our medication because of the abusers and addicts who do terrible things to this medication to cause it to be changed so they no longer can abuse it, well it affects those of us who need it and it has worked well for and now that they change it for the abusers it also changes it for the pain suffer patients who no longer can tolerate it…This makes no sense at all and the abusers are going to find away weather it is changed or not, but the true chronic pain suffers are going to suffer and not be able to tolerate nor no longer take the medication at all.. I truly wish the FDA and pharmaceutical companies would look at what they are doing and see how many more people have to suffer because they need to reformulate it for tamper proof for the abusers when they still will find a way.. And all of us chronic pain life suffer patients will have to suffer and I do hope something can be done for those who truly need it and do not abuse it and it works so well for them and they find they no longer can take it so they have to keep finding another medication only for it too to be reformulated because of the abusers…In the end its us and the true life time pain suffers who really do end up suffering while the abusers still find a way to abuse the reformulated medications.. I do wish someone would look into this and see what is truly important here and what is needed and that is to help the honest true chronic pain patients who truly need it.

April 7, 2012 at 12:51 am
(20) Lamava says:

I wonder if the FDA would be smart enough to put guide lines on Zohydro so that only those with Chronic Pain would have access? Such as only available to patients who have been on other pain med’s for 2 years or longer etc… I have been on Hydrocodone for almost 4 years now and worried about my liver. Hope they find a way to get better meds to the people who need them.

April 7, 2012 at 3:03 pm
(21) Roger says:

Yes it is nice to hear about this new time released drug but like many here have said , what docor will prescribed this to me. I have a pain management docor that just told me that he could put me on a time release med along with what I am taking now but i would be also put on an abuser list. He said that even though I am not an abuser , by me being prescribed that type of medicine I would still be on the list. Then if I ever changed doctors or he decided to move, getting another doctor to give me the same thing would be very hard. He also said if O bomb a ‘s helth plan goes through the supreme court then it’s going to be even harder to get these type of drugs. He told me as a doctor he does practice medice anymore. He only can do as the DEA and the ATF guides him to do or risk putting his license in jeopardy. I told him that sounded like socialism and he agreed but who do you fight. Power of the people where are you at, help is needed before it’s too late..

April 7, 2012 at 3:18 pm
(22) Roger says:

I forgot to mention that the comment Dr. Who made was right on..Way to go. Our freedom is at stake. Doctors, if you have money then fight to keep your freedom to practice and not just sit back and take orders from non-doctors. You have worked hard to earn that degree. Make it mean something. I suffer from pain and I go to the doctor so let him and I decide what is right for me. Thats freedom.

July 4, 2012 at 8:47 pm
(23) Timberghost says:

I’m a Chronic pain IP patient. IP stands for intractable pain. While my pain is severe. Sometimes us people with pain that is chronic in nature need new medications to keep up with the ever changing world of pain. Yes, there are people that ruin it for people like myself. But on the other hand if your not just going to a “pill mill” to get your medications for pain. Then you the patient are protected more an more from yourself or people that can’t control there meds; the addicts. The new REMS system to prevent abuse andto help the provider with helping to do the right thing rather than handing over a precription for a bottle of pills. Also if your doctor is following protocal. By giving pop urinalsis, counting pills every visit. Making you sign a contract, using one pharmacy, and making sure that your using one doctor. Then it is making it more difficult for abusers to abuse the medication that helps the people like myself that have been in severe pain for 24 1/2 yrs. Plus you people that take pain meds do not brag or tell anyone about it. And keep you medication LOCKED at all times. Then there will be less problems.

August 5, 2012 at 3:31 pm
(24) kyle says:

It’s ridiculous that my pain relief depends on the safety of dope heads. Hydro is the only thing that works for me, nothing else. It’s the only drug that takes the edge off while allowing me to think straight. It’s sucks that my liver needs to suffer bc of this, with all of the tylenol I have to take right now. This drug would be awesome for me. The old oxy worked but it made me stupid, couldn’t get my work done. Op’s suck, higher dose is needed and I bet this new one will have the same crappy mechanism. I wish they would just legalize street drugs already so my pain management wouldn’t be affected by the druggies

December 5, 2012 at 3:05 pm
(25) BarbL says:

I’ve had chronic pain from osteoarthritis for about 6 years. It had been well-managed by taking Vicodin as directed. Then, due to the fear generated by some tabloid news reporting, the FDA broke..uh, reformulated Vicodin. It now doesn’t work nearly as well, manages pain less.
Now, Zohydro is up for review in a climate of fear, sensational news reporting, and concern for the junkies who take it to get high. I haven’t heard anyone stating that, just maybe, pain patients should be considered first. After all, Zohydro was made for them, not the addicts.
I hardly dare hope that the FDA will do the right thing, that is, make Zohydro a Schedule 2 drug and monitor its use. It should be available to pain patients, should be approved and used cautiously.
In these comments there are some references to getting high on the drug and/or selling it. I truly hate these people at this point. The quality of my life depends on pain management, and these selfish pigs endanger that.
Let’s stop catering to their sick, selfish needs. Seriously, cull the herd. No one forces them to get high.
Pain patients first, last, always!! Let us have the medication which was made for us. If you have never experienced chronic pain, please keep your comments to yourself because you know nothing about its effects, day after day.

January 8, 2013 at 5:49 pm
(26) atg says:

TheFDA and others are not concerned with patients. Just abusers. At 51 yrs of age, they are intent on killing my liver. Zohydro in different strength is easily. Monitoring. Already done by responsible m.DS. street use is always going to occur as it has for decades. Hasn’t been stopped yet. So a beneficial drug is stopped and we true patients suffer tylenol poisening and doses that have to be kept low and may not work. Concentration on EXISTING PAIN SUFFERERS FIRST. There will always be street hustlers.

January 17, 2013 at 9:01 pm
(27) Barbara says:

What about the real chronic pain patients who do not have a quality of life without pain medication? I am a nurse and know a lot about addiction. I am not an addict. But now I have to go sit with all the addicts at the cash pain clinic because my doctor can no longer prescribe meds for pain. I can only hope I don’t live too long.

August 2, 2013 at 11:44 pm
(28) atg says:

Barbara. I have felt.that way. Please! Live! Help is on the way. Alot of brave Drs are fighting back. To do no harm. Patients must fight back. Zohydro or competition will happen. If they even took APAP out of Vicodin, Norco, just tabs of 5mg or 10mg Hydrocodone, what would it change? No liver damage. And better absorption plus Tylenol would have to settle.for over counter sales. Pure regular fast acting would work well. Be.scheduled same as strength is same as APAP added. And no fear of large time release doses tampered with. Ready to manufacture.

August 12, 2013 at 1:26 am
(29) Joseph Rosado says:

When I first read about Zohydro I felt a sense of relief and hope. I contacted Zogenix to ask if I may participate in their testing. They were courteous in response that the double blinds had been completed and things were rapping up. Next was waiting for the FDA(or feet dragging asses) as my buddy would call them. As for me, my life is reduced to a prison within my home,not being able to travel. Currently my wife and family are in North Carolina while I sit home lonely in despair in NJ. I long for the days of walking in the park,riding my bike, going to my kids tennis matches, a full nights sleep,sex without pain, not being jeered at by fat slobs because my balance is off. I have Adhesive Arachnoiditis caused by surgery and those GD Epidurals.
I’d like to try Zohydro. I believe it would help me tremendously. Besides I’m a grown man. I don’t need a bunch of Bureacrats trying to PROTECT me when they can’t even stop illegals from overrunning the country.

October 25, 2013 at 10:47 pm
(30) Mindy says:

I have been a chronic pain sufferer since December 1986, following a jaw reconstruction surgery. Here I am nearly 27 years later and it is literally a living hell.
I struggle daily and view getting a bath, getting dressed, and MAYBE getting my dishes done or some light dusting as an accomplishment…a far cry from who I used to be. I suffer from bilateral Atypical Trigeminal Neuralgia (ATN), bilateral Trigeminal Neuralgia (TN) aka the “Suicide Disease”, Occpipital Neuralgia (ON), & Glossopharyngeal Neuralgia (GPN)…among other things. My neuralgias have made my quality of life take a major nose dive. The longer they go on, the more frequent and more severe they become. No cure means no life. I am only days shy of becoming 44 years old. I forget what it is like to feel good or to truly be happy..

October 25, 2013 at 10:48 pm
(31) Mindy says:

It makes me extremely angry that while I am made to feel like a “drug seeker”, “addict”, “scum”, “criminals”, etc. by the very health care professionals that should know the difference, our so called “War on Drugs” is more worried about the lives of those who typically CHOSE their own hell rather than the lives of those who, if given the chance, would GLADLY pick being pain free over these stupid drugs. Why is it, as society, we are hell bent to save the lives of people who typically don’t give a damn about their own while making it harder and harder for those truly in need to get that help they deserve. It should be a basic human right to NOT be in constant pain.

October 25, 2013 at 10:49 pm
(32) Mindy says:

It seems we treat mangy mutts in second rate shelters more humanely than we do most terminally ill or chronic pain sufferers. For those of you like “Street Wise”…shame on you. There are many people like me who are at home laying in bed either sleeping their life away to avoid pain or laying there begging a loved one to kill them and put them out of their misery simply because people like YOU are to damn lazy to go out and find honest work and feel your easy quick cash is more important than the lives of people who did not create their own hell. I pray to God you are never in my shoes. On second thought, maybe I do. I wish you could walk in my shoes for only one short week. I guarantee you would never choose to be a selfish POS while others are forced to go without just because you refuse to be an honest (wo)man.

October 25, 2013 at 10:50 pm
(33) Mindy says:

You probably don’t give a damn…as long as you can turn a quick buck.
The “War on Drugs” is a major flop. While the shady doctors and people faking health issues are still getting their drugs and/or money…it’s those who truly need the help that are being increasingly turned away. It’s time for “Plan B”. Why it is not handled as such is beyond me: You want to chance killing yourself or your friends/customers…knock yourself out. Go kill yourself. It should be ruled a suicide and not a single penny in life insurance should be able to be collected. I will GLADLY submit to a monthly drug test AT MY OWN EXPENSE if that is what it means to prove that I am not screwing others over. Shame on you. Judgement day will come. You better pray to God hell comes complete with a script of opioids and an endless supply of ice cubes or else you are screwed without a kiss. Hope you sleep good tonight knowing someones life is ending because you’er a selfish rat bastard!

January 19, 2014 at 7:56 am
(34) Meggan says:

Not smart idea and disappointed to hear product 10 times per potent than vicodin and not abuse proof. Possibly why more than 25 Attorney Generals trying to remove Zohydro ER off shelves for public.

February 28, 2014 at 1:11 am
(35) Brittany says:

Im young but have really bad norapathey lupus fybermialgia diabetes MRSA an my bladder no longer works an go threw major spasms im in so much pain I cant stand it an its said I should be enjoying life im young its so bad I cant walk threw Wal-Mart anymore..an im getting married in may an just dress shopping was so hard I hurt so bad an im on meds but i am on hydrocodone that has so much Tylenol in it im afrade my liver an kidneys already going threw alot with my nurves damage an diabetes dont need that but I need something to help the pain..an it makes me so mad that people out there abuse meds when there is people like I in so much need for it an because im so young doctors are afrade that im gonna abuse or get addicted even tho I fallow what they say…so im hopeing this new drug will help us ones that need it the most..an hope an pray that some how people will see it not haveing Tylenol in it is sum what better…but ever medications have a list full of bad things…but what can we do us very sick people have to take them

February 28, 2014 at 2:50 am
(36) brenda says:

I have major pain due to scoliosious, arthritis, ostioporosis, and degenerative bone disease. Iam currently on #10 loracet, all it does is take the edge off! Due to people abusing opoids, we that have real chronic pain are being punished because of addicts! This new drug may finally bring me to where I no longer feel like I just rather die then live in this pain!

March 7, 2014 at 6:58 am
(37) Buck says:

I have been using Hydrocodone (from a compounding pharmacy) for 3+ years now. I get 120 per month at a cost of $90. This new drug (Zohydro) sounds about the same as what I have been taking successfully. I have NO insurance though and currently have to go to the doctor every month (and take a pee test) at a cost of $110 a month. So it’s $200 a month JUST to alleviate the pain and every month cutting it close to running out. Any idea what the Zohydro cost will be for similar dosages? Also, I used to have to go to the doctor every two months and take a pee test every 3rd visit (twice a year). Other than the expense I don’t mind; I have nothing to hide. Did the laws change (in Georgia) to require monthly visits or is this just a way for the prescribing physician (I had to change because my regular doc retired) to make more money? My old doc did not require monthly visits. Thanks for any input.

March 9, 2014 at 12:04 am
(38) chris says:

liberal democrats know whats best for everyone and they never ever take responsibility for anything, its always the pills fault or the guns fault, its never ever about personal responsibility so the deny everyone else who live in pain a chance to be pain free, they just know whats best for everyone, what you should drink what you should drive what you should wear, nauseating

April 3, 2014 at 5:08 pm
(39) Deb says:

Has anyone tried the new drug Zohydro ER yet? If so, what dose are you on and how is it working for you. Are you having any problems getting your scripts filled? How about cost? I’ve read so much about this and all of your comments looking forward to it. I was just wondering if any of the posters on here actually went out and got it.

April 8, 2014 at 2:16 pm
(40) Bill says:

I live w/ chronic pain. For 25 yrs. When a person finds a treatment that works and we can live a so called “normal life ” it makes me angry when FDA stick their big noses in and screw it up. When a medication has a potential to make a lot of money, they turn a blind eye and at times fast track the drug because greed makes people do bad things. Then after people die or get a disability due to a problem w/ the drug they then remove it. After the damage is done. However when I find a drug I research it and discuss it w/ my Dr. Now I start to get the speach that I am on a high dose and his list of whys and why nots. What Dr.s don’t understand is quality of life is not limited to length but also how well your time is. If I take a drug that might be hazardous to me, I believe I should be the one to make the choice about the dose that works for me. No Dr. can walk in a patients shoes. I was a functional worker using my drug until the Dr. felt the dose was too high and long term use might give me a stroke or heart attack. I took and take EKG”s. I have and always did have perfect results.Well after he lowered my dose, added ANOTHER narcotic I had to take disability. Screwed me out of over $75.000.00 a year in income and has made my quality of life below what I call a life. No matter how bad I ever felt, I never thought about ending my life. But since disability I have had that thought more than a few times. I never could do it because I love my wife and kids and I could never do that to them. But if a person like me can have those thoughts I know someone w/ pain like mine or worse will end their life. Because a Dr made the decision to lower or change a drug that works for that patient. Walk a mile in my shoes has never had a better situation where that line really fits. Thank you for taking your time to read this. Writing it is another way to help chronic pain sufferers deal Thank you again. And take care of your self, no one else will.

April 16, 2014 at 11:59 am
(41) sunshine says:

I know this is an old thread but felt I should post. I just started Zohydro. The first 3 days were rough but I am sensitive to every single ER Med out there. On the third evening I felt better but still had nausea. I don’t do nausea well at all! My pain is not completely gone as I have full body pain. I still need break through meds as it does not seem to last seem to last 12 hours like many ER meds. I was terrified by all of the hype but besides initially feeling sleepy and finally taking Zofran for the nausea. I don’t like taking a lot of meds at once. It has been less. Then one week and I feel fine. I seem to tolerate hydrocodone for some reason. My neck pain is so much better and full body pain is still there but I was in a bad flare with Fibro and Epstein Barr. All of the others made me feel depressed or like a vegetable! So I give it a good review.

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