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Carol Eustice

Savella - What Fibromyalgia Patients Need to Know

By January 27, 2009

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Savella was approved by the FDA for the management of fibromyalgia on January 14, 2009. While it was in clinical trials, Savella (a selective serotonin and norepinephrine dual reuptake inhibitor) was known by its generic name, milnacipran HCl.

Fibromyalgia can occur as a primary syndrome characterized by muscular pain or as a secondary syndrome to other rheumatic diseases. It is possible to have fibromyalgia syndrome as well as another rheumatic disease. Patients with rheumatoid arthritis, lupus, or ankylosing spondylitis are at increased risk of also developing fibromyalgia syndrome.

How does Savella improve fibromyalgia symptoms? What side effects, warnings, and precautions are associated with the drug? Savella is the third drug to be approved for fibromyaglia -- Cymbalta and Lyrica are the other two. Savella is expected to be available in pharmacies by March 2009. You can learn more in Savella - What You Need to Know.

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Photo by Frances Twitty (iStockphoto)

Comments
March 23, 2009 at 1:31 pm
(1) Larry Payton says:

I understand that the release date of Savella has been pushed back to this summer. Has anyone seen an exact date?

March 24, 2009 at 7:40 pm
(2) T.Sampson says:

Can someone tell me exactly when Savella will be available? Thanks

March 24, 2009 at 9:40 pm
(3) Carol says:

The company is saying mid-2009 and has not been more specific than that so far. Here’s their press release: http://www.cypressbio.com/news/20090306.pdf

May 14, 2009 at 1:31 pm
(4) Larry Abplanalp says:

Guess it’s available. My wife came home yesterday with samples from her physician.
I’m wondering if it has any advantage over Cymbalta since both act by Norepinephrine and Serotonin Uptake…. Guess we’ll see…

May 14, 2009 at 4:22 pm
(5) Glenda says:

I just received the 14 day sample pack today from the doctor. I’ve got high hopes!

May 18, 2009 at 11:18 am
(6) Lisa says:

If anyone has started these meds could you let me know if its helping? I tried Cymbalta and I am getting ready to try Savella.

May 20, 2009 at 10:31 pm
(7) katrinka says:

My doctor just put me on it about a week ago and so far I have noticed a difference. I was taken off Cymbalta because it was not doing anything and this seems to be making a difference in a short time. I am finally able to say I have a hope.

May 22, 2009 at 11:56 am
(8) vjenkins says:

I just started a few days ago and I truly believe that I feel better with more strength noted. There is a 2 week tapering to starting the drug and right now I am taking the minimal dose so I can’t wait to see how much better I am going to feel when I reach the actual daily dose regime.

May 24, 2009 at 10:17 am
(9) KD says:

I am on day 11 of the introductory packet of Savella–finally it seems there is something that seems to be helping..I only say seems because I do feel better-but big question will be for how long will this work..I hope it will be afor a long time..I seem to have more energy and though I still hurt it’s not as bad..I have actually felt like mowing the lawn and working in the garden..YEAH!

May 24, 2009 at 10:44 am
(10) Debbie says:

I have been on Savella now for 5 days. I still have soreness and stiff in the morning but I have noticed I am not having much of the muscle spasms. I went out with friends last night and my girlfriend said you seem like your feeling better. Its still early yet, so I am hoping !! You are not going to get better overnight, it takes time.

May 27, 2009 at 7:24 pm
(11) Leona Bourque says:

I have been on cymbalta for nearly 4 years. It made major difference in my life until this past winter. Perhaps it may be time to change the Cymbalta.
Sincerely,
LB

June 10, 2009 at 11:16 pm
(12) jane says:

I have been on cymbalta for 2 yrs and it worked some what. but, recently it has started making me vomit and sick in the bathroom. I am on day 6 of the savella and I can really tell a great improvement. I am on medicare now so I don’t know how long it will take to get it preauthorized. I am feeling better and better everyday. I still have to take my pain meds and muscle spasm meds, but I am feeling better. I am hoping that after 3 yrs of dealing with ankylosing spondilitis, osteoarthritis and fibromyalgia that I may have hopes of finally getting part of my life back. good luck to everyone.

June 11, 2009 at 7:00 pm
(13) SUE says:

ANOTHER NEW MED…I AM REALLY PRAYING THIS ONES WORKS FOR ME. I’VE HAD ALL THE MEDS, THERAPY’S AND PAIN CLINICS, ACUPUNTURES AND POOL THERAPIES OUT THERE. SO FAR NOTHING HAS WORKED. I’M TRYING TO STAY POSITIVE AND HAVE HEARD SOME GOOD THINGS ABOUT THIS NEW DRUG. MAYBE THIS IS THE ONE FOR ME.GOOD LUCK YOU ALL…..I PRAY YOU GET SOME RELIEF.I START TOMORROW.

June 12, 2009 at 2:55 pm
(14) Reiser says:

This drug will make millions, because people who are in pain will pay anything to feel free again.

Here’s an alternative for people with fibromyalgia, myofascial pain syndrome, and other related disorders: research the ways that magnesium, B12, and vitamin D deficiencies are directly implicated in depression, anxiety, and musculoskeletal pain.

This drug is just an antidepressant in disguise. It’s an SSRI that calms you down by increasing the uptake of norepinephrine, the anti-adrenaline. It will treat your symptoms but not the disease. Go to your doctor, but instead of asking for this drug, ask for blood tests that show serum levels of vitamind B12 and 25-hydroxyvitamin D. You might be surprised at what you find.

June 17, 2009 at 12:35 pm
(15) Aida says:

I was on Cymbolta for a year. Felt GREAT, but put on 25 pounds. I hate the weight gain, so my doctor agreed to let me try Savalle. I’m on my third day of my 14 day pack. I’m feeling light headed and a little sad. I think the sadness is because I stopped taking Cymbolta and my body misses it. My doctor tapered me off Cymbolta before starting me on Savalle. Hopefully the light headiness will go away within the next few days.

June 18, 2009 at 12:59 am
(16) Tammy says:

I started Savella three wks ago. I told my rheumatologist that if I went off Cymbalta I would cry all the time. It was rough for the first two weeks but I am starting to level out. What I love about it is how I feel in the morning. I feel more alive and the pain is better. It made me pretty nauseous and dizzy for the first week. I have been having some trouble with depression and irritability which I plan to discuss with my doctor. I do enjoy not being completely exhausted all the time I just wish it wasn’t so expensive. I didn’t have any trouble getting it pre authorized but it is third tier and my insurance isn’t going to pay much.

June 19, 2009 at 5:01 pm
(17) Charles Riddle says:

Good News! It’s here SAVELLA my wife just got her Savella prescription and we are praying that it will help her.

GOOD LUCK TO ALL.

June 22, 2009 at 12:16 pm
(18) Joe G says:

I just started Savella about three days ago. Praying that it works!!! (have already seen slight difference in my fingers and mood) =)

June 26, 2009 at 10:33 pm
(19) allie says:

its available now..my mom just started taking it

June 28, 2009 at 7:54 pm
(20) Donna says:

I just started taking the savella hope it works. For all of you poeple with out insurance or little coverage ask your doctor for a coupon from savella that gives 6 weeks free with a written script my doctor gave it to me. Also has anyone taken Lyrcia and Savella together and if so how are they working for you ? my doctoe just put me on both.

June 29, 2009 at 10:12 am
(21) Joe says:

Now on day 7 (full dose) and not feeling so well. Dizzy, nauseous, super tired, and kinda pissy…

Not sure if this will eventually go away once my body gets used to the dosage… How are the rest of you guys doing?

July 3, 2009 at 11:20 am
(22) Deb says:

Just got a sample pack, building up on the dosage slowly and my doctor recommended taking it even slower they its say on the packet make it stretch to 21 day so the side effect are easier to adjust too. After that you will be on a 100 mgs daily.

July 3, 2009 at 9:43 pm
(23) bunny says:

My vision has decreased greatly since taking Savella.Has this happened to anyone else?

July 4, 2009 at 6:00 pm
(24) Helen says:

I am on my 4th day with Savella – beginning 25 mg.x 2 daily. Very light-headed and very emotional. Was on 150mg. of Effexor & the dr. just did a switch from that med to the Savella. Feel sensation of air thru my ears @ times. Haven’t noticed any change in pain level. Really worried about the emotional side affect.

July 6, 2009 at 2:12 pm
(25) kimberc says:

I am glad to hear the this med has helped some of you. My Dr. gave me a 30day trial pack and I am kind of afraid of taking it. I am on Lyrica and Effexor and feel good for the first time in years. Still trying to make up my mind if I want to take the chance on something else.

July 8, 2009 at 8:51 am
(26) Mary says:

I have been on zoloft for 25 years up to 300-400 at times. Darvocet 3 X day and ER visits monthly. I tried Lyica and the first day my husband had to physically hold me since I was feeling disconnected from body and life.I had nausea, headache and pain increased in just one dose.Had to stop that! Then I tried Savella. I have been taking it for two weeks at the 50mg twice a day. It is working so well that I am able to be on a treadmill for 5 mins in am and have lost 19lbs. NO pain and no additioanl drugs such as Darvocet m tizandine and the Zoloft was reduced to 50mg..A first. Thank you SAVELLA

July 8, 2009 at 3:18 pm
(27) Kelly says:

I started Savella 8 days ago…I can’t honestly say that I have had any relief w/the pain yet…I am extremely emotional though, sweat as much as I did with Cymbalta, still a little light headed, BUT…my eyesight has decreased also!!!!???? This is very scary to me…I am hoping that once I am completely used to the drug it will work, because the Cymbalta only worked about 4 months and then nothing… Good luck to all!

July 9, 2009 at 12:51 am
(28) Kirsten says:

I am on 300 mg. of Gabapentin and 25 mg. of Savella (split into 2 doses), and am pain-free most days. My doctor started me on the titation pack only to find out once I was feeling much improved, my insurance will not cover Savella until 2021, so I am considering paying for it myself. I tried Lyrica but there were too many side effects for me. Cymbalta is my only other option that insurance will cover, and I’ve seen the list of side effects, and they are too close to Effexor for me.

July 11, 2009 at 10:08 am
(29) kim says:

I have been on Lyrica for over a year. The weight gain and the blurry vision and not being able to get my eyes to focus became worse as time when on. Except for those side effects it worked well for me. My Dr. switched me straight from Lyrica to the Cymbalta I have never been so sick in all my life. I couldn’t get out of bed for 4 days. So now I am trying the Savella 14 day trial pack. I am after 2 days already starting to feel nauseated and feel like I am going to vomit. Anyone else having a adverse reaction to the cymbalta or the savella. Very strange because I had none of this when I first started the lyrica. Tks. and I hope everyone in pain finds some release from it.

July 13, 2009 at 5:50 pm
(30) Neil says:

Reading all your comments makes me scared, Im going to be sick forever arent I? Im 20 years old, I don’t know why this is happening

July 14, 2009 at 12:01 am
(31) Kate says:

Day 7 for me – initial side effects included headache and nausea — both were uncomfortable but manageable and pretty much left after 2-3 day. In seven days, have not felt the fibro pain! ~ except: the day after I overdid pretty majorly. So…we still pace ourselves. The release from nerve pain is incredible. The energy to move again is so renewing. And I just read that Fibro doesn’t always last forever….so that is my hope and prayer for the young who are encountering this terrible pain so early in life.

July 14, 2009 at 11:39 am
(32) donna says:

well i also started with the 2 week titration pack, slowly creeping up tp 100 mg a day. the drug manufacturers are having a field day with us, aint they? pushing the blister packs to get more people dependant on them. some med’s do help us but there is a pill for everything. i visit my dr. monthly for my med.’s and while waiting the suited reps flys in and out. that bothers me. i hope this medicine works for me. i was diagnosed 3 years ago w fibro and have arthritis real bad and alot of depression and sadness. but i think cymbalta is a horrible drug. i was getting worse and the dr. would increase it, and continued to increase it til i said stop , and weened myself off of it. and lyrica worked for my pain, but the extra pounds were too much for me also effexor is a weight gaining drug if ever i seen. good luck to all of you out there but i think it is in the air, and what we eat that keeps us sick, and this crazy world.

July 15, 2009 at 12:58 pm
(33) Linda says:

I havent tried savella yet and dont know if i even want to. Im been on cymbalta for a few years now. Im alos on oxycontin, fentanyl patch, lorazapam for anxiety ( which sometimes runs high when youre in day 5 of flareup and nothing is helping), ambien and amytriptyling for sleep. im on a few others like for kidney problems and ibs , and also on soma for muscle relaxer. I wish they could just mix it all up, make a cocktail, take it one time, even twice a day and youre done. i am so tired of medication, and all its side effects, that im afraid to wean off one just to get on another one with different side effects. Ive asked my pain management doc about savella, he says its almost like cymbalta. I dont know about that since he’s not taking it. so im still waiting till i find people who have tried it, for a while and say its working better than cymbalta.tried lyrica for about a month or month and a half, was swollen all over,feet,face, hands,eyes, i stopped it. I think all the docs are doing are simply treating each symptom of fibro with a pill that takes care of THAT symptom. i dont know where it will end.

July 15, 2009 at 2:58 pm
(34) VickiLynn says:

Well I have been batteling this back problem for 9 years three disc fushions and I tell you what I started the Savella and all is good, yes I am very sad but at the same time have lost two very important people in my life (so who knows). I would rather try taking this 1 pill twice daily at any cost rather than any of those stupid pain meds that do not give you a clear head. I also have an implanted stim for permament nerve damage to the L5-S1. Which also keeps me off pain meds, a clear head is better than anything else.

July 19, 2009 at 2:13 pm
(35) Paul says:

I started the drug a few days ago. My symptoms are weird nightmares that frequent, and a high fever. No nausea yet with it. So far it isn’t doing anything but I’m going to stick with it.

July 19, 2009 at 8:16 pm
(36) Lyn says:

I was on Savella for three weeks. I had been on other anti-depressans over the years but they made to very tired. Savella was to help with that. I started feeling very sad and angry, hit myself and tried to put a belt around my neck but my husband stopped me. I will 50 in a few months and have not have outbursts like this since I was a teenager. I stopped it and my doctor put be back on prozac. Just be careful, it will prorbably help a lot of people my it made me a million times worse.

July 22, 2009 at 2:17 am
(37) Irene says:

Does anyone know what a month’s supply of 100 mg daily will cost without insurance? I haven’t started my 28-day sample pack for that reason. My former company (I’m on COBRA at present and have applied for Social Security disability) switched to United Health last January and they would not cover my Nexium and now they are not covering my Celebrex, which I am taking one a day of, and my last renewal the pharmacy wanted $116.89 for 30 pills, so didn’t get it and have about 15 left. Any information will be greatly appreciated. Good luck to all and thank you for taking the time to post your much-appreciated comments. God Bless.

July 30, 2009 at 4:28 pm
(38) Denise Preston says:

This is for 20 year old Neil. No you won’t be in pain your whole life. Mine started in my 20′s. I have had many remissions. There are doctors that are really starting to understand that it’s a multi layered illness. I know 1 person on Savella. She said it is helping. The vision thing has come up-people should pay attention to that.

August 5, 2009 at 2:21 pm
(39) melanie says:

I do agree with 14) Reiser about getting your levels of V-D and B-12 tested and the specialized tests done. Also, I was iron deficient and did not know it. So many doctors do not look throughly into your complete blood profile which holds many clues, after all it is ‘your lifeline’…no pun intended. I improved so much after being on V-D and some B’s–BUT DO NOT just go out and start taking them without knowing what your levels are because you could not be doing your body any big favors! I have been on Cympalta for several years, and yes it was a huge life savor for my FMS. Guess we will have to see about this new drug. I always like to wait and see about new drugs, often they end up yanking them off the market it seems lately…hate to say it but it is true. Also, from someone who has FMS for so many years, I am just so tire of NEW things that promise results for something that is so unknown and misunderstood. hugs to all of you with FMS

August 6, 2009 at 10:56 pm
(40) DD says:

Hello. I’ve had severe weight gain with Lyrica, Effexor, Remeron… and a few others. Only Cymbalta seems to have helped a bit. But I have the following questions for those who have taken Sevella for atleast two plus months… if you’d be so kind as to answer:
1. have you noticed any significant weight gain?
2. any vision problems? have they improved or worsened?
3. nausea etc – has it stabilized or decreased after the initial few weeks of getting used to this med?
4. severe depression, suicidal thoughts for those who have never had them before?
5. anyone in Michigan whose doctor has prescribed Sevella for fibromyalgia?
6. Can you recommend any good physician who have helped with your fibromyalgia in Michigan please?

Please reply online or offline. Thank you so much and hope to hear from someone so that I can have some relief, however small!! Thank you and God bless!

August 11, 2009 at 6:02 pm
(41) Wanda says:

I have been taking Savella for one week just started 50 mg in am and 50 in pm…I can tell a small amount of difference in pain…although the one thing I have noticed is I am VERY emotional!!! I have cried for no reason over the past week, scary but very Hopeful that this works for my Fibro and Depression. Good Luck to all who are trying it, maybe after the adjustment we will be blessed! I PRAY so. Wanda

August 14, 2009 at 11:05 am
(42) Joe says:

Took myself off the drug… Was not doing a thing for me accept make miserable… Good luck to the rest of you!

August 14, 2009 at 10:42 pm
(43) Sherry says:

For those of you that are asking about the price of medications, I would like to suggest for you to go the manufacturer/pharmaceutical company of your medications to see if you might qualify for their patient assistant programs. Allot of the pharmaceutical companies offer patient assistance programs based on your income/tax returns. For the younger people with fms, I’ve had it since 1994 and have had flare ups about every 5 years, but the medication options are allot better now, & there are more options. Keep trying, find something that works for you, and please don’t ever give up. At least now most doctors are actually believing that fibro is not a fiber of our imagination and it is a disease. Here’s a hug to everyone that doesn’t hurt. ( )

I’ve been on Cymbalta for 3 yrs which was awesome for my depression, but no help for my pain. Tried Lyrica, no help for my pain, & gained 40 lbs. Ibuprofin has taken it’s toll on my stomache & is no longer an option, but never really worked. This last flare up has been active now for 18 mths & have been taking Vicodin, a controlled substance, for 12 mths. It never did really work, but did alleviate some of the pain and I don’t want to take a medication that would lead to a lifelong addiction. I am down to 1 in early am & 1 in the early afternoon.

I saw a pain specialist today & he said the Savella works differently than Cymbalta. He said, Savella works better on the nuerotransmitters in the brain & Savella is not used to treat depression. A chemical imbalance in the nerotransmitters has been linked to fms. For those of you taking Savella & are still suffering from depression, please talk to your doctor to get something to treat the depression. My doctor recommended for me to wean off of my Cymbalta at the same time as weaning on to Savella. Today is my first night time dose of Savella & I didn’t take my night Cymbalta. I still get to take my Amitripyline at night to help me sleep & is also an antidepressant. In 3 weeks I wull be completely done taking my Cymbalta & will be on Savella in it’s place. To all a good-night & hoping for a brighter less painful future for everyone.

August 15, 2009 at 2:12 am
(44) Carol says:

Savella for 1 week and I am starting to feel and little more control over my thoughts and the pain is trying to diminish. I also wear 100mcg Duragesic, Norco 10/325, Soma, Clonazepam, Xanax. The cocktail helps mine to some extent. I just received Social Security after 2 years trying with a lawyer. I think that is great!!!!!!! Good luck to all of you with Fibromyalgia/CFS God Bless You

August 18, 2009 at 9:39 am
(45) BRENDA says:

I WAS STARTED ON SAVELLA YESTERDAY,TOOK MY FIRST DOSE LAST NIGHT, AND THIS IS AUG.18TH 2009

August 18, 2009 at 4:17 pm
(46) Karen says:

I also just started the 4 week titration pack of Savella. Only on my second day. As stated by Sherry (post 43), my doctor also is having me wean off of Cymbalta while increasing the mg of Savella. I have fibro, and experience depression. My Goal is to eliminate Cymbalta since It wasn’t doing the job of reducing my depression, although my fibro got some relief from it. Savella hopefully will treat my fibro even better, and help with my depression. I will post updates on my progress.

August 23, 2009 at 4:50 pm
(47) AP says:

CHECK OUT the web sites of FDA and webMD for side affects of many meds. There are many that report good and not so good thing about all kinds of drugs.

I was given a trial pack and I do not think I will take it. To many side a affects.

This drug was made in france in 1997, just aproved in USA this year Jan 14-2009

August 23, 2009 at 5:07 pm
(48) AP says:

Check out FDA web site and webMD for more reports of side affects on a person.

Doc gave me a trail pack and I will not take it due to the problems.

This drug was made in France in 1997, just made it to the USA in Jan 14 2009 aproved by FDA. For pain of FM.

August 23, 2009 at 5:41 pm
(49) pam says:

I am on my 3rd day of the trial pack of Savella. I am really feeling less pain BUT I have not slept in 2 nights
I already have trouble sleeping so this is really not good. But I did not have to take my Soma last night. I have had fibro over 20 years, since they fist called it Ebstein Barr Virus LOL. Name changed many times, symptoms never did! The pharmasist said it would cost about $140 a month in the gap period
of Medicare

August 27, 2009 at 3:49 pm
(50) Colorado says:

I am just about to start Savella for the first time and have never taken Cymbalta. (This doctor also prescribed Requip, but I only want to introduce one new drug at a time.) I’ve been on Lyrica for 3 years (Neurontin before Lyrica) and noticed vast improvement in the neuropathy in my feet. The down side is the weight gain and blurry vision. I’ve been on Oxicodone and a time release Morphine Sulfate to combat chronic pain.

For those who have ANY Rx coverage at all – you do not qualify for Patient Assistance via the drug companies. You have to have NO Rx Coverage WHATSOEVER to qualify. There are other programs out there.

For those on Medicare – there are 2 programs I know of through Social Security/Medicare. If you call Social Security or Medicare, you can apply for both of them over the phone (just have your last years tax records when you call – and if your financial situation has changed dramatically from last year, have income records from this year in front of you.) Don’t get discouraged if you call and get nowhere – call back and talk with someone else (they are confused over there, and persistence can prevail.)

I am interested in what #14 Reiser said about vitamin deficiencies (magnesium, B12, and vitamin D) and will pursue blood tests to see if that is an issue.

Also, I want to include a couple of things that help me. Hydrotherapy in water 90 degrees or above (hot springs/heated pool are ideal, but hot tub or bath tub help well.) Soaking – weightlessness is similar to the feeling of being in the womb.

Another help is Body Flex (isometric/isotonic stretching along with deep breathing) a 15-minute exercise program where you barely move and the emphasis is on breathing (similar to a yoga breath) while stretching. While the actual Level 1 video/dvd is lame, it comes with diagrams of each stretch and if you get the breathing down, you can watch TV or listen to music and follow along with the diagrams. Level 2 has a better breathing technique, but I prefer Level 1 stretches with Level 2 breathing.

Also, another exercise program that is helping me is Qi Gong or Qigong – an internal Chinese meditative practice where slow graceful movements along with controlled breathing techniques promotes the circulation of qi (our life force within the human body.) Meditation helps bring down the pain level and the combination of these movements and breath truly helps. I especially like the program Qi Gong: The Flow Continues with Lee Holden. This program aired on PBS, but can be found at his website.

Good luck all!

August 29, 2009 at 5:56 pm
(51) billy says:

I have had horrible, consistently worsening back pain for 9 years, I am only 36. I’ve been on Savella (lighest dose) for only 3 days and frankly I consider it a miracle drug. This has reduced my symptoms more than narcotic pain relievers, which I am happy to say I see myself easily being able to stop taking if Savella keeps working like this.

My only problem is a pretty severe nausea and sort of lump in my throat sensation. I hope those go away after time. I urge anyone with chronic pain to give it a try (believe me, I’ve tried all the rest – physical therapy, yoga, acupuncture, lyrica, anti-inflammatorys, epidural injections, 7 kinds of muscle relaxers, opiates, drinking the pain away, you name it). So far Savella works better than anything else!

September 1, 2009 at 12:09 pm
(52) Paula says:

Been taking Savella for three weeks and it has helped some. I did have bad depression the first two eeks but it has eased a lot now. My problem with it is diariah. It started off as an occassional thing, but now I am making several visits to the bathroom every day. I see my doctor this Friday and hope to get some kind of advice on this situation. Has anyone else had diariah on Savella?

September 3, 2009 at 8:06 am
(53) Jan says:

I have just started Savella 1 week ago. It is helping. So far, I haven’t noticed any side effects.

September 4, 2009 at 11:53 am
(54) Marion says:

I am only on my 2nd day of Saliva…I am scared to be taking it…due to some comments I read…
Besides my pain…which this is the first month that it lasted over 4 weeks…my mind feels foggy and my left eye is blurry..does anyone else have these symptoms of Fibromyaglia? I am only 39….my symptoms started 2 months after my bunion surgery…I was always healthy. I ran and walked….I eat healthy…..I feel so bad..because I can’t be the mom I want to be….

September 5, 2009 at 11:14 pm
(55) Maggie says:

Savella is one of the most horrible things I have tried in a long time. I too have had fibro about 20 years. I have been seeing a family practice doctor but was sent to the second rheumatologist. This one informed me she could only prescribe three drugs for fibromyalgia, Lyrica, Cymbalta, and Savella. I took the blister pack and started weaning myself off requip at the same time.
The vision thing happened to me. I didn’t pay any attention at first-thought I was just tired. And, I was downright Mean! I didn’t notice any particular relief from pain-did have more energy but it wasn’t a productive type.
I made a long list of reactions for the doctor, which she didn’t take and entered maybe six words on her little computer. Probably it was “patient could not tolerate drug”
Constipation was horrible. There was also a loss of other bodily functions that started slowly.
Something I don’t think doctors really associate with this disease is the anxiety. I wouldn’t call it depression, either. This last doctor suggested I “read up on fibromyalgia” She didn’t take into account that I have Lived fibromyalgia.
I have taken neurontin before and it had the same effects in a way as this drug only smaller. It just did terrible things to me. Nightmares are frequent.
Unlike some, I am only rx’d tylenol 3, ambien, lorazepam. I am made to feel like a real drug addict about it, too. This last rheumatologist made me feel more like a drug seeker than someone who really had pain. And, she could only offer me the three drugs above as an answer. She gave me a trial pack of Lyrica but told me if I had no success with neurontin before, this drug was much the same.
When I was taking the requip I didn’t notice that much relief from pain or spasming but at least I slept better at night. The more Savella I took the more seized up my muscles felt.
Whoever mentioned the drug reps flying in an out are right. And the companies are blitzing the doctors with encouraging news that doesn’t necessarily hold true.
One thing that has helped in the past is plain old phentermine. Talk about a maligned drug. It’s mention will usually get you a big old lecture on how it just gives you more energy. Not so in my case. I have noticed a significant help in pain from it. And, it helps with the brain fogginess that fibro seems to accompany.
Take Savella carefully and keep a journal. Some of the side effects are very slow but not good in the long run. Writing down how you feel each day is sometimes more helpful for you to look back and see how you have changed.
I’m glad some of you are helped. It’s good to know that some people are being relieved.
I, for one, am very tired of being treated like a drug seeker when relief is all I really want.

September 8, 2009 at 4:49 pm
(56) Joy says:

How long does it take to start feeling better? I am on the 11th day of Savella, and this is the worst I have felt in years! This summer,I was on a great combination of Cymbalta and Provigil. It was the BEST summer I have had in 12+ years. Then, I lost my job benefits and had to switch insurance. This company will not cover Provigil as it is “not medically necessary”. If I thought I would eventually feel better on Savella, I would be more inclined to keep taking it. As it is, the pain, nausea, fatigue, poor sleep, anxiety, and irritability are making it difficult.

September 13, 2009 at 9:24 am
(57) Jan H says:

I’ve been on Savella about 4 1/2 months. The first three weeks were horrible with nausea, sweating, and had trouble swallowing. The 100mg dose didn’t do much for me so my doc raised the dose to 150mg. Pain almost completely gone! I was down to only an occasional Vicodin instead of the daily max I was allowed. I’m also on a large dose of Neurontin, Ibroprofen, Flexeril, Xanax, and Klonopin for sleep. Reading here, some of the feelings I’ve had over the course of the last few months — worsening depression, irritability, sweating for no reason, etc. — may have been coming from the Savella; it’s so difficult to tell when you’re on such a cocktail of chemicals. It doesn’t matter now because all of a sudden my insurance refuses to pay for Savella and I will be going back to Effexor. I’m very upset and hope the pain doesn’t return to it’s pre-Savella level!

September 14, 2009 at 1:08 pm
(58) lt fms says:

I was diagnosed with fibro in 1995; I’m sure I had it much longer than that. Some days are better than others and Ive had several flairs where I could not work/function during these flairs.

My GP gave me the 2 week pack to try. after almost finishing it my BP has went up, night sweats, headaches (almost migraines), nausea, and depression. I’m stopping; another one to put on my do not try list.
I have tried so many prescription drugs with bad side effects that I am leery of them and starting to feel like Im a guinea pig for the drug companies.

I can’t take pain pills due to allergies so it is back to sleeping pills, massage, vitamins (B complex, B12, D, Mg, E, C, and fish oil), and hot tubs/springs. These are the only things I have found that help to some degree. Otherwise its live with the pain and try to smile. (even though you want to cry)

Best of luck to all; I hope some of you get relief.

September 18, 2009 at 3:56 pm
(59) Steve says:

What does Savella Cost for a 30 day supply of the 100mg. dose? I have insurance so I don’t qualify for the prescription company programs, but it doesn’t cover Savella.

Thanks,

September 20, 2009 at 12:16 am
(60) beth says:

To #40 (I believe your initials were DD). You are in Michigan and looking for a doc. I live in Northwest Indiana, just south of I-80/94. There is a doc in Munster, Indiana, H. Alan Jones, DO., 219/836-9515. He treats Fibromyalgia and is using Savella. I also have FM and has just started a sample of Savella 6 days ago. I am guardedly optomistic. I got really excited with the Lyrica and then was allergic and really was upset so I am not getting my hopes too high but I wish you good luck and I hope this helps. God Bless.

September 23, 2009 at 12:44 pm
(61) margie says:

Ihave had fibro for along time .Got a sample from my Dr. I had a very hard time with it, alot of side effects.I am still taking half 25+25 . Iam still very sick. Not sure where to go from here. m y Dr. is no help.

September 23, 2009 at 1:23 pm
(62) margie says:

savella cost 139.00 for one month.

September 25, 2009 at 8:20 pm
(63) Rebecca says:

The cost for Savella in my area is $130.46 for a month….so far so good was really worried I would not get any relief but have side effects but so far so good…..I am getting up easier in the mornings which is nice….the aches have eased off….they were driving me nuts….so its nice to have some relief….I only hope it continues….
God bless you all!!!

September 26, 2009 at 3:02 pm
(64) Kathy says:

Started about 5 days ago on the trial pack and feel the difference already. Much less pain at night and more energy during the day and much peppier in the morning. BP was fluctuating but seems to be leveling off. Flushing and sweating bothers me but if I can live without pain I’ll sweat. Man I hope I continue to feel this way, cause I’ve tried everything else with no relief. I think I’ll be able to take less pain meds and knock off tizanadine at night. Good luck to all.

September 27, 2009 at 10:31 pm
(65) Lora says:

I started Savella and on day 8 I am having very strange dreams like nightmares. Has any one else experinced this?

September 30, 2009 at 10:47 pm
(66) Jennifer says:

I have been on Savella for two months. I feel better than I have felt in nearly 5 or 6 years of terrible muscle spasms and pain. I do flush and it is uncomfortable, but it is a much more tolerable issue than not being able to move and function like a person. I am 36 years old and a teacher. I cannot afford not to be able to move. In addition to the Savella, I am taking zanaflex, a muscle relaxer and a does of Naproxyn , the muscle relaxer at night and the naproxyn during the day. My energy level is so much better, and I feel happier than I have felt in a long time, AND I feel like doing things, which is really wonderful, because I enjoy doing. I have lost nearly 10 lbs since starting the Savella, as it made me very nauseous and killed my appetite, but that’s ok too. I am a healthy weight for my height, and my appetite is returning to a certain degree. There has definitely been some adjustments with this medication but the trade off has been far less muscle pain and spasms from fibro. For those of you looking for a break from the terrible pain of fibro, I wish you much luck and I hope it works!

September 30, 2009 at 11:04 pm
(67) AIM says:

I just started Savella 50 mg twice daily. I was on lyrica 75 mg twice daily, then 150 at nigth time. It did not help me at all. I have MS as well as Fibromyalgia and Arthritis. I take other medications because of my MS but, I honestly have to say that as soon as I took the first pill of Savella I started noticing an immediate relief all over my body, from my spine, neck and legs. I felt normal, the way I used to be before my diagnosis, pain free. It took a while for my medicine to be authorized, I am on social security and AARP. Some of my medications my insurance do not pay for them, so I take them to Walmart and I pay cash for them, just $10.00 for 3 months!!! on some of my meds… Good luck to everyone… let’s hope that this medication will do us good.

September 30, 2009 at 11:23 pm
(68) PAW69 says:

Hello, I’ve had Fibro. for about 15+ yrs. Been on every med possible known to man for the first 3 yrs of diagnosis. None of them worked. So I just bit my tongue and went on in life with no meds what so ever. I start Savella and Lyrica tomorrow. All of these side effects y’all speak of, I already have and that’s without meds. So I’m kind of wondering, since I have all the side effects y’all speak of, without taking any meds, what’s it going to be like when I do take these meds? I have migraines everyday,ringing in my ears non-stop,nausau,sweats,can’t sleep,I cry a lot but that’s due to my husband being in Iraq until August of next year. So I’m kind of wondering, Should I take these meds? I see a psych for meds, Ambien and Xanax, But I haven’t even taken those meds at all yet. I have a phobia for meds I think. After all the heck I went through when I was first diagnosed with Fibro. 15+ yrs ago, I hate taking meds, they never worked and they made me gain terrible weight that I have faught since then to get it off. I saw my blood work and all of that is normal, B12 and all, that was mentioned earlier, those are all normal on me. He is checking Thyroid though and diabetes. In the meantime, I don’t know if I should go get these meds. On post does not carry these meds, So I have to go to Walmart and I don’t know if TriCare Prime will pay any or all of it. I don’t want to waste money on something that may or may not work or make me feel a lot worse than I already do. I had high hopes for these meds until I read the posts. Help please….

October 2, 2009 at 5:45 pm
(69) Kathy says:

I have been on Savella for about 1 week and a half and when I started side effects of HBP and constipation were bothersome but they went away. I did have some skin itching and told the DR. He said that would probably go away. Well no such luck. I started the next level of 25 mgs 2 times a day and the itching got much worse. I called his office and I’m now off the drug. I don’t know what’s next, waiting for DR. to call back. Anybody else having this side effect? I really had positive pain relief from Fibro and back pain and I even lost a little weight in the few days I’ve been on it. Will post the next step and soon as I get it.

October 4, 2009 at 2:58 pm
(70) Margie says:

I took one month of savella. The last two days I got very dissy and had trouble breathing. So I stoped taking it. Saw my Dr he said he had 15 people on it and they were doing good. So I took 25+25 hoping to work with a lower amount. In a few days the breathing problem came back. This makes me back of from the savella. Fibromyalgia ia something they do not know alot about.So when they come with a medication, it makes me wonder, is this really going to help.I would love to have some help with this.But all the side effects of this drug makes me back, A Dr long time ago told me to be carefuul of all the drugs the want to give you . So I have. I see so many of you on so much drugs.Iwould never take all that. I have had fibro. for 50 yrs before they knew nothing about it.

October 4, 2009 at 11:32 pm
(71) PAW69 says:

I’m on Day 4 of Savella & Lyrica. Going on day 5. The only 2 problems I have now is the headaches, which I use Head-On Migraine for and it seems to work well, and I feel like I’m wearing shorts of pain. my upper thighs and mid section have pain if I sit too long. Other than that the pain in my feet and the rest of my body seem to have subsided. I also take Singulair and Symbicort for my Asthma. It’s working so good for me. And the ringing in my ears are almost gone. But I’m not ready to put in a rating yet. It looks like my Dr. is going to keep me on 50mg twice a day once my starter pck is gone. I hope this works for me. I’ve gone so many years with not taking anything. I’ll let you know how it goes when I start the 50mg from the starter pack late next week.

October 7, 2009 at 5:02 pm
(72) Becky Craze says:

After reading the comments on Savella I am reluctant to start it. I got queasy just hearing some of you say it made you dizzy…I also have Minears Disease. My doctor gave me the script yesterday. I could not take the Lyrica or Neurontin. I am taking a B-12 shot once a month and 50000 units of Vitamin D once a week. I take Mirapex for my legs at night and use Ultram for pain. Right now I am in a major “fibro spell”…it is discouraging because you never know if you are coming down with the flu or it is the fibro.

October 8, 2009 at 10:01 am
(73) Tina says:

Hi all, just started Savella yesterday. My Dr. gave me the 2 week titration pack.

October 8, 2009 at 11:03 am
(74) PAW69 says:

Tina? A 2 week titration pack?

Okay, I was given a 4 week titration pack (28 days). He’s also keeping me on the 50mg after the pack is done. But my Lyrica went from the starter (don’t remember the mg) to 150mg. And the doctor told my I don’t just have Fibro, he said I have Acute fibro, and due to me going so many yrs without meds will do 1 of 2 things, It will either help me a lot or not at all.

I am on the 50mg savella and 150mg Lyrica now.

I feel weird,yes. I feel tired once in a while. Dizziness is light. BUT!!!, The pain is gone, I don’t feel it like I use to. Now I will tell you this, when I sit too long it kills my midsection (especially my hips). But I can get up out of bed and walk right to the bathroom instead of moving 1 mile an hour. I was told by the pharmacist that his wife is on the exact same meds as I am, She went through these side effect for the 1st month and a half. After that she was fine. She’s been on it since it first came out. She only takes the meds at night at bedtime now. So if we can just get through the first month. I think we’ll all be okay.

October 9, 2009 at 10:42 am
(75) Maria says:

I Maria was told by my physican that I have Fibromyalgia. I am only 34yrs old. I sympathaize with everyone who has it. Like a lot of u guys I visited the ER several times this month and finally I was diaganose . I am on my third day of Savella I pray it works because I am tired of all the Vicodin and other pain meds I’ve been on. Neil buddy I know u are 20 yrs old and u were dealt this card at an early age. I feel u pain u and everyone that has this diesase. I just wish there was more they can do for us. I want to run in the park with my 11yrs old and my 3 yrs old daughter.I cry when my 3yrs wants me to carry her up the steps and I can’t.What she doesn’t know is that I can’t even go up the steps sometimes by myself. I am tired of being sick but I try to keep my head up. We have to take it day by day. Please exuse all the misspell words.

October 13, 2009 at 9:37 am
(76) Isabel says:

I was diagnosed several years ago. I was prescribed lyrica and it worked really well but after a year it stopped working, I felt my fibro got worse. I then tried cymbalta and I thought this is a miracle it took all my pain away I felt I could run a marathon again……but then the side effects kicked in, I was up all night….insomnia. I just started savella we shall see how this goes.

October 15, 2009 at 1:38 pm
(77) Rebecca says:

Hey Everyone!
Just an update!! So far still so good!!! No aches!
I began to have terrible headaches and I thought I would quit my birth control pills to see if maybe it was counter reacting…and yes sure enough the headaces have stopped……I really want to stay on the Savella its nice to have no aches….so today that’s the plan….still not a lot of energy but things are looking up for me….
God bless you all!

October 18, 2009 at 12:01 pm
(78) Shirl says:

My Mom has Fibro. and started taking Savella she had been doing okay said she felt ok so far. She had been feeling like some thing was shocking her all over in different parts. She said that the shocks were less and gone at times. However now she is up to the 50mg tabs and now she has no energy, cranky, she got sick and vomited, & lastly she is having trouble sleeping. I don’t know if the symptoms will go away after her systom gets use to it or if she wont be able to take it any more. I was wondering has anyone else felt this way as well and if so did the side affects get better?

October 19, 2009 at 11:53 pm
(79) amber6363 says:

yes ive been suffering from fibromyalgia since the age of 13. i am 29 now. savella is the first drug that i jhave felt such tremendous results sooo quickly. i do find that it is making me very nauseous right after taking it.

October 22, 2009 at 2:08 pm
(80) flo says:

ive been in pain for nine yrs ,been on savella for 3 wks and im feeling a little more alert and starting to do some things without not as much pain

October 23, 2009 at 6:39 pm
(81) Rebecca says:

Dosage? Is 5omg in the morning and 50 mg in the evening the highest you are suppose to go….sort of feel like I am not doing as well as I first was…..guess I better call my dr… is anyone taking any more than that?

November 1, 2009 at 1:06 pm
(82) Sandy says:

I have had fibro since I was 15 but was told then it was growing pain.now I am 31 and glad the pain isn’t “in my head”. I am scared of Savella now after reading everyones side effects! I have been on cymbalta and lyrica for a year with less pain but gained 35 pounds. My doctor gave me a trial pack of savella. I can tell such a difference being off my usual meds.I hope it gets better. Maybe the weight gain was not that bad!

November 2, 2009 at 8:39 pm
(83) Irene says:

I’m another long-term Fibro sufferer. I was 1st diagnosed 20 years ago, but had many of the symptoms for the previous 10 years. For most of the time, we’ve used various pain-relieving drugs, some never worked at all and some helped some of the pain for awhile (6 mos. to 5 years). Cymbalta was not a good drug for me. Lyrica was immediately terrible for me. Do have the Vit. D shortage and am up to the bottom of the ‘normal’ range, but it didn’t relieve the FMS. Have been taking Savella since June-took the sample pack @ half-dose, and then gradually increased up to a full dose-about 2 months, but have received a lot of FMS pain relief after the 1st 6 weeks or so. The high BP is the worst side effect for me, and am now taking a lot of other meds (with side effects of course) to try to combat that. The vision and dizziness are concerning, the ‘hot-flashes’ and sweating, irritating. The FMS pain relief is wonderful, but find the arthritis pain and FMS ‘brain fog’ continues. My pharmacy charged $122.00 until they got Medicare to pick up a good part of it-I pay 40.00/mo. I retired a few years early and finally got medicare last year. I think it is a drug that should be given a good try-at least two months before deciding whether it will work for you or not-and if you can tolerate the side effects. For most of us FMs sufferers, side effects are the name of the game!!!

November 5, 2009 at 11:27 am
(84) Amy says:

I, too, am having some weird symptoms with the Savella. I did the 2-week titration pack while coming off Cymbalta. I am at 2 1/2 weeks with Savella now. I am having severe diarrhea, weakness, dizziness, and last night, I started having trouble breathing. This morning, I feel like someone is squeezing my throat shut (not anaphylactic feeling, different). Talked to doc earlier in week and they alread knocked me down to 25mg once a day. I had no luck with Cymbalta. On it for three years and all I gained from it was 50 pounds. Tried Lyrica for 6 months…I have no memory of that six months, I was a drooling zombie. And no pain relief whatsoever from any of these, just bad side effects. Has anyone else with fibromyalgia noticed that they don’t do well with ANY medications, i.e. they don’t work the way they do for “regular” people and you have crazy side effects?

Also, I would just like to remind everyone to check possible interactions between new prescriptions and the ones you are already on. Even if the same doc prescribed them all for you. I noticed one person said they were already taking Ultram and were starting Savella. These two should not be mixed, and don’t trust the doctors to check or care. I always come home and use and interactions checker on the web before I fill my prescriptions. I’ve even had pharmacists tell me, “You can’t take these together, I can’t ethically fill this for you.” Makes my trust in docs plummet.

November 24, 2009 at 8:09 am
(85) kathy says:

been on savella 2 months and has really helped with pain, stiffness, and loss of energy. This last weekend went to Big Bend and did a lot of hiking! After the first day was afraid that I would not be able to move, but I felt great!
As to side effects, nausea went away after a couple of weeks when I first started meds, sweating was terrible–it is gradually decreasing, main problem is gas and constipation. Hate taking stuff all the time for this. Any ideas?

November 24, 2009 at 10:06 pm
(86) deb says:

I have been on Salvella 5 weeks now and so far am happy with it. The brain fog was always more concerning for me (it was really bad), it is 95% better now. The pain is much better and my energy is way better, I feel like I can function now. My side effects have been nausea, dizziness here and there, headaches (they feel like sinus headaches so Im not sure if its from the meds, but I think so)most of them have subsided. There was a couple times I didnt take the doses I was supposed to and started feeling the pain come back, so Im sticking with it as long as I can.
Can anyone out there that has pain in you back expain what kind of pain it is for you. the reason I ask is I broke my back years ago and Im not sure if its that or the Fibro. I cant stand very long without it the pain starting.
This is such a confusing condition, so many people have differant symptoms.
Good luck to all!

November 26, 2009 at 7:18 am
(87) Faye says:

Hey Lisa
I just started savella about a week ago and other than the headaches which are common I already like it better than Cymbalta. Cymbalta made me feel weird and it seemed the higher the dose the weirder I felt. Cymbalta also put extra weight on me and another side effect of savella is possible weight lose. Here’s hoping!!! Anyway good luck as we all know all we can do is hope right.

December 1, 2009 at 8:03 pm
(88) Maggie McK says:

I’m so grateful to everyone who took the time to comment…first time I’ve seen your comments. I’m so thankful to read them as I decide if I will or won’t try savella…I am struck most by what wonderful, kind people get sick with this crummy disease!!!I’ve been sick with FM &CFS since mid-80′s..have wked in patient advocacy and know we will not get our answer until all of us get involved, demand that our govt. put more resources into this. Meantime, remember how special you are and how everytime you reach out to others you help. Thank you for helping me, being there, tonight. Peace,advocate and wishing you better health in 2010

December 10, 2009 at 12:19 am
(89) Glenda says:

I was diagnosed with Fibro 5 years ago. Have basically tried everything that most of you have mentioned in your posts.Nothing seemed to really work for me. My rheumatologist let me try Savella and I had high hopes that it could/would provide me with some relief. It did not. I recently found a D.O. in Fort Worth,Texas that I am seeing for Natural Bioidentical Hormone replacement therapy.When I mentioned to her that I had been diagnosed with Fibro, and everything that I had tried without success, she asked me if anyone had ever prescribed for me low dose Naltrexone.I had never even heard of it before. Higher doses of Naltrexone have been presecribed for years to treat opiate addictions, alcoholism, etc..But, the low dose Naltrexone has been used in clinical trial studies for Fibro sufferers, with great success. So, I agreed to try it and have been amazed with the results I’ve had. My pain is gone for the most part. Feel better than I have since being diagnosed. The low dose Naltrexone has to be compounded, however, it is so inexpensive, as it is a generic. When I saw my Rheumatologist recently, I mentioned to him that I was taking the low dose Naltrexone and was having fantastic results with it. He become somewhat agitated and told me that it had not been approved by the FDA for treatment of Fibro, and that he WOULD NOT prescribe it for me. I told him that was fine with me, I would just keep getting it through my doctor in Fort Worth. After that visit, I think it was about three days later, I received a letter from him saying that it was time to end our dr./patient relationship.All I can say, is that I wish I had been able to find my D.O. in Fort Worth five years ago.I swear by the low dose Naltrexone. Google it and read about it, and see what you think about it. I love having a doctor that thinks outside the box and is not bound to only prescribing FDA approved treatments. I have to drive three hours ( one way ) to see her, but it is more than worth it. I hope everyone that reads this at least considers giving LDN a try.It has been an answer to my prayers.My blessings to all of you who continue to search for some relief.

December 15, 2009 at 11:20 am
(90) Tamara says:

I got two sample packs to try. I thought “how will I ever know in two weeks”? I, too, have been taking Cymbalta since it began and it gave results that were passable, at best. Today I took the FIRST FULL DOSE of the morning pill. Even on the ramp up I seem to feel less pain…. alot less. I didn’t even realize how much less until I started reading all of these comments. I am a Lymie. I acquired my fibro as a shadow creature to post/chronic Lyme Disease. You can read the whole story at my URL listed or google airllusion. I have a small taste of who I used to be. I am VERY SCARED to surrender to it. But, then again, I will enjoy the moment and embrace the break from constant pain. I still have daily headaches, but I have a golf ball sized polyp in my sinus, so I’ll accept that. My doc left me on my Cymbalta (60mg/day). I have also changed to drinking 95% water and very little aspartame with nearly no caffeine, so that can help? I am also taking Neurontin (400 mg 3/day), Flexeril (10mg 3/day), Benadryl (50 mg/bed) and Symbicort (160/4.5 2/day) for anyone taking these too. I’m holding hands with you all and focusing on the positive!

December 21, 2009 at 11:33 pm
(91) Tamara says:

Glenda…. I have one of those letters from a doc too, screw em. It’s OUR body. I drive 300 miles to go to the clinic for $10 twice a year and my mom picks my meds up for me every 30 days. YES, it’s worth the drive. I’ve been happy with Savella so far. Might have to get a script for it. Filling out a ton of free and med assist proggies now too. Luck to all and happy holidays!

January 6, 2010 at 2:18 pm
(92) Cindi says:

Having been on Zoloft, Klonopin, Synthroid,Tramadol and Ultram, I just met with my Dr 12/31/09 and started the Savella trial pack. I felt a difference within a few days. I am on day 7 and half way thru. I am crossing my fingers that I will continue to feel better as the dosage increases. I may even be able to stop using Tramadol if it works over the next month or so. SO far so good. Thankyou Savella inventors!

January 6, 2010 at 2:27 pm
(93) Cindi says:

ALMOST FORGOT-lol
I have tingling lips,feel slightly buzzed and have dizziness, but don’t care because most of the pain is disappearing.
I cry easily right now, but expect that is from changing from 200mg of Zoloft a day for years
to 12.5mg x2 a day then 25mg x 2 a day and next is the 50mg tabs x2 a day of Savella. I have only felt nausea once or twice, so remember to eat something first.

January 18, 2010 at 2:14 pm
(94) Deb says:

1st time on this site. I started taking Savella last month. After reading other comments I don’t feel so lost. I have had most of side effects stated, dizziness (hope it stops soon), ears ringing, nausea (stopped now). Others are muscle cramps worse, coughing and asthma worse. Don’t know if it’s because of the Savella or weather or environment on the asthma though. The sweating has finally lessened. I’ve been on Lyrica for a few years and have not noticed much of difference in blurry vision. Oain and fatigue not much better yet. God has been a real help in my life, couldn’t go thru this without Him. Post again later. Thanks 4 all ur comments.

January 18, 2010 at 3:21 pm
(95) Hayley says:

I have osteoarthritis ,major muscle and nerve damage and 2 years ago had a full ankle reconstruction including, I have also broke 23 boneshad a full ankle reconstruction w/ a a cadaver bone graft and screws .Obviously I have been on every pain killer there is at the worse dilaudid, valium and morphine, 2 years after the most recent surgery in 2007 I was put on cymbalta, valium and mobic …It was magic , The 1st few weeks were alot of bad side effects from the cymbalta a little speedy nausea , heavy mid day nap, but after I got used to it my appetite was alot less and it stopped all my asthma symptoms I am guessing from the norepinephrine uptake I have had severe asthma bronchitis which has been a result of my chronic inflammatory problems.My dr. was out of cymbalta samples it’s dreadfully expensive . So i tried Savella with mobic it’s really good too

January 18, 2010 at 11:05 pm
(96) hayley says:

I have been own the sorta once a day dose of savella, but I am noticing one day I didn’t take it felt weeepy and depressed and after increasing the dosage I have more food cravings that are specific and blurry vision I have been on it one month now .I have cold turkeyed cymbalta with no side effects , but both have helped the pain and accompanied by mobic and valium have nearly elimated it . However I am thinking I perfer cymbalta and managed to stay on 30 mg for a year fine as long as it was taken with mobic

January 18, 2010 at 11:15 pm
(97) hayley says:

I am findind this all so interesting I may add I am a sports and injury rehab therapist.I use alot of hydrotherapy treatments and the extra important thing I may add with these suppliments watch your iron and take extra vitamin c {like e-mergency} and a multi b suppliment with e and coq enzyme.When the nerve pain is out of control I have done vigorous salt scrubs or resorted to morphine and can’t get out of bed. But so far the savella has given me more energy and no pian at least minimal bu tyou can’t stay on the samwe dosage as you can with cymbalta..I am gonna use of the sameles I have 3 monthes worth and have been on it 1 month , but I think I may go back to cymbalta

January 19, 2010 at 9:03 pm
(98) katie says:

Wow. An online friend told me about Savella today and I’ve been fascinated by all your experiences. I was diagnosed 25 plus years ago and other than bad experiences with Neuronton and Lyrica I have never been given any pain medication for my FM. I’ve worked on my own with water therapy(I instruct,too) and easy aerobics and light resistance training. Savella sounds promising but if I pay my monthly premium I won’t have the funds left over for another expensive script and on paper I have too many assets for any company assistance. Reality is another thing altogether. Good luck everyone..it really isn’t a one size fits all syndrome and so many times other conditions overlap.

January 20, 2010 at 12:50 am
(99) Joyce says:

I am starting on Savella and just ended 2 mos. trying Cymbalta. My main problem is depression, but also have fibromyalgia for 15+ yrs. I was on zoloft for yrs and then about 2 yrs. ago it started to lower my heart rate to the point that a pace maker was talked about. Now trying Cymbalta, along w/ the worst headaches (sinus-like) I’ve ever had, it also dropped my heart rate to under 60. Mine and my Drs. conclusion is that I am sensitive to serotonin uptake (SSRI’s, SNRI’s). The difference w/ Savella is this: Cymbalta affects serotonin and norepinephrine in 3 to 1 ratio, whereas Savella ratio is 1 to 10 (1 serotonin,10 norepinephrine) so hardly affects serotonin at all. Dr. said it will give me energy and is a very safe drug. For a lot of you on multiple meds. sometimes you have to go off all and then restart one by one to see the full effect and know for sure wich drug is causing the side effects. I’m hoping the Savella works on my depression and my fibromyalgia, even though not approved yet in US for depression, they do use it in Europe for depression. I also watched a series on our brains which says that depression shrinks your brain, but antidepressants help to rebuild damaged areas. This could be good then, instead of more damaging right. I also had the vision problem on cymbalta.

January 20, 2010 at 2:56 pm
(100) hayley says:

ok so in the morning savella does make my eyesight blurry , and it turns out I am becoming really snappy at people , however I can do alot more physical labor than I have in 2 yrs.I have 12 cymbalta brought from mexico and looked at an online thing for canada .I have no insurance because I am self employed.I took the cymbalta today much less irritable, with valium and mobic and am swimming as therapy with hot soaks on the spot with nerve damage. It’s hard being a sports and injury rehab therapist and dealing with an issue so new to me when I work with people I can shut off how much pain I used to be in ,however I did 12 hrs of massage in a week.I am not in pain now , but wow one day off savella was bad .With cymbalta I don’t have crash weird emotions…Also for everyone here I hate to promote Walmart , but without insurance the mobic is only $4 for 1 month and valium $16 for 90 pills, cymbalta $160 per month ..at cvs or wallgreens mobic was $143, cymbalta $60 per pill, and valium $60

January 24, 2010 at 1:25 pm
(101) Marie says:

I take Lyrica 200mg and Gabapentin 300mg with cyclobenzaprine and xanax. My DR thinks savella will replace all these as it makes me dizzy and bad for work. I tried Cymbalta and was extremely sick for 2 weeks and suicidal so I am leary to try Savella. At the same time my current treatment is not working well and I am down to 2 days off left at work and desperate. Are there any tips for the side effects? I will have to work no matter what is happening. I also have a bizarre sensitivity to light and Lyrica was the first thing to help that. Does anyone else have this sympton? Thanks..

January 28, 2010 at 2:23 am
(102) Keplington says:

Too many “feeling sick” comments. I’d rather stay away from these crazy drugs – Lyrica or Cymbalta or Savella. If fibromyalgia is my problem, why do I need anti-depression and anti-epileptic drugs?

Well, I’m happy my fibromyalgia is in remission because I know depression has nothing to do with.

The fact is, SSRI, NSAIDs, and calcium channel blockers are the worst drugs with side effects. Research has found that ’5% of hospital admissions (1 million/ year) are the result of drug side effects’. Read the facts…you will be shocked…www.wnho.net/deathbymedicine.htm and http://www.ibetes.com/attachments/Hnat_Endorsement_for_Mirac.pdf

January 29, 2010 at 9:49 am
(103) chris says:

my soon to be wife has had fibro since she was 16 and i have had arthrits since i was 12, the most effective combiation for my fiance is savella and low prosessed sugars and low gulten she has done this for 4 weeks and only has had to take her pain meds 3 times and also has had less mucsle spasms, the best treatment for both of us has been cannibus IE marrijuiana

January 29, 2010 at 10:51 am
(104) skoolzone says:

I for one am tired of being a crash test dummy for the drug companies. I am also a medical marijuana patient, and i find that it helps with the everyday pain i get. Still have to take pain meds when a bad flare up occurs. But hey drug companies cannot profit from something natural , so it will always be illegal.
genesis 1:29 – 31

February 1, 2010 at 8:43 am
(105) Bryan says:

I have fibro. I am very active at work. I’ve been on Ultram, and bad flare ups Vicodin. Dr wants me to go on Savella. I did try Cymbalta, it was horrible emotionally. Savella was similar to cymbalta.

I had horrible headaches, I cried, emotional mess. I’m not the emotional type. It helped some with the pain, but the nasty mind fog, and emotional issues, I will never take it again. I flushed the script.

February 7, 2010 at 5:40 pm
(106) doshia says:

11 it lasts day nausea is gone if eat first.i have all kinds of energy.hope and pray every day

February 8, 2010 at 11:39 am
(107) Kara says:

Just starting day 4 of Savella for FibroM — So far, so good! & had no pain following very first pill. Just went from 12.5 to 25 mg, & started feeling funny. Now, I’m thinking, this is definitely a wonder drug, but do we need more than 12.5 mg? I may start splitting the pills in 1/2, & just not go any higher. Why rock the boat? I’ve had to continue taking Flexeril though to get the muscles not to knot. The one night I skipped it, I did have pain the next day, but the 2 meds together seem to be doing the trick! Just scared to go higher.

February 8, 2010 at 5:16 pm
(108) Jonathan says:

I have had mysterious pain for the last 20 some years. I was finally diagnosed with Fibro about 3 or 4 years ago. My doctor suggested a study drug – tuns out it was Savella.

I have been on 200 mg morning and night. I feel fine and have had little side affects. I remember having issues with dizziness, but it went away in less than two weeks.

I am currently on the study drug to find out long term use problems. Actually I would not give up this drug for anything. I have my pain down to a manageable level. The one side affect that I am having trouble with is fatigue and depression. However I am not sure that it really is the drug. I have been out of work since November of 2008, my wife and I are going through bankrupsy and we may loose our house of 15 years. So I think that a little depression is to be expected.

I have attended workshops where the topic for discussion was Savella. Not everyone takes to it, and it tends to polarize people. You either love it or hate it.

For those of you who other meds work for you, don’t add another one just because it is available. go with what works. Life is too short.

February 17, 2010 at 9:35 am
(109) al says:

I just started taking Savella from a tritration pack, by the time i had increase the medicine to 25mg-50mg. I had much better days..I now am taking 100mg. I have had “normal days”. I forgot what i was like to be without pain. I still have stiffness and some pain, but not like it was.

February 19, 2010 at 10:36 am
(110) Kathy says:

I just started the pack yesterday. That first pill last night put me straight to sleep. Although I woke up with the regular aches and pain I was happy. I havn’t been happy in a while. This my help the 20 something that has been diagnose with fibro. EXECRCISE IS IMPORTANT!!!!! As I look back there was a time where I did not have any pain and that was the time when I had gotten into this health kick and was lifting weights. 6 kids later it’s been hard to get back to the lifestyle but hopefully with Savella I could be half the person I was back then.

February 22, 2010 at 4:28 pm
(111) Cathy says:

started savella 1 week ago, Feel wonderful. My energy level is GREAT. Having a side effect that I didnt not see anyone else mention. Was curious if any other women out there on this medication were experiencing the same. It has completely screwed up my monthly cycle.

February 23, 2010 at 1:22 am
(112) Kate says:

I am so happy for all of those who have found relief from Savella. Keep up the good work! I want to say that I am not writing to dishearten anyone or discourage you from tring it but I feel the need to share my experience. I have had fibromyalgia for 10 years. I’ve tried every treatment under the sun. Some worked for a little while but none of them really stuck, if you know what I mean. So when my Dr. told me about Savella I figured what’s the worst that could happen and gave it a shot. I’ve stuck with it for nine months and I’m sad to say that I have found no relief. Now I’m not sure if anyone else has experienced any of the RIDICULOUS side effects, but let me tell you it was a bitch for me. Since I started taking it I have had the worst nausea that I have ever experienced in my life. It was so bad that I began vomiting regularly to the point were I was at an unhealthy weight. I actually had to begin taking prescription nausea medication Zofran (usually intended for chemotherapy patients) just to maintain a reasonable weight. Also, it added to the insomnia and irritable bowel issues that my I already experienced from my fibromyalgia itself. Oh, and those “hot flashes” and “increased sweating”, or as I call them, ” Intermittent Infernos” and “Sweating like a whore in church” are ridiculous side effects for no relief. So I have officially begun to end the madness and am weening myself as we speak so that I can try something a little less horrible. So I salute all of those who do experience these things and endure through it. You all deserve medals or trophies for sticking with it. I hope that you all have better luck than I did with it! Stay hopeful everyone!

February 25, 2010 at 12:49 am
(113) Michelle says:

Hi everyone, I have had Fibro for 5 years, no insurance and no meds coverage, so untreated for most of the 5 years. Tried the Lyrica but couldnt keep up with the cost so had to abandon after 6 months, but did work relatively well. Started the Savella 2 week Titration pack today. Kind of scared of the all the side effects, but I am at my wits ends with the pain and no sleep, and sense of normal life. Doctor also gave me Flexeril and Ambien for the sleep. Confused that some say they are on Lyrica and Savella at the same time? Also someone said they take Amitriptyline with the Savella? I asked my doctor about that and she said it was not a good idea to mix the two, could do more harm then help. Hope it works as it seems to have for others, just scared of the nausea and bowel problems, have enough of that already. Will let you know in a week or so if it gets better of worse.

Thanks

February 25, 2010 at 1:17 pm
(114) hayley says:

So my conclusion after using both savella and cymbalta is this if I may be so blunt both stop the pain.I can’t orgasm on cymbalta , but have no side effects if I eat with it.Savella I can have great orgasms , but for 4 hrs after taking the drug I am nauseated , sweaty , and irratable and feel like I have a fever and blurry vision. They are interchangeable so according to my doctor .So I guess I must plan my sexual side effects anyone else have this?

February 28, 2010 at 1:05 pm
(115) susan says:

ive on my 7th day of savella and i cant hardly get out of bed without my husbands help. i continue to hurt while up when moving..seem i am worse since i stop taking cymbalta. dont know what to do, sa i cant stand the pain.

March 3, 2010 at 11:43 am
(116) Peggy says:

Having an orgasm on Cymbalta was tough but pain was completely gone and I felt wonderful. It was the best I’ve felt in years. Dr. has me trying Savella now. It’s been 2 weeks and pain is terrible but I can orgasm again. I will try the Savella for a month and if there is still no pain relief I have to go back to Cymbalta. Hubby will just have to understand.

March 7, 2010 at 2:00 am
(117) Amie says:

Hello All! I am so happy to have found you talking about Fibro and treatments for it. I was diagnosed 2 years ago after many years of being tested for so many illnesses. I was treated with Lyrica and Cymbalta until now. I found absolutely no relief from the stiffness and pain that prevented me from getting out of bed in the mornings. These drugs only made me sleepy and tired. So I decided to quit. I felt no more pain and stiffness than I did before I quit. Of course, I did the withdrawal thing– yes I did. Then a couple pf weeks ago I went to a lecture at a local hospital on fibromyalgia and heard about Savella. Being a drug skeptic, I was scared to take the stuff even though I asked my doc for it immediately. Today I was paining so badly and cried so shamelessly until I just decided to take the “begnning Savella pill.” I thought I felt better after a few hours, so I took the next one for today. I do feel better. For 2 years I suffered and I read other peoples stories, but I could never tell mine. I just didn’t feel like sharing my sadness and feelings almost like abuse by the hands of some of the doctors even my employer. My husband was indifferent and my adult children could not believe that I was asking them to help me with getting out my monthly bills and doing mu simple house chores. Now thanks to God who showed me Savella, tonight, I can at least talk about how much better I feel– if only for right now. I can at least put some of my thoughts in words without fogging out. I can atleast get up from the bed without grabbing my back. I am prayful that my legs and arms will not ache tonight, all night when I finally try to sleep. Sleeping has already been a problem, but I am hopeful that it too will get better, if indeed Savella continues to help me as I believe it has already. To Deb,who wrote comment #86, you asked if anyone has back pain with fibro. Oh yes I do! It is awful persistent pain for me. It is pain that starts somewhere in the middle of my lower back. It really hurts more when I sit too long with my legs down. That back pain continues down my buttocks– on the right side all the time and on the left very often. When I stand too long, my buttocks pain like crazy. I can bend foward without much increased pain but God help me if I try to bend to either side. I hope I encouraged someone tonight. Each of you have helped me with what you had to say. May God bless us all.

March 8, 2010 at 6:12 pm
(118) SUNSHINE says:

Amie your story has made me decide to give Savella a shot. I have been on it all and nothing has worked for extended periods of time. With Cymbalta the sweating was so terrible so I am worried about the same with Savella. I wold give anything to have a clear mind, less pain and enough energy to get me through the day! I have had the starter pack for over a week now and all the horror stories were making me very nervous. I was so nauseated with Cymbalta but hung on so I figure I can do it again. Thank you.

March 9, 2010 at 9:56 am
(119) Don says:

OK, some of you are getting me scared, but I have to try what I have to try, I guess. Lyrica really didn’t do a damn thing, you know except for giving me that gorillaish shape that I’ve always dreamed about. It got so bad that They tried me on short term hydrocodone, until they came up with this Savella. The problem is, it seems like the first muscle hydrocodone relaxes, is the diaphram. I did make me feel more comfortable, you know, except for the breathing thing.
I was given a pack yesterday, when I asked what to look for for the side effects, I was actually told, and I’m not kidding. Side effects are usually a psycho-symatc thing, if I was to be told, I would then start feeling them. So I took my first dose last night. Another bad night, but I’m used to that. I woke up, and felt like I had a head cold, So I gave in and looked up the med and sure enough.
Anyways, I also noticed that Cymbalta shouldn’t be used with Savella, but my doctor gave me the Savella and didn’t tell me to discontinue the Cymbalta. Don’t even want to go to the Dr on this one. Any opinions ?
Anyways I’m on day one, luckily, I’m on vacation for seven more days, however, when I return to work, I work with people with developmental disabilities, the podiatrist is coming out to do toenails, I know that doesn’t sound like a lot, but we do it at the group home and it involves about an hour to an hour and fifteen minutes of restraining (they don’t like their toes touched) Last time I ended up with a busted wrist, which meant comp. Which means nothing that is non-comp can be dealt with, until the comp is closed.
And of course, even though the Dr. did give me my entire 5 minutes of allotted time, he really didn’t understand my question of driving to work. Sure I can handle the blurred vision, except at this time of the year in New York, it’s still dark when I go to work, and to be honest on-coming headlights are terrible.
Good luck to everyone, and I hope to be able to type again, in the up coming weeks.

March 9, 2010 at 6:33 pm
(120) Anne says:

I just heard about savella and went looking for information…boy did I luck out with this board! Thank you all for all the info posted. But I have one major question that I haven’t found an answer to: I currently take 40 mg Celexa and 40 mg Prozac daily for depression…can I continue with these, wven if I need to decrease the dosages, or must I go off of them completely? Thanks

March 10, 2010 at 4:11 am
(121) terry says:

my sympathies to all who suffer with fibro. i have had it for at least 10 years and have tried many meds including lyrica. it made me so sick i couldnt eat. i even tried taking a nausea pill with it but, it still made me so nauseated. i have noticed i have become very sensitive to a number of meds since fibro reared its ugly head, (by the way, my sister also suffers from fibro and am pretty sure my mother had it but, was never diagnosed)we all suffer from some type of neuropathy but not diabetic. i currently take pain meds, muscle relaxers and sleeping meds. however, often i do not sleep regard;ess of what i take. some of you may also have this prob. if you do keep a log of the baromeric pressure. when it is rising i do not sleep sometimes for 24-36 hours. i am very hesitant to try savella and appreciate the input. i thin i will stic to what i am taking and avoid further adverse drug reactions. best of luck to all of you.

March 10, 2010 at 7:29 pm
(122) Cyndi says:

Oh my Goodness. I have hope I think now. I was given the 2 week tritration pack today from my Doc, Treating this for the past year or so and nothing worked. In pain everyday. The Booklet they came with the sample I could have wrote it word for word. Looking forward to not hurting so much, And having more energy and sleeping better. Basically everything I haven’t been able to do .
Thanks to all the notes on this site , it has helped. Sorry for all of you you haven’t had any relief. will say a big prayer for all of us. Thanks a heap!!

March 12, 2010 at 11:36 am
(123) Tracy says:

I’ve been taking Savella for quite some time – it works great. I’ve noticed a big improvement – though it does have side affects – but the pain is better

March 15, 2010 at 9:25 pm
(124) beverly says:

I started Savella two weeks ago and I came to the internet tonight to find out what the side affects are because I feel awful. I am nauseous, my jaws feel tight, I have terrible dreams, I am tired and depressed in a weird way. After reading other posts I now know it wasn’t my contact lens it is truly my vision being affected by this drug. I have had fibromyalgia forever, but the side affects of this are much worse. I just keep exercising finding a balance between pain and not so much pain….and stress is the worse thing anyone can have with fibromyalgia. Good luck everyone.

March 17, 2010 at 12:17 am
(125) Terri says:

Hello, I have had fibromyalgia for a couple of years. I was on so much pain med. that I was a walking zombie, could not be a mom to my 5 kids. It killed me! I finally go sick of being sick and looked for help outside of medical doctors, I found a chiropractor close to where I live. He not only speciaizes in chiropract care he helps you with your nutrition first. He had me do a 14 day detox. It’s called ultra clear. And was put on a very strict diet. I am mostly pain free and can be the mom I want to be. the only med. that I stayed on was lyrica, loved it but have gained about 40 pounds. So my family doc. put me on savella on day 3 and am doing just fine. I got my life back and my family got their mom back. I wish all of you the best, and don’t give up there is help out there.

March 22, 2010 at 10:31 pm
(126) Erika says:

I started Savella 5 days ago. The first few days were TERRIBLE – nausea, decreased appetite, very sleepy, headache (sinus-like), and stuffy ears…I also had the “zinging” sensations in my head like I did with Effexor…Has anyone else had the zinging? Kind of feels like bolts of lightning going through your head – it’s not painful, but VERY disconcerting…It is apparently common with Effexor, but I have not seen it listed as a side effect with the Savella.

The last two days have been much better…I haven’t been overly nauseous (have to take the Savella with food and no other meds, but a small price to pay) and I have had less pain and more energy. I am a 28 year old special education teacher and having fibro (along with more degenerated discs than healthy and a rod in my hip) makes it hard to enjoy my job like I used to, but today was better….If tomorrow is better still, I will call Savella a success.

Long story short for people new to Savella (and any other med) – try to stick with it…In my experience, the side effects taper off after a few days (sometimes 10-14) and then you can really see what the medicine does for you. Also, don’t change more than one med at a time – if you stop 2 and add 2 all at the same time, there’s no way to know what’s working and what’s just making you sicker…

March 27, 2010 at 4:08 pm
(127) Victoria says:

I am not totally convinced I have Fibro. It may be wishful thinking. I so want this to have an ending. I responded well to the Savella initially (working thru the sweating and nausea) but fell several days ago and since then my body feels like a million stinging needles are inside of me.
The only place I felt more of the muscle type problems initially was my low back/ spine area. When I was able to pay for PT, he explained to me about the Myofascia knots and I do always feel like I am being pulled in that area…like it is tightening up on me.
Here are my questions to those who feel you have gotten proper medical attention and you do have fibro….
I feel more electrical, burning, needle type pain than actual stiffness or muscle pain. I feel like my low back spine pain, the tingling, needle stinging pain thru out most of my body, and whatever it is I feel in my arms (which has progressed rapidly from a shoulder ache to total sensitivity to air and feeling like all the veins running thru them are cold and hot) are all different type sensations and pains. It has all changed so much since the initial diagnosis of myofacial pain…then fibro.
I do continuously have low D test results, I get B12 shots, and recently found on a bone density test to have bone loss in the areas that hurt continuously even on the “good” days.

How do I know I have fibro? What if this is something else related to the nervous system or nerve damage? What kind of doctors have the right knowledge and want to do more than take the easiest route and drug you up???
I am only 53 and led a very active life a few years ago. I had a very high pain tolerance. A series of things happened…and here I am…virtually no life. With fibro, do you feel sensitivity everywhere??
I knew someone who died after having been diiagnoised with MS 12 years prior. She actually had Huges disease and could have been cured. So many doctors blew me off for being a middle aged female, then I went thru the protocol of a natural doc for mycoplasma…nothing changed. Have high titers for EBV and CMV but supposedly there is no treatment for that. I have to live or die. There is no one to help me and I am now out of money.
Any thoughts about when to trust the diagnosis of fibro? Any thoughts about what other things I should ask to be tested for? I only have vision in one eye and either the meds or the constant inflammation are wreaking havoc on that one eye.
Thank you for any wisdom you can share.

March 31, 2010 at 12:12 pm
(128) terri says:

Ericka, I do know what your talking about with the pins and needles. my skin feels like its on fire mostly when i get over heated. I dont have a clue what to do about it i have to take bendryll to get it to go away. I am not taking the savila any more, I felt like I way dying yesterday it was like I wasn’t there. I was like that for 4 days. so it’s back to Lyrica and gaining more weight. I am sorry that most Dr. look at fibro. patients like we are crazy but something has to change, people cant live like this it well to be honest it sucks!!!!!!!!!!!

April 1, 2010 at 12:12 pm
(129) Colleen says:

I had a cervical spinal fusion done 3 yrs ago for a bulged disc in my neck. That surgery was supposed to cure my pain. NOT! Instead, my body went crazy from the steel plate and screws in my body. My body is in fight mode constantly. The pain is EVERY day ALL day. I have tried every drug out there. I must resort to many painkillers every day just to get some housework done and be a mom. I just started this Savella. We will see…I really hope if brings me some relief as my daily existence is miserable to say the least. The quality of my life has degraded considerably. I just turned 40 this year and I feel 90! I can totally sympathize with all you sufferers.

I was diagnosed with Dystonia and FMS among other things. The Dystonia causes my muscles to “guard” and basically turns them to stone balls. I now get 400 units of BOTOX injected via 50 needle pricks, every 3 mos FOR THE REST OF MY LIFE as there is no cure for the Dystonia. I take 400mg of Lyrica, Vicodin and now Savella.

I really hope that this drug can give me my life back. I am too young for this crap!

Good luck all….

April 2, 2010 at 6:46 am
(130) Amie says:

Hello Everybody! More fantastic days for me! Savella is continuing to work. I have not missed a fibro related day from work since I started this med about three weeks or so ago. I am not so stiff and the pain is 200% better, even though my lower back and buttocks still hurt a lot. Fibro fog is almost nonexistent. The pain that was in my arms and legs at night is almost gone too. I sleep much much better. I feel like myself again!
Victoria, I know what you mean by the different sensations. I call all of it pain, but at different times the pain feels like tingling, burning, stabbing, cramping, stinging– you name it. I am so sensative until when someone wants to give me a hug, I recoil and tell them to go easy. The pain in the tender points is piercing. And I know what you mean about wondering whether something besides fibromyalgia is a problem with you. Before I started Savella, I had gone through their process and made an appoinment at Johns Hopkins Hospital for a second opinion on my diagnosis and treatment plan. After getting up by 2:00 a.m. to get to the appointment by 9:20 a.m., I saw a rheumy who asked, “Did anyone tell you that we do not treat fibromyalgia here?” I was absolutely floored. I wondered out loud why had I been given the appointment to travel so far for that kind of reception. She said that she wanted to rule out other rhuematic deseases, but just asked me the usual questions about my life and my family. No tests. But she did order blood work to check for Vitamin D. I came home to do this so I will see my primary doctor today to discuss results. The rheumy also suggested aquatic therapy and charopractor visits. She said exercise and strength training would be helpful. And weight loss will take the pressure off my back. After Savella, I feel able to do this, but before, I couldn’t even think about it. I hope this helps. God Bless You All.

April 2, 2010 at 8:55 pm
(131) Abby Hamilton says:

Thank you everyone for your fibromyalgia histories and your experiences with medications. I have not been in touch with anyone else who has fibro, and I feel so much saner, having read the comments. For years now, in spite of having been diagnosed with fibro by four doctors, I have been unsure if I really have an illness or if I’m somehow imagining all this. So I go around apologizing all the time for being slow, tired, confused, unfocused. I don’t even tell people about the pain because I don’t want to be thought of as “whiney’.
What has helped me with symptoms: outdoor exercise, my 12-step group, meditation, friends,pets, and laughter. Medications, so far, have not helped, though I’m just starting Savella.
I wish you all good fortune in finding effective treatment. You are brave people.

April 2, 2010 at 10:16 pm
(132) Cathie says:

Thanks for your stories. I’ve had fibro about 25 years; was finally diagnosed in 1993. I’ve tried many things and here are my experiences. Cymbalta – side effects were intolerable. Started taking Savella last June (2009). Have had immense pain relief, my fibro fog is nonexistent, sleep has improved, energy has returned, fatigue is almost gone except if I overdo. The main side effect – constipation, which has been a totally new experience for me since I was diagnosed about 10 years ago with IBS. I do exercise in a warm pool 4 days or more per week and it keeps me mobile and my muscles stretched. So far, I’m really satisfied with Savella so hopefully that may be encouraging to some of you. Keep positive.

April 3, 2010 at 8:06 am
(133) michell says:

I have just been put on Savella by my doctor. I had been taking Lyrica for over 1 1/2 years. While this did relieve some of my pain…it kept me at about a 5 on a scale of 1 to 10..with 10 the highest for pain. I still would reach an 8 to 9 on Lyrica. I am just starting on Savella..3rd day on it. I am having nauesa and dizziness with this but hope that it will subside. I will take the nauesa and dizziness over the pain. I sure hope this stuff works! Best to all

April 7, 2010 at 6:41 pm
(134) Kathi says:

Glenda, post #89, I live in Fort Worth and would love it if you would give me the name of the D.O. you see. Would that be possible? Also, just got the new titration pack of Savella but am too scared to start it…

Thanks!!

April 8, 2010 at 12:06 pm
(135) sheila says:

i started taking savella two weeks ago, so far so good i’m just afraid to get my hopes up. after ten years of suffering i finally found a doctor who would listen and believe me about the pain i was in. life has been a struggle and no one seems to understand just how bad the pain is. i also take an antidepressant but they didnt take me off of it they just added the savella. the great thing is my antidepressant wasnt working as well as it used to with the savella not only has it helped the pain it has also made me feel better emotionally.

April 13, 2010 at 8:01 pm
(136) Emma in Louisiana says:

I was put on Savella a month ago. I was just told a month ago I have fibro by my nuero surgeon whom told me I have been sent in the wrong direction for 6 years. The pain betwenn my shoulder’s were so bad I couldn’t even peel a potato I would have to wait for my husband to get home from work to rub me down with activeon which did ease the pain as long as I did nothing. It was so depressing I was at my wits end with it. I told my primary doc 3 months ago the pain was chronic but he told me it wasn’t and gave me nothing. So when I was told I had Firbro I printed out the page took it to him I pointed to where it is said can cause chronic pain he said I know what Firbro is I said do you see where it say’s “Chronic Pain ” so he put me on the pack of Savella it did help and I told my husband it’s so good that he doesn’t have to come home and rub me down just o cook his meal. Now that I am on the script. of 50mg in the am and 50 at pm I have had side affects as of this morning 4-13-10 I went to get up out of bed my head was spinning my eye’s were blurry and I developed diareha. But I can deal with this I guess, anything is worth dealing with other than the pain between my shoulder blade’s. I did try Cymbalta and lyrica but wasn’t given to me for Fibro. I couldn’t take either both made me have breathing problem’s so I hope the Savella I can tolerate. I have been to nureologist, orthopedic, chiropractor,s pain management and no one seemed to know my what the problem was til I went back to the orthopedic doc and he sent me to the nureo surgeon and he is the one who told me I had Fibro. My heart goes out to all of you that has this I know the pain and it is very painful. May this med work for us all because if it doesn’t I don’t know what else we can do. Every med has a side affect I’m also on Flexeril and loritab but he told me not to take the flexeril unless I really need it because it can damage my liver. So far Savella has stopped the pain it’s the side affect’s I’m dealing with now. I hope and pray they go away. I like to have fell off my back porch because of the dizziness. Please let me know how you all are doing with your side affects. Thanks and God Bless Us All Emma

April 14, 2010 at 12:51 am
(137) pam says:

this is my second time trying the savella. the first time i tried it was in october 2009. by the time i got to 25mg 2x day, i was dry heaving all day. this time my doctor prescribed phenegran to take one hour before the savella. so far so good. i hope this med helps. i was diagnosed with fibro in 2005. i am doing much better now but i take a handful of pills daily. i am an RN who is no longer able to work. the thing i hate the most about fibro is that it robs you of your passion

April 14, 2010 at 3:09 pm
(138) Valerie says:

I took myself off of Cymbalta(not working anymore) my internal medicine physician suggested that I try Aleve. I am pround to say that it has been working for me(4 a day). I drink a cold Bud Light Beer at night to put me to sleep. I am trying to get away from all of the different medication that do more bad than good in the long run.
Try things that help YOU feel better.

April 14, 2010 at 10:24 pm
(139) Shannon says:

Wow, I am really glad to see that I am not alone with this pain, fog, and lethargy. It has been an awful 3 years, seeing 17 doctors, and being told that there isn;t anything wrong with me, or that I may have rheumatoid arthritis, that I don’t have RA, and that I may be disposed to get RA in the future…I was very sick with a parasite infection (from living in Africa) and the general consensus is that’s what changed my entire immune system. I finally found an amazing doctor who listened to me and reviewed my history and the tons of blood tests. I’m taking 1200mg of gabapentin at night and 300-600 during the day. The tight joint pain is finally gone from my feet and hips and mostly from my hands (I type for work, so some pain is inevitable). I am finally able to sleep – the anxiousness that I was experiencing after 3 years of bad sleep was terrible – ruined work and friendships. I am finally beginning to feel better. Today is the first day I’m taking Savella, I know my body really well and am on the look out for side effects. But the side effects I felt with the gabapentin left after a couple weeks. Lyrica made me really anxious, so that was out!

I read a lot of your stories and I’m glad that I am not alone! I also know that I am beginning to feel better, and that many of you can feel better too. In addition to my pharmaceutical meds, Gabapentin and now Savella (we’ll see if it works) I take probiotics at night, magnesium, and calms forte to sleep and vitamin D, vitamin B, fish oil and tri-boron. I notice that my pain really gets worse when I take out the natural supplements – talk to your doctor and make sure you have a doctor who is willing to get creative and who listens to you!!!

A good doctor who is willing to help you is your best asset – I know they’re hard to find, but make sure to advocate for yourself and for your health. I wish all of you the best. Thank you for sharing your stories.

April 15, 2010 at 11:25 am
(140) JT says:

My rheumy just sugg’d Savella; frankly, I don’t want to go on it; I have insurance and it will cost me $60/mo. As I waited for the doctor to come in, I could here the pharmaceutical sales reps schmoozing with the staff and was reminded about the shady relationship w/ the pharm co’s have w/ doctors. We are all basically guinea pigs. There is a special running on MSNBC called American Greed and they had a segment on Pfizer and the Bextra calamity.

April 15, 2010 at 6:04 pm
(141) sharon says:

I am on both SAVELLA AND CYMBALTA It is working fine. My pain is so hard that I would have done anything for relief. I have just been told that I had Fibromyalgia. SO I am leaning as I go also.

April 17, 2010 at 12:56 pm
(142) MIM says:

I had fibro diagnosed for 19 years now, though I am pretty certain I have had it all my life. I have asthma, diabetesand Prinz-Metals (sp?) angina. I have been on Pamelor for 19 years, and it has been my steady med all along. I have participated in several fibro studies and anytime I stopped the Pamelor, I was almost crippled. I have tried everything under the sun. The phenteramine was the most helpful, I had no symptoms, but I had taken it as a phen/phen combination, and when that went off the market, my pain returned.
I have been on neurontin, Lyrica, Cymbalta, Ultracet, several muscle spasm relievers, and God knows what else. I too, feel like a guinea pig for medications. My B12 level and vit D levels are fine.

I started a trial pack of Savella and the side effects have been really rough. I am nauseated, have migraine grade headaches, my fibrofog has increased to the point to where I can’t drive most days. I also sleep like the dead, for about 4-5 hours each afternoon and at night I toss and turn all night. Both at nap time and at night I have very lucid dreams and a lot of nightmares. I have lost about 3 lbs in the 12 days I have been on the Savella. I have started weaning myself off of it, and the side effects continue. The constipation is so severe I take 3 colace and I have to take cascara daily just to have a BM. It is also driving my IBS crazy. The distention I get daily is very painful. So another medication off the list for me. I was reading this blog for the first time to see if side efects went away, but I see that there are several other folks like me that are feeling the same.

Depression has never been an issue for me, but on the Savella, I can tell you, if anyone around me had a problem, needed help, needed dinner, I just didn’t care. I stopped answering the phone, readin e-mails, even communicating with my husband. So for this reason too, I would rather have the pain than the poor quality of life.

I’m glad it’s helping some of you. I guess some of us tougher birds just have to rely on the moderation of activity, diet, mild exercise, meditation and other palliatives to get through the day.

April 22, 2010 at 2:33 am
(143) Mandy says:

Savella may not work for eveyone. But what does?? Savella takes 8 weeks to become theraputic. But if you have the mind set that nothing will work then nothing will. I have had fibro symptoms as long as i can remember and my mom remembers further back that even as a child she knew. This has been the worst year of my life because of my pain and fatigue. Some times i cant sleep because the pain is so severe and i will wake my husband sobbing. BUT.. the savella is starting to work. My overall pain has lessened, now i realize how weak my body has become. I am still suffering from fatigue, but dont sleep as much. Every thing takes time. So give it time before you just give up, Savella works!

April 22, 2010 at 10:41 am
(144) Kati says:

I have been suffering for about 10 years, was a very active person, always going to the gym, running, than bought a home that needed to be gutted, did manual labor, gardening..you name it ..i was extremely active…after all those things in my early 30′s things got very bad, pain..so intense no idea ..they said herniated discs et…tried everything…Accupunture, Herbs, Chiropracter for the NY Jets, Various Meds, anti depressants, facet blocks, epirdurals and pain meds, the last very much against my wishes..i wanted a solution not a mask and not someone comfortable with narcotics afraid of addiction, out of work on disablity several times over the years…no life…none..just work and rest so i can make it to work…WELL Here is the Solution..i was put on Savella 3 weeks ago…appx..begginer pack for 2 weeks than 50 mg 2x a day..LIFE CHANGING….a tiny side effect has just been waking up a little to early..but after all I have gone through..i will deal with that….I say try it..if you have gone through what i have …..give it a shot. I never thought i would feel better again….i’m so grateful for Savella……

April 23, 2010 at 1:15 pm
(145) amanda says:

my first day on this dont know about it though savella anybody

April 23, 2010 at 5:35 pm
(146) mija says:

Hi everyone

I was diagnosed with RA….hmmm…6 or 7 yrs ago..I’m 44….and worked 40 to 50 hr work weeks until about a year ago…when from the stress of work…and other things caused my body to begin to shut down….I use to be obese….before all of this…and when I stopped my job finally…I had dropped to 180 pds..in less than a year….loved that part…*smiles*…I use to be over 300 pds….
Well I relocated….new dr’s ..etc…and was diagnosed with severe depression and anxiety…what I found out in my case….was that all these things fell under the “umbrella” of RA…and fybro….(which i did not receive that diagnoses until I relocated…but thinking back..I have had it atleast as long as the RA….I was on pain meds (still am for break thru pain)…although outside of a pain clinic…it was almost impossible to get a rx for those when I relocated…I am now on lyrica 2x day cymbalta …which has been cut back to once a day now that I am on the savella…..I also take prozac…at it’s highest dosage…but I wanted to say…since starting the savella…I feel….normal….for the first time in years….and if this continues hopefully the dosage of prozac will lessen if not discontinued all together…
More than anything I wanted to encourage others…to not give up…there’s hope…it might not be savella that produces the result you long for…but for me….if it helps with just one of my many problems…I’m grateful….

April 26, 2010 at 5:21 pm
(147) Mickey says:

I was diagnosed with Fibromyalgia in 2005 after running the gamut of Lyme Disease and Lupus. During that itme I was prescribed 1800 mg of Neurontin per day. I too was a drooling zombie which led to a near nervous breakdown. I went through Neurontin withdrawal and onto Zoloft. The Dr. wanted me to try Lyrica, “a close cousin” of Neurontin but at that point I left for another Dr. She recommended vitamins, sleep, and a healthy diet. My nutirtionist also recommended fish oil. Since then, my pain is manageable and judging from the comments here, I won’t be trying Savella. I found the “fibro fog” was from the medications. Today I am taking D, B complex for stress, multi vitamin, and 4 fish oil capsules per day – the odorless kind. The fish oil was like a mini-miracle for me. We also invsted in a memory foam mattress, also a mini-miracle. I have also lost over 80 pounds, but that doesn’t seem to have made a difference. I believe in the vitamins, fish oil and the new mattress – i just can’t function on those drugs. Good luck everyone!

April 26, 2010 at 10:03 pm
(148) katherine says:

I have had fibro for 20 years and have been on neurontin, lyrica, welbutrin and others. Went on Savella three weeks ago. It was the best med I have ever had – pain went to almost normal, I could remember short-term and long-term, knew what day it was and what I was doing that day! Between 25X2 and 50×2 I started to have very high blood pressure with serious eye problems – fuzziness as well as visual field shutting down. Difficulty reading and couldn’t drive. Specialist said blood pressure went so high it caused eye arteries to tighten and even hemorrage . If this happens to you, he said put two soup spoons in the fridge and press coolness to both eyes until you see the doc. Conclusion: I liked the med but it’s too dangerous for me. I have never had blood pressure problems in the past.

April 28, 2010 at 3:06 pm
(149) John says:

Savella was just prescribed for my wife, and the doctor gave her samples.

April 29, 2010 at 12:26 pm
(150) Crystal says:

i just started this medicaiton yesterday and was given a 14 day sample pack from my physician and a script…..hoping it works wonders….I sure could use a break!!!!

April 30, 2010 at 12:27 pm
(151) Tammy says:

Can u take it with Lyrica?

May 1, 2010 at 11:11 pm
(152) Cheryl says:

I’ve been on Savella for about two months now. I have seen a difference in how I feel. Most days I have more energy and I’m able to do things I could do before taking Savella. I am having some problems with side effects such as nausea, hot flashes, vision problems, constipation and some weight gain. The nausea is much better as long as I take my meds with food. I am hoping to be able to stay on this as I do see a difference in how I feel overall. I gained 20 pounds when I was on Lyric and had to go off it. As long as I can keep the weight gain under control I will try to stay on this as I do feel it is helping. Watching the side effects closely as I don’t want to cause any other health problems.

May 3, 2010 at 12:01 pm
(153) Donna says:

I tried it as directed and now am at 50 mg OD
however I can’t function the next day~ all I
want to do is stay in bed and sleep.
Anyone else having this problem?

May 4, 2010 at 7:17 pm
(154) Mona says:

I have been on Savella for three months. It worked instantly for me, and actually only headaches for first few weeks. I noticed when I forget to take the medicine; I feel dizzy and have more side effects. Overall, I think it has helped me become physical, I was on depression meds and i felt like a zombie, but Savella has not screwed around with my mental state so I like it. It seems like it is different for everyone, but I think if you have fibro, that it is worth trying because it help bring me back my life. I have actually felt happy, like I have not felt in over 5 or 6 years.

May 5, 2010 at 1:26 pm
(155) Amie says:

Hi Everybody! Savella worked instantly for me back in March, and is still working now! I have a lot less nighttime pain in all my limbs, headaches, and morning stiffness than I did before Savella. My general health feels so much better. The difference is absolutely amazing! I coped with unbearable tiredness, sleeplessness and fatigue before Savella, but those symptoms are somewhat bearable now. Wooziness is problematic. And I had to get another blood pressure pill added to the ones I am already taking. Sometimes I get nauseated too. Yet, overall, this is the best med I ever had. I would rather cope with the blood pressure problem, the reduced amount of wooziness, tiredness, sleeplessness, and nausea, than to feel the way I did when Savella was not a part of my treatment plan. In addition to savella, I take ultrim, vitamin D, vitamin B-complex, fish oil and, a multi-vitamin. I also walk, garden a lot, and use a push lawn mower.

May 12, 2010 at 6:51 pm
(156) Anna says:

I’ve been on Savella for two weeks now. I’ve noticed I’m sleeping through the night and feel physically great. I’m not all sore and stiff when I wake up. I’ve been a bit depressed, but I think it’s because of issues in my life not the medication. I haven’t had any stomach issues at all. I think it’s working really well.

May 16, 2010 at 2:19 am
(157) Sally says:

After reading all of these postings, I am quite depressed. I am on my 3rd week of Savella, & I haven’t gotten any relief at all. I’m a little concerned too because my doc did not have me stop my anti-depressant, Celexa. Now I’m even more tired, & getting more headaches than usual!!
I am really happy for those of you getting some relief … I guess I’m just jealous!

May 17, 2010 at 3:48 pm
(158) Bradybunch says:

I was on Cymbalta since Jan until last week (May9th). I gained 30lbs on that and was soooo tired all the time. I was given Savella at my neurologist today. Can anyone tell me about weight gain specifically with this drug?

I am on several other meds also, but for sure the Cymbalta was really messing with me. Since being off of it I am an emotional wreck. I sure hope this helps and not hurts me more…..

May 18, 2010 at 12:27 pm
(159) ermelinda says:

Have been on Savella for 1.5 months. No weight gain like Lyrica. Nightmares, sweating and HOT, severe nausea all the time, and expensive. Headaches at first but that minimized at lower doses. Did help my pain about 25%.

May 20, 2010 at 9:51 am
(160) Laura says:

I do not have Fibromyalgia – I have degenerative disc disorder in my lower back (L1, L2) and a stenosis. My back started flaring up about 6-7 years ago. About 3 years ago the pain was constant and increased consistently since that time. About 2 years ago it became all-encompassing. I am a photographer and had to close my business because I was unable to work/stand/sit for any length of time. I began taking vicodin 2-3x’s a day (or more). I have a 3 year old son and I cannot tell you how much of his life I have not been able to participate in because of the pain. I was a happy, upbeat, normal person but the pain changed me entirely – I have never been suicidal but I can relate to people who are because it got to the point that I would say “I cannot take it anymore, it just is too much”. I lived everyday, every minute of my life with pain shooting down my legs. Stiffness was so bad I could barely move. I tried EVERYTHING (injections, epidural, therapy, chiro, every drug on the planet, etc) short of surgery, which I was told may or may not be effective. I had appointments lined up with surgeons when my doctor gave me Savella).

I have been on Savella for two weeks and it has TOTALLY CHANGED MY LIFE. Pain in reduced by 90%. Stiffness and immobility is dramatically reduced. Whatever residual pain I have, is treatable with some Advil (never the case previously). My personality is back, my energy level is waaaaaaaaay up. I get a little stomach ache occasionally when I take it – that’s about the only side effect so far. Oh and the weird dreams, as I see is pretty common. All things I can live with!

Without being overly optimistic…if there are not side effects moving forward….I believe I found an answer. It literally was a miracle for me. It gave me my life back. Every morning I wake up and get out of bed pain-free….which I haven’t done in years. I cannot believe the change.

Is it possible that this drug is more effective for people like me, with back problems, and not as effective for people with Fibromyalgia?

I will pray for all of you – I can ‘feel your pain’ – and I hope that if this drug isn’t the solution for you, that something else will be!!!! :)

May 21, 2010 at 10:44 am
(161) Mom23b's says:

I’m on day 7 of the 2 week Savella Titration pack. I really think I’ve been suffering with Fibro for YEARS, but only just now found a Dr that will listen and seems to care that I really do feel actual pain!!!

I’ve been to Cardiologist, Neurologists, Back Specialist, and any other sort of ‘ist’ you can think of… basically they told me to lose 40 pounds and exercise! UGH!! I would if I had enough energy to function. Not to mention the brain fog has been horrible.

Today was the first day of the full 50mg dose and I did feel nausea, but once I ate something the nausea has eased…I also notice more energy during the day and am extremely encouraged that I am not so stiff in the morning. Also, the brain fog is lifting!!

Before starting Savella, I needed about 30 minutes each morning just to get myself motivated and loosen up from the night. It’s much easier to get my day started now, since taking Savella.

I also suffer from depression and anxiety, which I’ve been prescribed Pristiq and Xanax. So I’m taking Pristiq and Savella together and the occassional xanax as needed.

I’m hoping that the Savella can give me back my life – I’m only 40 and I feel like I’m 80… I never have any energy to do anything with my children. Just a trip to the grocery store puts me back in the bed for the remainder of the day – this is no way to live!

I wish you all much luck with this drug!

I know this disease has many symptoms and it’s hard to make others believe just how miserable we feel!

I’m praying that Savella is the answer!

May 21, 2010 at 12:19 pm
(162) Sherrie says:

I have been taking Savella now for aprox. 5 weeks, I noticed a HUGE difference from the very first day.
I have had injections and been on pain meds. since 2001. When my Dr gave me samples of this MIRACLE drug my pain level was 8-9, now it is around 4-5.
Thank GOD we have a medication that works! I am so sorry that it doesn’t help everyone , sure hope that all of you that Savella doesn’t help finds something that will!! I feel like a million bucks MOST days. God bless you all

May 26, 2010 at 3:25 pm
(163) Charles Goff says:

I’ve been on the Sevella now for a month. I think that it’s doing some good. I say think because at the same time that I started the Sevella I had also increased my Oxycontin to 40mg 3X a day. It may be the Oxycontin, the Sevella, or a combination of the two. The only side-effect I’ve had is some pretty nasty constipation. In a few months when the increased Oxycontin levels out we’ll see if the Sevella is doing anything on it’s own. I’ve noticed that I don’t watch the clock waiting for my next dose of Oxycontin. That’s an improvment in itself!

May 27, 2010 at 11:21 am
(164) Lorraine says:

Soft, gentle air hugs to my fellow fibromites. :)

Erika (#126), those shocks you describe often happen with Cymbalta. If you google “brain zaps” you’ll get some info on that.

My doc gave me 2 two-week Savella trial packs yesterday. She says she prefers to start off very slowly on this med, so I took one pill last night, and will take one pill tonight. Tomorrow, I’ll take a pill in the a.m. and then again in the p.m. Essentially, it will take me twice as long to get up to the higher dose, but she feels that will alleviate any possible negative reactions.

When the nurse brought me the meds, she shared that they’ve had a very high rate of success with titrating this way.

We’ll see. I am optimistic. I’ve used Cymbalta for my fibro in the past. It worked initially, but after a while, not so much. Then, I didn’t have med insurance, so I was on the only meds I could afford: Vicodin as needed for pain (2 or 3 times a day), flexerial and klonopin to help me sleep.

I tried gabapentin, but even at a very low dose, I felt so weird. Ugh.

If you’re looking for a really good supportive website, google National Fibromyalgia Association (they’re listed on the back of the Savella product insert). There are also good (and not so good) chronic pain support groups online.

One of the best things I have done for myself is to join a local fibro support group. We help each other with good ideas, understanding, and have speakers come in, etc.

May 28, 2010 at 7:26 pm
(165) Marc says:

i have really bad IBS, will Savella help or make it worse for me. Sometimes it can be so debilitating the IBS.

May 31, 2010 at 12:18 pm
(166) Linda says:

Started Savella yesterday. Feeling like there is hope. I am awake!

May 31, 2010 at 9:06 pm
(167) TracyB says:

What a miralce drug… i’ve been on anti-depressants for 10 years, doctors trating me for depression, which all I have is Fibro and extreme anxiety.

June 1, 2010 at 2:06 pm
(168) Ellen Lewis says:

I have been on Savella 100mil twice a day and am doing very well. I take very few pain pills. I use to take a lot a pain meds but now I hope to get off the pain meds for good. My only complaint is about the price I have to pay 80.00 and insurance pay the rest for now until go into the gap, then what? I have been on full dose since 5-03-2010. May
God bless all that has Fibro. I have never known pain like this and it is very depressing, but there is hope with Savella.

June 8, 2010 at 9:09 pm
(169) Sandy says:

Is anyone taking Savella for depression and not fibro? Either way….is anyone having headaches. I have forgotten to take my pill a time or two but can’t keep track if that is when I am getting heachaches or not. Seems like I always forget my pills on Sundays and then Monday morning I have terrible heachaches. Maybe I just need to pay more attention. Just for reference, I have been on Savella for about three months now. I do not have fibro but have severe arthritis in my knees and am too young for knee replacement. I also was suffering from anxiety and bouts of depression so my doctor suggested Savella to help with both. After three days I noticed a positive change in my mood and after about a week noticed a big difference, especially at night, with the pain in my knees. The headaches are the only side effect and I am beginning to think it is my fault for skipping doses. I have also had absolutely no weight gain.

June 9, 2010 at 1:27 am
(170) will scott, jr. says:

Started taking Savella about 3 months ago. I have severe back pain due to 5 failed back surgeries along w/2 spinal fusions of the L2-S1, 5 knee surgeries, a stroke right after Christmas 09 and a bout of Lymphedema 2 weeks later.
I cannot say with being truthful that Savella is the all great pain reliver that some claim it to be. I am still taking 150mg of lyrica, along with several other meds for muscle cramps and to sleep at night. I am taking the maximum dosage allowed of Savella and have noticed some slight relief from pain, but nothing to write home to the folks about. And there is nothing that I have been given for the sometimes short pain burst that come from even everyday things.
I have noticed a great weight loss, lack of appetite, and the “sweating” on a somewhat constant basis. Also have terrible “Hot Flashes” at anytime of the days and during the night.
If there are some of you out there that are looking for something that will take away all your pain. It has not been invented. Fental patches, valium, savella, lyrica, rozerum and another medecine are nothing compaired to the pain that I go through daily.
So days I cannot get out of bed, then it takes about 5 minutes before I can walk. I have noticed a change in my eye sight. I have lost the edge I had in my attitude and my anger is much better. But I am considering going back to the old ocxicontin and the other more nartotic pain meds. I can take almost anything without side effects, but I refuse to continue to be in this pain I am in “ALWAYS”.
Savella, is not the great pain reliver the docs make it seem to be. Let them know this if you are still suffering.
Hope the Force is with YOU.

June 9, 2010 at 11:15 pm
(171) Net says:

I had a terrible allergic reaction to lyrica. They told me the only thing that did not happen is my throat did not swell shut. Thank god. Well hoping savella would work but I have had the worst side effects. I got so sad, had no want to eat, got sick daily, more pain, headache and many others. My dr told me last time I saw him that he is not even sure I even have fibromyalgia anymore. But we had to try every med for it just to be sure we tried all we could. I pray that this med helps others. But just make sure you keep notes on how a new med makes you feel it makes things alot easier.

June 11, 2010 at 4:43 pm
(172) Betsy says:

Scroll up to #14 and read his comments again! I’ve had fibromyalgia for many years and without medical insurance. What I found that has very successfully worked for my fibro pain as well as my general health is MAGNESIUM! Because Americans are suffering from a severe lack of magnesium, we suffer from many health problems, not knowing the cause is lack of magnesium. I use Ancient Minerals spray (transdermal) magnesium because it is immediately absorbed into my body and acts immediately on fibro pain. Gone!! I did a lot of research before I bought it and read a lot of blogs as well. Please do the same! This stuff works immediately when sprayed on your body. I also take baths in Epsom Salts which are magnesium as well! Big help! Good luck to you all!

June 12, 2010 at 5:00 pm
(173) Christa says:

Hi, I’ve been on Savella for 3 weeks. At first, my joint pain was nuts… Then, much much better. I know it’s helped pain a lot, and I’m thrilled. The problems is, the sweating is crazy. If I work at all, or do anything, my hair is as wet as if I just got out of the shower. I sleep with a towel at night and wake up sweating. For that reason, I am weaning myself off it. Talked to my pharmacist and I’m cutting 2/3 of a pill for a few days, then 1/2 then 1/4. I know there can be withdrawals so if I feel something, I’ll just go up a bit and move down more slowly. I also had a rough patch on my neck for a couple of weeks. No biggie but I wish I could keep taking it, it really helped pain and energy.

June 16, 2010 at 4:46 pm
(174) Kathie says:

I started the 4 week starter pack 3 weeks ago. The first two nights I slept like I haven’t in ages. After about 4 days, I was so nausous I was ready to quit. My Dr. prescribed meds for that and I’m fine. Just about out of the anti-nausea meds, and ready to try just the Savella. So far I like it.

June 20, 2010 at 2:11 pm
(175) Renee says:

New to this site. Am technically on week 3 of Titration pack…but sloowly climbing from the 25mg 2x day to 50mg..The first day I tried to go up to 50, Immediately got sick. Here’s my pro/con list as of now, vs Cymbalta: (I have Lupus (SLE) , Fibro and arthritis)

PROS-
OMG..I’m awake again! Almost immediately, got up, ready to go. No more nearly falling asleep at work, car naps..coming home , back in jammies.
Virtiually no pain, seemingly less “swollen” and achy
- Weight LOSS? Woo hoo! put on over 20lbs w/Cymbalta and prob combo of inactivity

Cons- Only w/in the first 2 wks
-Did experience bad nausea..and unable to sleep for the first week..BUT later read that you should really try the 2nd dose no later than 2p-3p..or be ready for that. Pushing back my time of 2nd dose really helped with the sleep.
- Week 3..Seem to be more “on edge” As happy as I am with my new found energy. It’s as if I have NO patience..am ready to snap on a dime. Anyone else?? Hoping this is temporary too. Have lost over 6lbs in under 3 wks..have a clearer head..and hoping this works good for others.

June 29, 2010 at 11:32 pm
(176) fallenangel says:

Savella has been available for quite some time…I’ve been taking it for the last 7-8months. I also take Lyrica, Norflex, Norco&MScontin. When I 1st began the Savella I noticed that it basically just increased that “Lyrica, fuzzy buzzy wierd braindead feeling and my memory is definatly not what it use to be…also, I have Bipolar 1 Disorder and it quickly threw me in2 a manic episode and my Lithium had 2 be increased by 75%.

July 7, 2010 at 11:19 am
(177) Sugari says:

I am a 52 yr old woman that was diagnosed with RA over 15yrs ago, Osteo Arthritis caused knee replacement in my right knee, more Arthritis in my left knee, lower back, both hands, both shoulders, neck, and a Fibro/CFS diagnoses over 5yrs ago. Am currently on Lyrica, Cymbalta, Buspar, and Xanax for depression and anxiety. Along with the meds mentioned, I was on Pain med Norco 10/325 for over 6years. It stopped working, Dr’s said I was addicted (yah think?) and my Neuro/Pain Mgt Dr. changed me from Norco to Nucynta. The 75mg Nucynta 4 per day helped as well as Norco did as first. I was actually able to do some yard work off and on. Now I am on the Savella 2 wk Titration pack and yesterday started 50mg twice a day. My Dr. (at the same time) is trying to wean me from the Nucynta. now Im at Nucynta 50mg, 3 times a day.
My problem is…Savella does not seem to be working for me at all and I cant handle the pain being the pain meds have been decreased. I want to give Savella a chance because you all seem to have found the relief you’ve been looking for. Why isn’t it working for me? Should I still give it more time or if its going to work, it should have started helping by now? Was my Dr. too quick in lessening my pain meds? The only side effect I seem to have is bad anxiety attacks and the depression always comes with the pain, but I’ve had these before, but not anxiety like this. Any advice would be greatly appreciated.
Thanks for taking the time to read my tale of woe.

July 10, 2010 at 11:40 am
(178) Rita says:

Just started on Savella and already noticing positive results! I have tried numerous meds and treatments for Fibro with out long lasting relief. Lyrica worked at first but as it became ineffective and Dr had to step up dose, my small frame put on so much weight I was miserable. Stopped that and started Cymbalta. It helped for a few years when taken along with muscle relaxants and pain med, but all stopped working after a couple of years. Was weaned of Cymbalta and started Savella along with Topomax (Migraine preventative) as my migraines were out of control. After one week have noticed amazing improvement in headache and pain and have not needed Migraine pain med or muscle relaxers or other pain meds which is rare for me and very welcome. Feeling more energetic and practically pain free after many years of misery. tummy is a little upset, but pharmacy says that should get better with time and when taken with meals. Feeling a little “medicine head” and disconnected, but pharmacist says that is normal at first and should improve and some of that may be body adjusting to coming off Cymbalta after so long. I’m hoping for the best. Savella may be an answer to prayers for so many of us who have suffered so greatly for so long….

July 15, 2010 at 1:48 pm
(179) CK says:

I don’t understand why people KEEP TAKING XANAX when they are having increased anxiety on it. Taking more will not decrease your anxiety levels, only make them worse in the long run. It has a rebound affect, the more the take, the more you need to take! Plus, everyone I know that is on it, takes it before any other drug, which makes me think its more addicting than most. AND they forget everything. I hate having conversations with people taking it because its like talking to a brick wall most of the time. I know it does work for short term but long term everyone I know gets increased anxiety. But they keep taking it and taking it! Drives me crazy! Anyway, I’m starting Savella and scared b/c Cymbalta had such weird side effects for me, I felt like cutting myself and majorly weird thoughts and feelings. I just pray it works, I’m at the end of my rope. Tried everything under the sun, had Fibro for 20 years, it wasn’t until recently that they added nerve pain and joint pain onto the long list of symptoms. I guess its just like any other drug, works for some and sucks for others!

July 25, 2010 at 1:30 am
(180) Rachel says:

I took Savella for 3 days and had to stop taking it immediately. I got ridicuosly shaky while taking it. My pharmacist recommended that I stop taking it and go to the ER. There I was told I was having Serotonin Syndrome. I was on 2 other meds that worked with the chemicals in my brain and then the Savella was just too much. So, I suggest if u want to try this drug, make sure that your doctor knows what other meds u r own and pays attention to them.

July 26, 2010 at 7:17 am
(181) Cyndi Lewis says:

The medication IS an anti-depressant, no matter HOW they market it. Ask your pharmacist!! I have been on it for 2 weeks with absolutely NO RELIEF….and NO SLEEP. No better than Cymbalta. It also hurts your stomach and causes nausea and night sweats. All in all…..useless and a waste of time and money!

July 26, 2010 at 8:24 am
(182) JC says:

I haven’t gotten more than 3 days and I feel so bad with a headache and indigestion, I’m quitting.

July 29, 2010 at 9:04 am
(183) Mary says:

I am on my second pill and I am not liking this. It is making me light headed. Last night it made me horribly nauseous and caused my migraines to come back, which is even better since I can’t take my migraines with this. I dunno if I can do this for 3 weeks like my doctor wants me too. I would rather have body aches than light headed, nauseous and have migraines.

July 29, 2010 at 10:50 am
(184) Matt says:

It seems like it really works for some, and doesn’t for others. I’m taking so many medications and supplements for fibro and chronic fatigue I literally couldn’t list them. Tramadol 400 mg per day worked a while but I got used to it. Added Vicodin, up to 4 times per day, now tolerant to that.

I’m trying to reduce the dose and number of meds that influence serotonin (and meds in general) to give the Savella a chance. On day 5, already 25 mg twice a day since I stopped Effexor on day 3 (after cutting the dose in half on days 1-2).

So far I’ve got the dizziness and some nightmares – the kind where I think I’m awake but I can’t move, breathe, or scream.. Like others who have written, I can’t say how much is withdrawal syndrome from stopping Effexor and how much is Savella. But these symptoms are pretty normal when you start antidepressants. If you can stand it, it can be well worth giving it at least 2 weeks once you’re on the full dose.

Obviously if your doctor or pharmacist (or you) thinks you’re getting serotonin, it doesn’t hurt to cut back for a couple days. Of course, it’s more difficult if you’re also trying to avoid the excruciating withdrawal (for some, including myself) from Effexor and Cymbalta.

400 mg of Neurontin helps me sleep at night. Lyrica at various dosages seems to help *a little* but also may have contributed to my +36% weight gain(!) over the past couple years.

I’ll try to post more later. The posts from people who have been on the drug for a long time are the most helpful to me.

July 30, 2010 at 12:36 am
(185) Justin Palmer says:

For anyone having trouble paying for Savella, check out this savella coupon. It says it gets you 19% off. This is for cash paying patients only though.

August 1, 2010 at 6:17 pm
(186) Kathy says:

I have been on savella for about four months. My second time around. Did’t work for me the first time. Then my Dr. put me on lyrica. That did not work either. So he put me back on savella. I take it but I really don’t feel any different. Still have pain, stiffness and foggy head. I just can’t seem to come to terms with the fact that I have to live like this forever. I can’t do so many things I used to. People just don’t understand that I look ok on the outside but they have no idea how I feel on the inside. Can’t seem to make them understand. Tire of feeling like this. Only thing that makes me feel better and relieve the pain is percocet. Don’t want to be on that forever.

August 2, 2010 at 11:35 am
(187) MissyM says:

I am a Fibromyalgia SUFFERER and was put on Savella trial pack 2 weeks ago. I have to say this medication is one of the BEST, I’ve ever ever been on. I have tons of energy and mental clairity without being cranky, emotional, jittery, or miserable. I did have the slight nausea at first but took it w/ food and that was completely gone. The ONLY side effect that I’m having trouble dealing with is the sweating! But on the other hand I’ve noticed that as the days on the med. goes by the sweats are easing up. I can move and clean. I can just enjoy my life again. I take the Savella along with Vicodin ES and I’m very greatful to this medication. Ask your Dr. for the samples of it OR call Sam’s Club pharmacy7 or Cost Co. because they are by far the cheapest with their medications. So for those without insurance, which is me, you can get Savella 50mg for a month supply for $66.78 and that’s for the name brand so I’m sure generic is even cheaper. I hope that everyone has the great outcome that I’ve been blessed to have on this medication. Good luck to you all.
Missy M. 44yrs. old in Northern Ky.

August 2, 2010 at 11:40 am
(188) MissyM. says:

I forgot to add that I took Lyrica and put on 62lbs! And now with Savella I’m able to exercise again and hopefully take this weight off. I was also on Cymbalta but that made me stay on the couch or in bed, all I wanted to do was either cry or sleep. I’m not depressed and I think that is why the Cymbalta made me feel that way. So stopping the Lyrica and the Cymbalta and going back to my Vicodin ES and the new Savella I’m up and ‘running’ again. I’m enjoying life again. Ok, I’m done. Best wishes everyone. Missy M.

August 4, 2010 at 12:18 pm
(189) Jill in WV says:

I am on my 12th day of Savella. I was on Cymbalta and it did help but had side effects. The withdrawal was horrible. I feel good on Savella, but as my dose increases, so does my nausea. I don’t have any sadness, depression, just nausea. I think Cymbalta is a dangerous drug and glad to be off of it. The scarey part of Savella is reading all the articles on wanting it taken off the market. I am not near as tired. I sleep much better. I have been on Ambien for years to sleep and when I was on Cymbalta it really seemed to make me nervous at night. I am 65 and was diagnosed in 1994 with fibro. For years I was on Vioxx and it worked so well. However at the end I did have a small stroke with no after effects. I guess I have high hopes that this will make me feel like it did. I also take Mobic and would hope that maybe I can go off of it after this is in my system. I will follow up when I have been on for a couple of months

August 5, 2010 at 11:43 am
(190) Wildheart says:

Hi Guys and Gals, It seems I may have been taking Savella longest in this chat room, about 8 months now. Was very aprehensive initially because it is a SNRI. My only depression secondary to pian from fibro dx 2 yrs agao, and 2 herniated disc in my back. It was very difficult in the begining due to side effects Nauseausness, constipation (Phenergan, and Miralax I find the BEST to help with these two side effects) The KEY HERE is to wait it out, if you can. Give it at least a month,relief you may feel sooner I did within a week, has gotten better with time. But side effects will GO AWAY. Occasionally I may need a phenergan, An dI take Miralax daily. There is a generic for Miralax if cost is an issue. I am also a Physician Assisstant who has been leveled by these 2 disorders. But I will absolutely say it has helped me tremendously. MY Proof is I stopped taking it about 2 weeks again in some fear of the antidepressant property. Which I’ve come to learn people with fibro have hypersensitive nerve responses and the SNRI comes this, and has less constipation effects then Cymbalta which alos made me a Zombie I might add, and Lyrica caused edema hands and fett plus weight gain. Quit both. Savella has helped me more then anything, I am much, much more functional. I sometimes take a Zanaflex at night(Muscle relaxer) when a harder day then usual. And If I need to maily from my back one or two Hydrocodone daily. I’m in great hopes that soon I wont need the narcotics because I am having a series of injections which are helping my back alot. But Please dont be afraid, and dont give up on the Savella, its the best thing we’ve been offered. Also I would not recomend being on cymbalta and Savella at the same time. @ antidepressants I believe dangerous.Savella hasnt affected my head as Cymbalta did, its just simply calming the muscle pain and spasms. Good luck to you all, and God bless! And Thank You for helping me not feel so alone.

August 9, 2010 at 1:30 pm
(191) Tim says:

I just started the sample pack of savella on friday. So i’m on my 3rd day. I feel nauseated and i feel sad. Last night was kinda bad i work up sweating and felt a lump in my throat sensation. Im kinda constipated and when i pee it burns. Just called my doctor he told me to hang in there. I am 30 and if the fibromyalgia pain goes away i will be fine and dandy. Good luck to all!

August 9, 2010 at 2:08 pm
(192) Phillip Elmore says:

5 1/2 years with RSD/CRPS and I have tried virtually everything. Getting the best pain doc on the east coast kept me at work for the first two years. After $280,000, I still rely on 300mg oxycontin every day just to function. Since I can not work, I had to give up my massage therapist. It took two years to find him. My doc has been trying to get me to try the Savella for a year. I am just scared to try anything new as I have tried everything and have had some very strange problems. I finally gave in and agreed to try this new drug. The honest and varied responses on this web site was a major player in helping me make that decision. Although I am not diagnosed with Fibromyalgia, the symptoms and therapies overlap quite a bit with RSD. I will respond again in two weeks and hope it helps those suffering from this nightmare. Phillip Elmore

August 9, 2010 at 7:26 pm
(193) JudyDW says:

Savella did not help me – tried it for 5 months. Though did get some great sleep the first week. Lyrica gained lots of weight. Cymbalta did nothing. Have tried everything I hear of for Fibro with no success so far. My Dr will let me try anything, but he will not give me sleeping pills and nothing stronger than hydrocodone 7.5 Will try the supplements again D, B, Mult, fish oil, and magnesium – as several others have mentioned them. Someone mentioned a compounded drug Nahrexone – has anyone else tried this?

August 9, 2010 at 7:42 pm
(194) JudyDW says:

Sorry I misspelled the drug the name is “Naltrexone”. Anyway has anyone else tried it?

August 12, 2010 at 9:53 pm
(195) sara klee says:

i was never told the side effects of savella and i nearly died. severe sweats day and night suicidal thoughts nervousnous trouble thinking no sleep. i had to become my own doctor after 4 visits to er and many to a clinic, you would not believe the stuff they doled out to mask the symptoms which were sreotonin sydrome all along. oh my God never ever take this drug please sincerely sara klee who is just getting her life back after 2 months of excruciating headaches that almost made me jump off a bridge this drug is so new they have no idea of long term effects i can only pray

August 20, 2010 at 1:48 am
(196) elisha (30) says:

I was recently diagnosed with fibromyalgia. I have not taken any medications prior to Savella. The symptoms I have been experiencing have increased to the point that I am no longer able to function at work or home. My Doctor has put me on Savella, and I am using the trial pack. I feel a improvement already!!! I am so excited, I have not felt this good since high school. My husband has already noticed a difference! My ability to function has improved! I have energy and my mood has improved! I just pray this continues, it has worked for me. I only take this medication, its all I need! I have only had 1 side effect so far, a couple strange dreams. However, was never able to remember my dreams prior to taking this med? Feeling great and praying this continues! Good Luck to others on this med. I noticed a trend in bad side effects from this medication, related to taking other medications with it, or stopping other medications while starting it. Hope this helps!
God Bless

August 21, 2010 at 5:57 pm
(197) Ramona says:

Just started day 4 of Savella. I am newly diagnosed and this is the only medication I have been prescribed. I am glad (sort of) to see that others say they have a general feeling of sadness with this. I have been pleased to see that so soon into beginning this I already have an easier time getting up and around in the mornings, but geezzzzzz this depression. Not sure if this is the way to go but I will complete at least the two weeks sample I have.

August 25, 2010 at 9:50 pm
(198) Nikki says:

On my 3rd day of sample pack. Experiencing a bit of nausea and headache which is nothing new. This was rx’ed for depression I don’t have fm. I have felt like my brain has had too much caffine and my body hasn’t. In the evening I feel disconnected and uninterested and my anxiety returns. So we will see. I will get my magnesium and other vitamins checked out. Another side affect I have felt is like prickly skin hit and cold at the same time. So bottom line is in the morning I am in a good mood and have no back pain. I’m almost gitty. Then the afternoon comes and blah. Hope to all. Everyone reacts differently to meds.

August 28, 2010 at 10:42 pm
(199) Sammie says:

Hi all, I’m 43. Hubby and I just relocated to a new area and I had to find a new pain specialist. Today was my first visit. For the past several years I have been receiving treatment for 7 herniated discs (4 cervical & 3 lumbar), scoliosis (58 degree curvature) along with depression. I’ve been on vicoden for pain, flexaril for muscle spasms and was recently prescribed effexor for depression. The relief from the vicoden & flexaril is minimal at best. And the effexor, well, I think it made me even more depressed, bordering on suicidal. The new specialist today added fibro to my list of dx’s (which I have long suspected but wasn’t able to find a knowledgeable Dr). I was told to stop taking the effexor and to start taking the Savella today. I hope there isn’t any adverse affects to stopping the effexor so abruptly. I feel like I’m grasping at straws, desperate for some signifigant pain relief. Praying the Savella makes a difference. Prayers for everyone!

September 7, 2010 at 2:46 pm
(200) Kathy L says:

I have been on Savella for 3 months. I am so amazed that my energy level has returned! I was on Cymbalta for a year and gained 12 pounds, even though I worked out every day. I finally figured out it was the Cymbalta! I have not gained weight on the Savella, but it does have side effects. I do have to take it on a full stomach, or I get nausea. It does make it harder for me to sleep, but it is so WORTH it to me! I have been able to do so much this past summer! I used to come home after taking my kids to school and just go back to bed, I was so tired and in so much pain. Now I have a little pain, but my energy is BACK! Sometimes my heart beats fast and hard! I hope my doctor doesn’t try to take me off, because this drug has saved me!

September 7, 2010 at 4:54 pm
(201) KeLee says:

Thank you all for your comments…it was very helpful to me. I was just diagnosed with fibromyalgia after having symptoms for years. Doctor put me on Savella 2 weeks ago and I noticed a difference the next day! After 2 weeks it just keeps getting better! Yes, I still have every symptom to some degree but they are so much less frequent and so much less severe. Savella has definitely helped me and for all of you who are afraid to try it, I highly recommend giving it a shot. I’ve had no side affects from it and even if it doesn’t make me 100%, the difference so far seems very worth it. I’m looking forward to more improvement as I’m on it longer. Praying for all of you who are still suffering.

September 7, 2010 at 9:21 pm
(202) Lona says:

I just got my2 wk pack of Savella today. The first thing I did was get on the computer to read about this drug. I’m still not sure if I want to try this. What I have summized so far from reading everybody’s comments is the majority of people are on other medications. Thank God for Elisha and maybe 2 other recent comments that they are only taking Savella and this is the only thing there taking. Elisha I would really be interested to hear your thoughts on this medication after a couple more weeks of taking it.

September 8, 2010 at 2:43 pm
(203) Irene says:

First off, I received my 2-wk titration pack today. New doc in new town, after going over every test I’ve had done in the last 2 years, thinks FM is best fit.
Previously have tried Flexeril as a sleep aid, and neurontin for the pain. Neither helped. Not big on narcotics… as I have 2 children and don’t feel like getting a DUI while taking them to school.
I’m surprised at the amount of people complaining about side effects, then turn around and list a bunch of other stuff they currently take.
Drugs effect everyone differently. The more you take, the more side effects you’ll get. Quitting one to start another will produce side effects, from both angles.
I’ll be more than happy to keep y’all updated on a drug free person’s take on it. Well, we don’t count coffee around here! :) Best wishes to you all.

September 8, 2010 at 9:49 pm
(204) Kris says:

I took Lyrica for about 2 weeks and I gained weight almost immediately and didn’t see any changes for the positive. I have been taking Savella (sample pack) and I’m on my 2nd day of 50mg and I feel like I can do more activities but I am still with pain. I have lost a couple of pounds and I’m not as hungry but it is making me sweat like a pig and my eyes feel sensitive to light. I’m going to keep trying to see how it progresses I am hopeful. I will keep you posted.

September 12, 2010 at 4:41 am
(205) Bill says:

I have severe Fibromyalgia pain, shoulder damage and back damage from Penicillin overdose Chronic fatigue and depression. Also a host of related minor problems , I have taken a ton of medicines and at best they help the pain for an hour or 2 and at worst do nothing. I bought a prescription of savella but after reading of all the dangers I decided not to take it. The only thing that ever helped me was to get out of Ohio about 85% humidity and go to Arizona about 15% humidity . I have decided to go back again and if I am better again this time I am moving out there. Good luck to all of you and be careful of doctors, the good ones are overworked and have too many patients and the bad ones just don’t care.

September 21, 2010 at 10:03 am
(206) Sammie says:

After taking my two week beginner pack, I will NOT be continuing with the Savella. I received absolutely NO positive benifits from this med. The only thing I got from it were intense side effects. The nausea was miserable after every single dose, even on a full stomach. The sweating was absurd. I experienced some of the most distressing dreams of my life. My mood became more hostile with each day on this med. AND my insurance will not cover it. No sense in throwing away good $$$ on something that (for me) has ZERO positive benifits.

September 23, 2010 at 10:54 pm
(207) JennyGirl says:

Was suppose to start the 2 week titration pack tonight. However, after reading some of the comments not for sure if I want to take this med. Does anyone know, if you start the medication can you stop cold turkey or do you have to wean off? This may be the determining factor as to whether or not I start the medication.

September 25, 2010 at 8:21 pm
(208) Sammie says:

JennyGirl, I took my initial 2 week starter pack and discontinued at that point. I didn’t feel any adverse effects from stopping it.

I just met with my Dr again today and we are now going to try Cymbalta. It’s got some pretty crazy side effects too, so we shall see. But the Savella gave me absolutely no relief.

October 3, 2010 at 4:54 pm
(209) EllenB says:

Savella has worked wonders for me. Not only does it have a huge impact on my pain levels from nerve pain and inflammation, but it has suppressed my appetite so much that I’ve lost 3 clothing sizes (even while on Prednisone, which gives you a raging appetite) and I haven’t been sleepy at all (I was very sleepy and gained 30 pounds in 3 months on Lyrica). It’s worth trying!

October 4, 2010 at 2:46 pm
(210) Lisa E says:

I was recently diagnosed with fibromyalgia and started Savella 5 days ago. So far the only side effect has been a little bit of nausea, but if I take it on a full stomach I am fine. It is the only medication I take other than Relpax for severe migraines. I am already feeling a difference in the mornings, and I seem to be sleeping better at night and have m ore energy in the day. I have not gone more than 3 days without a migraine for over a year now, and I am hoping Savella really helps with the headaches. My mom has had Fibromyalgia for over 20 years now and has had a lot of side effects from the all the medications. Now she refuses to take anything and is always in pain. I am hoping this med works so well for me that she will try it too. Good luck to everyone here…

October 9, 2010 at 12:00 am
(211) Karin says:

I have a great team. my regular P.A. and a neurologist who are both brilliant and no-nonsense. I was in severe chronic pain for 7 months! I was ready to check out when after exhausting every other option (tests, MRIs, x-rays etc.). My P.A. put me on Neurontin and Soma for the muscle spasms and nerve pain. That helped tremendously. Then I visited my neurologist who asked if I’d ever been asked by a physician about Fibromyalgia. He started me on a 4 week titration of Savella. After one week I was already feeling relief. Now, I’ve been on 50 mg. for about a week and still have some mild to moderate pain if I overdo it but I am back to myself again! I am eating correctly and exercising as well, which is something I couldn’t do and lost 24 lbs. Yes, there is some loss of vision or blurry vision but it comes and goes. I have no other side effects other than I’m grateful to live again and be future oriented!

October 9, 2010 at 8:50 pm
(212) babbyla says:

I woke up unable to move 10 years ago. After a year of emergency rooms and tests, a Dr. put me on 200mg Imipramine HCL nightly (even though he thought it was all in my head and I should just get out with my girlfriends more). I tried the medication and it brought me back to life. I have tried to gain more funcionality but have found that nothing worked as well. I am phasing off the Imipramine HCL (my life-line for so long) and trying Savella. We are hoping it helps with my depression in hopes of gaining more ability. I forgot how bad FM is without any help. I am toughing through and have been on the titration pack (gradually increasing the dose) for 8 days. I am barely able to move and hope the Savella kicks in soon. If not- the Imipramine HCL worked wonders for me!!! and I can always go back to that. I am also exauhsted and have been having vision problems on the Savella.

October 11, 2010 at 9:47 pm
(213) JudyP says:

I just added a small dose 75mg 2x per day of Lyrica to 100mg of Savella per day, and am doing better than on either alone. I had suicidal thoughts on Lyrica 300mg, but good pain relief. My mood, energy and sleep were better on the Savella. It took a little convincing of the insurance company, but so far, so good. I had to get off the Lyrica before I was willing to try a smaller dose, though. Pain is a good motivator. Cymbalta put me to sleep all the time, as did neurontin and elavil.

I do have to say that I can’t be sure that this will continue as I tend to have a “honeymoon” period with most of these pills: I’m just five weeks into the Savella.

Oh yeah – the sweating with Savella was horrible at first, but is now diminishing. I also lost all 12 pounds of my Lyrica weight gain, because I have a much diminished appetite now.

October 15, 2010 at 3:12 am
(214) Blake says:

I just completed day 4 of the Savella titration pack. I have been in increased pain since taking the very first pill with no signs of improvement. I am experiencing nausea, stomach pain, facial warmth and red skin that looks like sunburn, increased sweating, dizziness, increased difficulty falling asleep even though I am taking Ambien, decreased sexual desire, severe pain AND swelling of my testicles, difficulty urinating, red spots under the skin, and itching…

I could add blurred vision but that was already ruined by Lyrica. For those of you experiencing blurred vision, you might not be aware that it is a permanent condition. Lyrica permanently blurs the lenses in your eyes, requiring cataract surgery to repair. It will cost me $2300 per eye to repair the damage Lyrica caused. My guess is that Savella is also damaging your eyes if you are experiencing blurred vision and if you are, it’s already too late to undo the damage. Quitting the medicine won’t bring your vision back…

I plan to stop in to see my doctor tomorrow and talk to him about these side effects, but I don’t see any good reason to continue increasing the dosage for the next two weeks. I was seeking pain relief. Savella is increasing my pain and adding to my problems. How do these drugs get passed the FDA? Once again, I am disappointed…

October 18, 2010 at 5:25 pm
(215) J. Parker says:

I am a 55 year old female that has had signs & symptoms of fibromyalgia for 3 years. This is my first pharmaceutical intervention for fibromyalgia. I am on day 5 of the “sample” pack and can honestly say that it has proven to be a “miracle drug” for me. I sleep better, my pain has decreased 90%, I have improved mobility, decreased hot flashes, decreased swelling in extremities, increased energy level and certainly an improved attitude. I have not felt this good in longer than I can remember. I never knew how bad I felt until I felt good again. The greatest hurtle will be whether or not my insurance will cover it.

October 20, 2010 at 10:34 am
(216) Sammie says:

I’ve been on Cymbalta 30mg 2x/day for almost a month now. I am pleasantly surprised with considerable relief. The everyday, chronic muscle/nerve pain is much more managable. I can now tollerate my cat jumping into my lap, which before caused intense pain. Even the wagging tail of our dog touching my legs as she walked by would bring me to tears. And an additional plus is that it’s also helping with the chronic depression that I’ve struggled with for years. I have experienced NO adverse side affects from the cymbalta. I do still experience spine and neck pain due to 7 herniated discs but even that is comfortably managed. AND our insurance (United Health Care) is also covering the Cymbalta. Major PLUS!

October 22, 2010 at 7:30 pm
(217) Shan says:

I was diagnosed with a brain tumor last year after having severe muscle pain, fatigue, migraines, etc. The tumor hasn’t grown very much, but no one could figure out what was wrong. I was believed to have MS and was even sent to MD Anderson (which was a waste of time in my case). Finally saw a rheumetologist who diagnosed me with FM. Whatever is wrong with me, I did start taking Savella over a month ago. I started with the 2 week trial pack which increases dosage gradually. Dr recommended HALF of what was recommended in pack. These were my initial side effects:

Day 1 – horrible disgusting dreams. Sweating. Did not sleep well.

Day 2 – no horrible dreams. Night sweats. A bit better on the sleep.

Day 3 – Feeling better. A little light-headed. Nausea. Emotional.

Day 4 – Much improvement in energy. Went shopping. Slept better that night.

So far I am sleeping better at night and have even taken a few out of town trips. The trick for me is to take dosage an hour before the evening meal on an empty stomache. Otherwise, I feel sick to my stomache. It must be taken at the SAME TIME daily. When I did miss a dose and took it later that night or the next morning, I could feel the FM pain gradually returning and I would get sick. The pain has not 100% disappeared, but I do feel like I have my life back. FM for me comes in cycles, as I’m sure it does for all of you. At least not I don’t feel like staying home all day.

On a side note, I did have my Vitamin D level checked last week and it was severely low. In researching Vitamin deficiencies, low levels can contribute to many of the symptoms we all experience with FM. I hope some of this information helps some of you in the quest to get your lives back to somewhat normal. I’m still not convinced that I have FM, but the Savella is helping my pain and fatigue. AND, I’ve even lost a few pounds!

October 23, 2010 at 9:52 am
(218) new_hope_4u says:

miracle drug .. I have tried it all and after taking Savella for 2 weeks and up to 50mg a day, now I feel great.
I’m still taking pain meds for disc problems but the FM symptoms have decreased 75 per cent.
Now if my insurance company will cover it I will be in good shape.

If you suffer from FM like I have for 10 years try this medication. IT WORKS.

October 23, 2010 at 11:22 pm
(219) kath says:

I have been on Savella for 3 weeks and can’t really say I feel much pain relief. However I’ve just been weaned from 8 months on Prednisone for a diagnosis of PMR – Polymyalgia Rheumatica.

I am curious to know if others have had that diagnosis or mis-diagnosis along the way. They now say I have fibromyagia but I wonder if this is just an “I give up” kind of diagnosis.

My side effects on Savella have been increased dizziness and very slight nausea…no big deal. I was able to loose 100 lbs while on Prednisone and have not felt an increased appetite on Savella.

Do you al think Fibromyalgia is really legitimate? I don’t believe AI suffer for any kind of depression nor do I think I have a lower than normal pain threshold. I have not really had much of an opportunity to discuss this with my llatest doc. My rheumatologist sent me on to a rehab/pain guy??? I believe some of you sond very knowledgeable about the subject. Anyone else been treated also for PMR?

October 27, 2010 at 9:56 pm
(220) Nita says:

I have been on Savella for 2 months now, at first yes it was slow going on getting my old self back again. They are treating me for Fibromyalgia & the pain is mostly gone. I am starting to feel good enough to go outside & work in our greenhouse. I had given up after going to so many doctors for 2 yrs trying to find out what was wrong with me. The last doctor sent me to a pain doctor, but I almost didn’t go. I was beginning to think it was all in my head. But I had ended up in the hospital with cellulius & the pain was real. So I went to the pain doctor & the first thing he put me on was Savella. But 2 months later I am happy to say I feel better & better everyday. 100 mg daily & I do praise the doctor & the medication. I don’t how long I will have to be on this, maybe the rest of my life but at 61 that is not too long. I will take it until the doctor tells me not too. My insurance did not pay for the first prescription but I got a letter from the doctor saying he was treating me for pain not a mental condition & the insurance is going to pay for it now. Praise the Lord!!

November 4, 2010 at 2:25 am
(221) Karen C. says:

After Savella was released, my Internist gave me a box of samples. He didn’t tell me anything about Savella except that it was for fibromyalgia. Let me warn you if you take anit-depressants that Savella plus the anti-depressants can cause a serious and sometimes deadly condition called Serotonin Syndrome. I have had this syndrome before when I have been on SSRIs and if I have been prescribed Ultram and Neurontin while I am on anti-depressants. A savvy pharmacist caught one mistake with a Neurontin prescription. Savella gave me Serontonin Syndrome. I felt all buzzed up like I was on 50 gallons of coffee. I was irritable, irrational, and could not sleep. The night I couldn’t settle in bed and “knew” that if I found a razor blade and cut myself I would calm down told me it was the medicine. I called a nurses’hotline and got off the medication. Savella can be dangerous. PLease talk it over with your doctor and pharmacist before beginning it.

November 16, 2010 at 4:37 pm
(222) Jenni H says:

Hi everyone. I have had fibro for 12 yrs, I was a bartender forever and worked 2 jobs most of the time. I’m now disabled with the fibro and osteo. (plus asthma and COPD just to make life more interesting), I have run the gammut of drugs, herbs, vitamins etc. The only thing that helped at all was vicodin and I used it sparingly. Last year some smartass dr decied I was an alcoholic because I had a few drinks to help with the pain. Fibro had become so horrific that NOTHING helped. Fibrofog, numbness in my hands blah, blah. Anyway the dr. took me off of vicodin and gave me Cymbalta. I ended up with a gun under my chin in June of ’09. I quit Cymbalta, it didn’t help and I blame it for the gun incident. Went to new drs. I ended up with the vicodin again. Altho vicodin helped,the pain was still there. I am now seeing a new dr. at the same office. Even tho I have told him that I have awful reactions to antidepressants he has given me a script for savella. Any of you out there that have no ins. Savella is from Forest Pharmaceuticals, Inc. Look up Patient Assistance Program on the web. You can get your scripts free. Get your dr. to fill out their portion and you fill out yours. Send it in for approval.So I’m waiting for the tri. pack to arrive. I have to say that I am scared witless about taking savella due to the results from other meds. But I have no choice, this dr. has also taken me off of vicodin. He said to try aleve! I’d like to see these drs. go thru the extreme pain we fibro suffers endure on over the counter pain meds!! So here I sit, nothing for the pain, waiting for a med. I’m scared to death to take.
God Bless all of you who have written in here. I Pray that
each and every one of you find whatever it is that will help you live a full life again. I’ll update after I start the savella. Until then Via Con Dios. ( mis-spelled I’m sure but means Go With God)

November 29, 2010 at 3:58 pm
(223) Jenni says:

Jenni H. I just started the savella packet. I am a very skeptical person because nothing else has worked for me. I have been on nuerontin, Lyrica (with 25 lbs. weight gain), cymbalta, and nortriptilene. The nortrip has helped better than any but I was still having ridiculous pain. So far, the savella really seems to be helping….not in near as much pain but the nausea is really a bi*ch….I hope i get used to it because the nausea is horrible but the pain is better…
I am also on Vicodin which is the only thing that gives me relief. My husband complains about my pain, the docs think I just want drugs…..it is horrible being a person with chronic pain. No one understands. I really hope this savella keeps up….I hope it works for you. I would also find a different doc. I finally did, unfortunately I think he my be a doctor feel good……

December 5, 2010 at 7:25 pm
(224) vitty says:

Rheumy gave me Savella starter pack last week for fibro which I have had for at least 8 years. Been through 12.5 mg, 25 mg 2x day. Tomorrow I am to start the 50 mg x 2. So far so good. Some lightheadness each time I upped dosage but I am sleeping more sound. Have had severe neck spasm for over a week, but it seems to get better. Doc gave me OK to half 50 mg dosage if it seems too much too soon. My bigges worry is whether higher dosage will cause constipation. I have had some vision blurryness but I have had that for a while due to a head injury last year.

December 15, 2010 at 10:47 pm
(225) Sophia says:

I am 26 years old, and I was diagnosed with fibromyalgia in October of this year. I am taking 50 mg of Savella in the morning and in the evening. Some days I am very nauseous and have trouble keeping food down. It has diminished the pain; however, the pain is not completely gone but more bearable. Before I was diagnosed, I was taking a muscle relaxer every night just to sleep. I was happy to have an answer for the pain, but unfortunately it wasn’t what I wanted to hear. My mother has fibromyalgia, chronic fatigue syndrome, and osteoarthritis. I work full time in an elementary school, and I am in grad school. I am trying hard not to let fibromyalgia affect the quality of my life!

December 22, 2010 at 5:40 pm
(226) angela says:

I have had chronic pain since I was 14; now I am 27. Since I am done having children and no longer breastfeeding, I wanted to try something for my chronic pain. I am on my second day od Savella and I feel worse than before. I have more pain, my heart is racing like crazy, everytime I stand up I feel like I am going to pass out, nauseous/reflux and in the morning my joints were VERY stiff. I am going to try for a week, but if this keeps up, I will definitely be getting off. I also feel more snappy because of the state I am in. I almost forgot to mention the horrible hot flashes! My face feels like I have a sunburn and gets extremely hot…I just feel better when I take a muscle relaxer or the very occasional pain pill. I just really feel like this is killing me as of right now…when I get up to do anything, it feels like my heart is jumping out of my chest and I am getting palpations. My doctor said just to be cautious as this is a common side effect, but I hate anything that affects my heart. I guess I was hoping for something to at least help a little since I have waited so long for help and it is disappointing.

January 2, 2011 at 3:21 pm
(227) Carrie says:

Savella is exactly as it is called. It really has saved my life and family. I habe been on Cymbalta and Lyrica and neither did justice. I mean, I still have days that I just want to give up, but when the weather can stay constant and now having Savella, I can live a somewhat normal life. Seriously, I can wake up and be in dire pain and my body is so stiff, and about two hours after taking the medication, I have much improvements. It has an energy boost to it like the other two medications do not and I think that helps a lot. So if the medication might cost more then the others, it is really worth the cost. I could not live a normal life for a year when the symptoms all hit hard and now after three different medications and ending up with this one, I can say its worth the extra price and helps

January 30, 2011 at 12:28 am
(228) rose says:

After being diagnosed with fibromyalgia I tried different medications. Cymbalta did not seem to work for me. It just kept me up all night and brought no relief for me. So my doctor switched me to soma & sulindac (muscle relaxers) which brought some relief, for about a week or so. Now Im taking lyrica, pain has been tolerable, up until 3 weeks ago so now im taking lyrica & Savella. I’m on my 3rd day of savella, I’m praying this does the trick. In a lot of pain & tried of the meds. Good luck to all. God bless.

February 8, 2011 at 5:04 pm
(229) Michelle says:

A participant for over 2 years in the US clinical trials – I can’t imagine my life without Savella, but I just got the shocking news that the prescription – even at Walmart – will cost me $289 per month!!!!!!

I can’t afford that – what on earth is there for an alternative?

Has anyone tried ordering it in Europe and having it shipped over – is that any cheaper?

February 13, 2011 at 1:25 pm
(230) Gary says:

I was only diagnosed with fibro about two months ago but have been in pain for 5 years. I started self medicating with aspirin 4 tabs 4 x a day. I finally thought I should see a doctor. I’m on ultram and vicodin and sleep aids. I tried cymbalta NG, lyrica NG, neurontin NG. I just started savella 6 days ago and I feel better already. I now have some HOPE, again.

February 16, 2011 at 7:56 pm
(231) Marilyn says:

Fibro sufferer for a 25 years. Seems to get worse the older and more stressed out I get. When I turned 50, it got really bad.I threw my knee out and then the fun really becan, Myofascial pain syndrom set in with extreme fatigue. I read all I can about positive thinking. Negative thinking and self lothing will cause a lot of pain as we feel a need to punish ourselves. Prescriptions. med always disagree with me. I love the Lawyer commercials for prescription drugs users who have had horrible side effects, fosamax especially. Atlernative medicinee is my choice. I feel better when I take a lot of good quaility supplements. I have added milk thistle for my liver and a healing oil for candida. Waiting to see results, Today I saw a new doc for a cyst on my back. he gave me a trial for the new one Savella. Okay I am desperate and willing to try it. Around 75. 00 from walmart. Read all the comments. My gut is telling me no, I did take one dry mouth already. I i do not think my body in this unhealthy state needs this drug, I need antioxidants, good nutrition good thoughts. oh and now I feel a little light headed.

February 18, 2011 at 9:33 pm
(232) PeggyAnn says:

I am 50 and recently switched from Effexor 75XR (after about 10 years) to Savella 50mg 2x day. I am so depressed, emotional, crying, irritable, no desire to get up and out at all and I am a salesperson. They increased me to 100 mg in the am and 50 in evening.

Anyone else had any similar problems and did they clear up?

February 25, 2011 at 10:58 am
(233) seaweede says:

I have had FM for more than 15 years and have just “lived with it”. Finally yesterday I was in so much pain I didn’t want to get out of bed. That scared me so I called my doctor. She prescribed the triation pack of Savella. I have never taken any rx for fibro so this is my first experience. I too, like many of you, am scared to death of the side affects. I refused to even try Lyrica or Cymbalta because of the crazy warnings. The only other meds I take is birth control so I’m thinking I may not have it too bad since it will be the ONLY other medication I will be taking and I’ve gotten desperate. I took the first pill last night and had an awful time sleeping. Took my first of two this morning and had a little diarrhea but so far nothing else. I really hope this works but at the first sign of me feeling wonky, I’m done! Will post more as I continue with the meds. Good luck everyone with this horrible, debiltating condition. It down right sucks!

March 4, 2011 at 1:09 pm
(234) lorraine says:

I have been taking this Savella for 8 days.. tell me I am always so sleepy… Is this normal…

March 4, 2011 at 7:35 pm
(235) Seaweede says:

Okay, day 9 of savella and I have had absolutely no side affects! I think it’s because I’m taking no other meds. I’m not sure I am feeling so much different since I’ve had severe back spasms since before I started Savella. The spasms are decreasing so maybe I will notice more of a difference when they’re gone. I know it takes 2 weeks to build up to the full affect so I’ll write more then. Hope everyone else is doing okay on this!

March 9, 2011 at 1:49 am
(236) Sandyl says:

I have tried to wing it, with just taking advil up until this past year. I keep having Er visits with what they say are strokes, then they rule that out by ctscan. then say I am having seizure like symptoms. I am like the person above who says they have a lot of these symptoms without meds. Where I am, I suppose I have been black listed or something but the last 20 doctor visits I have had wont give me any thing for pain, they insist on my taking neurotin which after reading on the net, some people got permanent twitches, I was afraid to try it because I jerk before I go to sleep anyway, i did start taking loranzepam after the last er visit, he said it would controll the seizures, so now I am taking the ativan, and a muscle relaxer, which is not helping at all, my pain level feels like a 12 and times and that is when I have the seizurelike symptoms, of being very numb and weak, and my stomach convulses,
I dont know what to do, after all the side effects of these drugs I dont want more problems

March 15, 2011 at 4:30 pm
(237) Christy says:

I am about a week and a half in at full strength. The nausea has been as bad as a stomach virus. I have felt withdrawn and lethargic. I just had a major flair, so I can’t tell if it is treating the pain, or if the flair has just lessened. I am still taking excederin on top of Savella and Tramadol every day. I don’t notice a major difference in pain. I hope it starts to work soon, because I don’t feel like myself. I feel like a zombie with no motivation.
I have lost some of the weight I gained on Nurontin, which has stopped working for me. I wanted to go back on Lyrica, but my doctor wants me to try this for 3 more weeks.

March 20, 2011 at 9:22 pm
(238) Sandra Franklin says:

Just started Savella 3 nights ago. Praying it will help me. God bless all of you who suffer with fibro pain. There’s no way to make anyone understand how bad this thing is unless they suffer with it themselves.

March 24, 2011 at 7:02 pm
(239) suzie says:

I have suffered with pain since 2006, was diagnoised with fibromyalgia in sept of 2010. My Dr. put me on Lyrcia, 150mg 2 x a day. It just has not helped with the pain I have, and it makes me completely loopy. I can forget what my last conversation was about within 5 min. I just hate it. Today my Dr changed me to Savella, the foil pack. I start tomorrow while decreasing the Lyrica. I am very sensitive to any kind of medication, so I am already skeptical on this med working. Sure hope it does though.

March 27, 2011 at 7:26 pm
(240) Kathy says:

I’ve just completed my first week on Savella, biggest complaint as far as side effects is the hot flashes, but I did get a quick grip on them – knew from previous medication side effect that hot flashes can be combated with the herb “Black -Cohosh” – verified with my pharmacist that it wouldn’t interfere with Savella or any other meds I take. It has been a LIFESAVER – dealing with hot flashes is the pits, but now all is well. My Reumatologist said that most quit Savella before initial 2 weeks due to side effects — The period of adjustment to get your body use to the med is almost 2 weeks. I’m definitely looking forward to being on the full dose of the med, and seeing if I get the benefits of it that many have!

March 27, 2011 at 7:40 pm
(241) Kathy says:

For those that are just starting Savella – my Rheum. has me taking it only ONCE a day – at night to help with the nausea, she finds it works before for her patients to take only at night for the first week. I had NO nausea the first week at all, just started 2nd week, so taking it day and night now, yesterday was first day of that, so far so good!

March 29, 2011 at 8:27 pm
(242) Sharon says:

Everyone please check out the website Aboutlawsuits.com under the heading Savella-recall-urged-by-public-citizen. You will get to view the experiences of patients like myself who are suffering the long term side effects of Savella (15 months now!) some of us are dead from heart episodes. But some seem to experience relief – definitely worth your effort and time to check this drug out THOROUGHLY before you or a loved one take it!!!

April 3, 2011 at 9:01 pm
(243) nsquared says:

I was diagnosed with morphea(a form of scleroderma) and fibromyalgia in 1998. Had never heard of either, just knew I was in constant pain, had insomnia and barely had the energy to dress myself some days. My rheumotologist prescribed arthrotec, Ultracet, Ambien and eventually Cymbalta. Up until a year ago I was able to manage my pain and have a fairly productive life. Then my pain episodes seem to gain intensity and lengthen into 5-7 day cycles. Three weeks ago I was prescribed Savella and given a the 2 week triation pack. I was “weaned” off the Cymbalta and instead of taken arthrotec was prescribed twice weekly injections of Toradol. The first week I experienced nausea, dizziness, and lots of crying for no reason. My pain was not noticably better but did seem to feel a bit more energetic. When I reached the 50mg. twice daily stage, the nausea and dizziness became unbearable plus I started having anxiety attacks which began with my heart pounding in my chest and ending with me stretched out on my bed shaking and crying uncontrolably. The dr. put me back to 25 mgs. twice daily. The nausea and dizziness are rare but have developed problems with my eyes. The depression and anxiety have both increased to the point I feel out of control. I have also experienced episodes of feeling like I want to start a fight with somebody, anybody! I keep being told to give the Savella time…..but my quality of life seems to be decreasing every day. Plus, my insurance will NOT pay for the Savella. My dr. is giving me samples for now until we see if it will work. My question is this…..if it does turn into a ‘miracle’ drug how will I pay for it??? I’ve had to take so many unpaid sick days this month that I’m not sure how I’ll pay my other bills. THAT certainly doesn’t help the anxiety!

April 25, 2011 at 10:36 am
(244) Paula Westman says:

I have been taking Savella for about six weeks—WHAT A DIFFENCE! I have been seein my doctor for th last three years or so with foot pain. She kept telling me I had heel spurs. About six months ago I woke up and had a hard time even dressing myself. I was having muscle spams randomly throughout my body. I had my husband take me to see the same doctor. She did bloodwork and said I wa having symptoms of Fibro, but the blood work didn`t ssay I had it. I went back every month for blood tests until my body finally showed her that I indeed did have fibro. My doctor began treatment of Savella with the first evaluation and not an actual diagnosis. Within a week I went on many tropical vacations (sweatig horribly!), had constipation and dizziness. I will take any of those side affects any day! Which I still have and am told they will probaly not go away!
I am 42 years old and need to live life, like I did five years ago. Very active–walking and riding my bike! Hopefully this summer I will be up to it!
Keep your chin up, get up every morning with a smile and keep moving!

April 28, 2011 at 3:18 pm
(245) Ouch says:

Seems you either love this drug or hate it. People with high blood pressure, or frequent anxiety would not do well on this drug because it seems to aggrevate your heart.
I do have to agree with the other knowledable members that taking it with a bunch of other medications brings on more severe side effects.
I’m only 27 years old and deal with fibro, osteo, AND hepatitus C. Can’t forget BiPolar and daily anxiety. My physical conditions all leave me in constant severe pain and CFS. It’s hard to keep your head up every day even if my fibro isn’t too bad, something else is causing pain. I only take gabapentin for my fibro, works pretty good, but tolerance builds very fast. My SNRI Effexor doesn’t seem to help pain issues like the others claim. Also on norco and mobic on a temp. basis until I see new pain doctor… All this constant pain, tiredness, and depression will easily have me go back to heavier narcotics. Dependence is a given, but they are the only medications that give me energy and relief. ugh… Light massages, water exercise, and right vitamins/supps are key too.. I did find a great P.A. who has been amazing in this craziness. A good doctor is mandatory guys…. I hope you all are having a low-pain day, thank you for giving your results with this med as well as your stories…. you give me hope. <3

April 30, 2011 at 10:45 pm
(246) Mel says:

I’ve had firo for years, and went to my rheumatologist yesterday who gave me the 14 day titration pack. I’m a little scared to take it even though I’m in the middle of a terrible fibro flare up – I’m currently on no medication so wondering if anyone out there who was not on any other medication tried or is currently taking Savella and what your experience has been.

May 7, 2011 at 2:04 pm
(247) K. Hughes says:

STARTED SAVELLA 1 MONTH AGO: It has stopped the aching and I am starting to sleep better finally, but this stuff is harsh! I hope I get to feeling better generally and the side effects start to minimize – headache, nausea, generally bad mood. I now feel all the other sore places, but they are not so bad since the fibro aching has stopped. I have Medicare part D and my co-pay is $92 a month, so hope it is worth it. Time will tell.

May 13, 2011 at 10:13 am
(248) Kate says:

Savella is the most recent in a 12 yr. search for relief to RSD pain (reflex sympathetic dystrophy) & got to say it is not a long term answer for me. Nerve blocks, biofeedback, morphine & its relatives, did not compare to the relief I had on a combo of Lyrica + Cymbolta. My doctor knew what she was doing with that mixture, but after 8 yr. I noticed memory issues with the long term use. I’ve used Savella for about 14 months with minimal pain relief & now intense stomach pain for over an hour after taking . . . . hope there is something else I can try so I can stop the Savella.

May 13, 2011 at 11:58 pm
(249) OCCH says:

I’ve been taking savella for almost 2 years, and I have to say is a miracle drug. I tried cymbalta and lyrica, they didn’t do a thing for me.

May 30, 2011 at 4:02 pm
(250) Brenda says:

Savella made me dizzy when first started taking it. A little nauseated so I learned to take it with food or after a meal. It caused me to lose my appetite. Had ringing in the ears but that eventually disappeared. My eyesight has worsened since starting Savella.

I took Savella for six months before most of my pain subsided. My upper arms and upper legs are less sore and I can work outside without experiencing extremely sore muscles the next day.
The pain in my buttocks all but disappeared since being on Savella.

All the side effects are worth it for the pain to decrease. I can tell that it’s acting somewhat as an anti-depressant with me.

I’m going to try to taper off Savella slowly, down to 50 mg a day to decrease the sweating.

My Savella prescription cost me $60 out of pocket each month using Health Advantage Insurance.

Hang in there if you can because I don’t have as much pain as I did before using Savella.
However, the poor appetite and the extreme sweating have increased

June 17, 2011 at 9:30 am
(251) Mary says:

I just saw a new rheumatologist yesterday after seeing the same dr for the last 10 yrs. Who by the way seemed to loose interest in my condition as the yrs passed. My new dr gave me samples of savella that i am to start tonight. I too tried lyrica which was horrible!!!!! They need to advertise on tv what the insert says “Lyrica can cause some people to feel high”!!! i also tried cymbalta but after a fews days, my eyes were dialated! Isn’t that a bummer! Didn’t read that as a possible side effect! It also made me feel like i was moving in slow motion. I’m really excited to try the savella in hopes that i will get some relief from the pain but not so sure about all the side effects i’m reading about. The decreased appetite and weight loss sound great to me since i have gained 20 pounds in the last 6 months! I’m ready to start feeling better and doing the things i used to enjoy!

August 11, 2011 at 1:02 pm
(252) seaweede says:

I’m back. After taking Savella for 6 months at 200 mg a day, I feel fine. (!) The only noticeable side affects I feel are the flushing and occasional nausea. No elevated BP or heart rate. I have lost weight though-without trying. I was 122 when I started now down to 113. I’m not complaining, just weird for me even if I eat ice cream every day, I don’t gain. I have noticed my eyes getting a little worse. The fibro is more tolerable now and seems to be working well for that. I’ll give it a couple more months to see if my BP raises and if my eyes get any worse. If either happens, I will taper off and stop. I can manage the fibro but not the loss of sight!!

August 24, 2011 at 12:07 pm
(253) Lindsay Lohann says:

Fibromyalgia attacked my body more than 10 years ago after knee surgery. I was in a wheelchair for about six months, and I used a cane for another six months. I did not even know how to walk anymore. I fought the fibromyalgia with a lot of pain pills and tears. I was on so many medications that it damaged my stomach lining. Learning to break the cycle wasn’t easy because it was painful. It caused tiredness and depression. To this day, I am no longer on meds, and I live a new life with a new career. I have no more depression. It tries to creep in, but I fight it off through prayer. I have bowel problems, this pain that pain, etc., etc., etc. I find that when I help others and talk about it, it brings hope to others. Learning to stop the cycle is a battle. But there is hope.

October 15, 2011 at 3:46 pm
(254) Jeanne says:

I was diagnosed with Fibro 18 years ago and have gone up and down with it. Lost my son 5 years ago and the firbromylgia came on full force bring with it Lupus and RA. I have taken Lyrica until it just stopped working, Lexapro and after 18 months quit helping. I was then on Cymbalta which wasn’t helping after awhile. I am now on day 11 of Sevalla and I have noticed that I come fully awake in the morning, not as much stiffness but the depression is severe. That I think comes from getting of of the Lexapro so hoping the
Sevalla will soon help with that. I have some nausea at times but nothing I can’t handle. My problem is the cost, I am on disability and can’t afford the prescription part of medicare. I find something that looks like it might help and can’t afford. it.
\

October 25, 2011 at 11:17 am
(255) Joni says:

My Dr. started me on the Savella very gradually. Using three of the 2 week triration packs instead of one. Therefore instead of the 1st dose only being for one day, I took the 1st dost for 3 days. The increased dose for the next 3 days, I take for 9 days, etc. It took longer to go to the full dose, but this really decreases the side effects. My Dr. had been starting people with 2 of the packs instead of 1, but then decided to start people even more gradually with 3 packs to decrease their initial side effects. I am having no side effects and am feeling much better. Had tried Lyrica about 7 years ago for FM but stopped after a couple of months due to side effects. I have taken no other antidepressents so maybe this is why I got along so well with the Savella. Too many drugs in your system counter-act one another.

November 2, 2011 at 9:08 pm
(256) Nina says:

Two years ago, I was diagnosed with fibro. The first time I took Cymbalta, I felt like my head was going to explode. However, I gave it another shot, and over the time that I took it (about a year) it helped my pain, but I developed constipation issues, night sweats, and insomnia. Earlier this year, it seemed that all the pains were coming back. Plus, when the doctor doubled my prescription, the insurance company wanted to charge me double for it. I couldn’t afford it. Finally, my doctor switched me to Savella. I am up to two 100 mg pills a day. It is costing me $70 a month with insurance. I have not experienced the blurriness or dizziness that some have, but I often have to take ibuprofen for headaches. I learned that I can’t take Savella on an empty stomach or I’ll get nauseous. I am sleeping better and I haven’t experienced night sweats or fibro fog and tiredness. Constipation is still an issue. Using Dulcolax and adding fiber helps. Lately, I have felt like I am more easily frustrated, so it may be affecting my mood. But, I also have to admit that I haven’t been exercising, which I know helps. Make sure you’re getting enough Vitamin D. I take 2,000 IUs a day. None of us are going to react to the same medications the same way. I am going to keep on the Savella for now. I wish you all good luck with your mediations and pain management.

November 2, 2011 at 9:27 pm
(257) Nina says:

One more comment from me – I have had some stomach pains lately and I seem to often get a rumbling in my tummy immediately after eating. But, I’ve been taking a probiotic/prebiotic combo as soon as it starts and it really helps calm things down. Multivitamins, fish oil (omega-3), antioxidants, caclium/magnesium, vitamin D, vitamin C … these things are just as important to include with your prescription medications.

November 27, 2011 at 6:32 pm
(258) Michele says:

Hi! Reading these comments didn’t make me feel so lonely. I have been on Savella for a little over a month now and never before have I ever had so many side effects on a medication. I have the nausea and loss of appetite but worse is the cold sweats and the hot flush in my face. My face is bright red, on fire for about an hour after a few hours of taking it and the sweats-my sheets are soaked when I get up in the morning. BUT- my pain is definitely better and if thats the trade off, I’ll take it! Hopefully the side effects will get better.. but if not, its annoying, but at least not in as much pain and not taking as much Norco, which isn’t working as well anymore either. I wish the best for all of you and hope you will find what works for you!

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January 18, 2012 at 10:22 pm
(260) Evette says:

I have been on Savella since December 2011, all I can say is that after trying many other presciption drugs in it’s place, this is the first time that I am finally feeling more like myself. It’s now almost 2 months and I feel fantastic!!!!

February 26, 2012 at 1:53 pm
(261) Patty says:

Just a warning for everyone on Savella…I tried the sample dosage packet back in May 2011…I was ok til day 7..i then had a horrible reaction during the course of a flight (I am a Flight Attendant) and could barely walk..the pain and swelling in my hands and feet were so severe I was rendered immobile and it was terrifying.I went to the ER and they had a list of my steady meds but I was too sick to tell them about the trials of Savella…I have been off work for 9 months…after every conceivable test I am still in pain but the Cymbalta they placed me on was tolerable…I tried Lyrica and sadly blew up 30 lbs. after 2 weeks of feeling great.For those of you mentioning VISION PROBLEMS from Savella..I woke up on Aug.7th with binocular double vision…every optho and neuro test confirmed a 6th nerve eye palsy Your eye will not move in conjunction with your other eye) that never got any better on it’s own (which they say is very rare) and I have been unable to drive a car or leave my house unassisted until this week as I just underwent surgery to remove the muscles and nerves on my eye and have them re-attached so that I can see again…I have had MRI’s,Spinal Tap,so many blood tests and nerve tests you can’t imagine and there is NO other medical reason in my body for any of this..so..not linking the timing of my illness and vision crisis to a little starter packet of Savella,my diet Dr. recommended it again to try to get the weight off of me from the Lyrica and Cymbalta…Well…WARNING to all of you…after the 7th day I again can barely walk or move and my newly returned vision is all blurry now…PLEASE be aware of these symptons I am sharing with you…I wouldn’t wish what I have been thru the past 9 months on my worste enemy…be VERY cautious of this med…I have been to hell and back so please pay attention and be aware and BEWARE…I wish you all wellness and true health!

February 29, 2012 at 1:55 pm
(262) carlene says:

IU was just told today by my rheumatologist that he thinks I have fibro along with MS and Rheumatoid Arthritis- he just gave me the titration pac of Savella- so I am weaning off cymbalta to start this- I would have never dreamed I have fibro- I always thought it was just a diagnosis that the Dr gave you when he couldn’t find anything else to call your problems- we had a long talk about it- I am very reluctant to accept it- but it is what it is!!

April 2, 2012 at 9:36 pm
(263) mom says:

I am trying to get off savella. horrible side effects. look it up first before taking. i havent slept for 4 nights.

April 2, 2012 at 9:38 pm
(264) mom says:

I am trying to get off savella. horrible side effects. look it up first before taking. i havent slept for 4 nights.also was on cymbalta and got off it to try savella. BIG MISTAKE.

April 12, 2012 at 6:23 pm
(265) maureen sheets says:

Have been on Savella on and off since 09. Was on it while working and it was covered by ins. Then retired and ins wouldn’t cover it unless the dr jumped through many hoops, finally started getting it…co-pay was $18.00. Then today I recieve my refill in the mail and for 3 mo supply, (180 pills) it came to $160.00… Stinks that I couldn’t even send it back so I have to pay for it whether I can afford it or not! We all need some help out here… It really helps me to function and have a little of a normal life!

April 25, 2012 at 11:47 am
(266) Louise says:

Cymbalta has helped me get back to my normal self. But and I mean a great big but I cannot afford $174.00 a month. What else can I use.??

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May 2, 2012 at 11:24 am
(268) Qcjiurac says:

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May 9, 2012 at 7:27 pm
(269) royce says:

I have been on savella for one month and the side affects were just like everyone said. Nausa was a big problem so I drank ginger ale and ate Murrays ginger cookies. It seemed to help nausa. Final stage with full dosage was the last straw and decided to cut back on dosage strength. Anit despressant part of meds did not work at all so I have been a nervous wreck and thoughts of ending it. All the other side affects seem to ease and go away over time. Now if arthritis would calm down. I still have acute pain in hands-shoulders, legs (knees) along with fatigue. Sleep at night is not any better. I wake all the time whenever I move. I just want a good nights sleep every once in a while.

May 11, 2012 at 8:15 pm
(270) lucidkitty says:

If you are on Savella alone-or with Cymbalta- PLEASE read about serotinin syndrome. It sounds like quite a few people here may have mild symptoms of it. Every drug you add, you must research the interactions. Savella and Effexor can be a nasty combination. These drugs all have very very individual effects, and side effects. The same things do not work for all people. It sucks. I’m sorry.

I hurt so badly right now I want to scream.

If you are having trouble sleeping- ask your MD about amitriptyline at night, or gabapentin at night. You may need a bezo like ativan for a short while.

Drinking with these does not work- at all. So if you are, sorry but you have to stop. STOP. AT least for two weeks (if you can’t then address that issue) and see how you feel.
NO caffeine after 4pm.
REST when you are tired. Quit feeling like a loser ( I beat myself up about this all the time0. This is a manageble disease, but not curable but flare ups are caused by, and exacerbated by, lack of rest. Every day, thru the day, ask yourself honestly what your body needs, and do it. Sometimes just lettingyourself off the hook will make you feel much better.

May 11, 2012 at 8:16 pm
(271) lucidkitty says:

continued-

The person who made the vitamin and supplement comments is 100% dead on- see a nutritionist. You have to have adequate D3, Omega 3 (Omega 6 and 9 are PRO- inflammatory so the 3:6/9 ratio should be low). See a nutritionist, preferably one who understands this illness.
Easy exercise. Walking. Swimming. Later, if you start to feel better, you can do more.

IF YOUR DRUGS DEPRESS YOU OR GIVE YOU SUICIDAL THOUGHTS CALL YOUR MD IMMEDIATELY. Best to be seeing at psychiatrist as well to help manage these meds.

Often, adding meds for a short time, or later decreasing doses, can help maintain you.

This is an illness managed from many perspectives- meds are one. And you need them.
Remember that opiates (pain relievers- especially Tramadol) can cause seretinin syndrome and worsen irritablity and restless sleep. Try altering you dosing so that it is still regular but maybe not before bed.

June 20, 2012 at 5:17 pm
(272) EBY says:

Okay…so I just took my first dosage of savella about one and a half hours ago…I am feeling a littler jittery and I feel the nausea coming on. Please pray for me. I am tired of feeling sick. Do any of you have other alternatives for fibromyalgia? Home remedies? This is really getting me depressed.

July 13, 2012 at 7:29 am
(273) Kenneth says:

One day three of the Savella titration pack and I’m feeling better than I have in quite a long time.

Now, other than momentary excessive sweating I haven’t had any negative side effects. The positive effect so far are, reduced pain, great range of motion with a lot less morning stiffness and much less stifness and paid throughout the day.

Lyrica made me crazy, cymbalta was ineffective and everything else that everyone listed did’t work either. Savella is the only thing that show any promise of positive change on my conditions.

My conditions are Sjorgren’s syndrome, Fibromyalgia, end stage arthritis in both knees and lower back. I need knee replacements and back surgery, both of which, are out of the question.

Savella so far has been the only game changer.

August 1, 2012 at 9:34 pm
(274) Maria B says:

Can anyone tell me about weight gain/loss on this drug????? I was on Cymbalta since January 2010 and it was a miracle drug for me. I have Fribromyalgia. My main symptoms were/are joint pain, fatigue like you wouldn’t believe, stiffness. With the Cymbalta I was very happy…except for the weight gain. 135 when I started, 157 when I decided ENOUGH! and got off it…but of course my symptoms came back with a vengeance. So I am trying Savella now…just took my first little blue pill from the starter pack my Doc gave me…Hopefully it will work as well as the Cymbalta did without making me gain anymore weight! I am very active too, which helps me feels great! I run daily outside or in the gym, lift weights, bike, etc. But I can’t lose any weight on the Cymbalta!! AAARRRGGGGGGG!! Please anyone let me know how the Savella has affected your weight?

August 7, 2012 at 6:05 pm
(275) windingdown says:

I use Low Dos Naltrexone (LDN) for over a year now for my firbo I cant tell you how much it has helped me.. Im not back to my old self but the longer I use it the better I feel, google the Stanford Medical school study on LDN and fibro.. take it to you Dr try LDN its better than all those other big pharma drugs.. how 3.0 mg of once aday helps me and my 81 yr old mom.. come join the support page and see how many are helped by LDN there.. THANKS!

August 7, 2012 at 6:05 pm
(276) windingdown says:

I use Low Dos Naltrexone (LDN) for over a year now for my firbo I cant tell you how much it has helped me.. Im not back to my old self but the longer I use it the better I feel, google the Stanford Medical school study on LDN and fibro.. take it to you Dr try LDN its better than all those other big pharma drugs.. how 3.0 mg of once aday helps me and my 81 yr old mom.. come join the support page and see how many are helped by LDN there.. THANKS!

August 17, 2012 at 12:33 pm
(277) Gwen Stone says:

I asked my doctor about Savella and she said that it is the only one that doesn’t make you gain weight. A friend of mine started one of the other medications and gained 20 lbs. in a month. I started taking it in April 2012 and I can actually get up out of bed in the morning without pain. I haven’t done that for years. It’s wonderful. It has made me a little more depressed though.

September 7, 2012 at 8:58 pm
(278) Tammy says:

I had a tumor removed at C2 two years ago. I was left with major nerve pain on the right side of my body (which is better than the alternative of paralysis and many other problems), however I’ve been on many different drugs to include Lyrica (which I gained a lot of weight in a short time) and am currently taking 4800mg of neurontin. yes, I said 4800mg. I can’t even begin to tell you the side effects I have. I started out this process at 107 lbs and I’m now 140 and am 40 years old. I’m desperately looking for something to make me feel better. I haven’t been myself for so long. After reading all of these comments, I am going to ask my doctor next week about Savella. It’s so sad to see how everyone suffers and most without relief.
Thanks for all of your comments.

October 4, 2012 at 11:47 am
(279) Alice says:

I started using Lyrica for my Fibromyalgia pain it gave me relief but not without drawbacks. It made me really dizzy at first then after I got use to it the pain increase and I had to take more twice daily and that is where my biggiest problem began. I started with dry mouth really bad then an increase in appetite then the swelling and rapid weight gain. I gained 25 lbs in about 5 weeks and I was in so much pain and discomfort that I didnt even realize I had gained so much so fast. I am diabetic too so that was really a big problem with my other doctor because now I had to increase my other meds and I been on a roller coaster ride. So a word to the wise be careful taking this medication the side effects have a big kicker.

November 2, 2012 at 9:00 pm
(280) Lauren says:

I have chronic back pain after a long 3 month fight with meningitis. I had a bad spinal tap that left a large leak of fluid and blood around my spine. Since recovering I have pain all day and everyday. I tried Cymbalta during the my illness to help my with my tingling throughout my body. It really helped but it made me sweat like a pig and then i started hearing voices. That experience was crazy and has left me very afraid of taking anti-depressants. My Neurologist wants me to try Savella but I am afraid. She also thinks that the meningitis has left me with fibro. Has anyone heard of meningitis causing fibro?? I am 21 years old and I spent 2 weeks in the hospital during my illness. The first doctor sent me home with oxicoton and oxycodone and those helped a little. The second hospital stay the doctor released me with Ms contin and oxycode. Ms contin made living with pain so much easier because when I was on it I HAD NONE. I have had a hard time with pain doctors. They all think I am lying and I just want drugs. It makes me feel awful and being young doesn’t help. Do I have a lifetime of pain and suffering ahead of me?? Would love some feedback.

Hugs to all

December 7, 2012 at 12:10 pm
(281) maryg says:

Just to add some comments about Savella.
I participated in the clinical trials for the drug and could tell when I was give a placebo. I would immecdiately begin to feel worse.
So I have been using this drug since at least 2008 and have no side effects I can attribute to Savella. I have tapered down a couple of times but went right back to full force because I immediately began to feel worse. I tried Lyrica way back when and it just made me loopy. (My neurologist wanted to prescribe it for neuropathy but I refused -told him that adding other drugs with savella did not seem like a good idea to me.
I take a bunch of drugs in the morning and if I do not eat a little something I will be slightly nauseated until I do eat. Generally have a breakfast bar before taking the pills.
I just wanted to let those who read this know that not all people will have adverse reactions.
The expense of the drug worries me because retirement iis near and my three months supply from mail order is about $800 now. Geez. It’s enough to make you sicker than you already are!

December 13, 2012 at 1:06 pm
(282) Cvz5 says:

In regards to Lauren from November 2, 2012 comment. My Rhrm MD told me when I was diagnosed with fibro that it could be brought on during or because of an incident that are triggering factors due to the mental & physical stressors. Lookup article at , “American College of Rheumatology”, http://www.rheumatology.org look for what causes fibromyalgia. I like your closing but, sadly Hugs hurt too!

December 26, 2012 at 9:21 pm
(283) kasebria says:

in response to (281) maryg – I would think that a generic should be around the corner – although some recent drugs to get a “generic” have been created by a subsidiary of their original mgf and thus not really giving a generic price – very frustrating….

Savella is the FIRST drug I have used since getting sick in 1994 that didn’t cloud my brain – I actually feel like ME with this medicine.

I have tried all the others and then some with no improvement only to be left feeling in a bubble, not so with this one.

I too had nausea until my body got used to it – but well worth it. No weight gain with this one for me.

Here’s to hoping for a decently priced generic (that works) soon!

~ K

December 27, 2012 at 9:05 pm
(284) Julie says:

I’ve been on Savella for a few months and it has helped my Fibro very much. I’ve had little to no side effects thus far but lately I’ve been having nausea just about all day and my vision has become blurry. Could Savella be causing these symptoms?

January 25, 2013 at 1:58 am
(285) Windingdown says:

I hope everybody who’s reading these comments will Google LDN and fibromyalgia. There a lot of clinical trials also Stanford medical school had 2 studies done on low dose Naltrexone also known as LDN … I take it myself for nearly 2 years. Anywhere from 1.0 mg to 4.5 mg before bed. Very low-dose as stated, fibromyalgia and chronic fatigue patients usually take 3.0 as we do the sensitivity of medications ….. I myself am very happy with the results also I upped my magnesium level by taking supplements every day which helped my muscle pain but the LDN definitely helped my joint pain a lot I also suffer from arthritis in both knees and help the pain of my arthritis as well. I no longer take handfuls of OTC Pain meds or opiates. Once I found out that opiates actually ruin your immune system I was determined to find an Alternative. The beauty of LDN it modulates balances your immune system while you take it. Please Google LDN read as much as you can on it, LDN treats anything from cancer to autoimmune it tricks your body into healing
itself. Try googling that LDN tricks your body into healing itself. It’s not the LDN it’s how your body reacts to the LDN that makes the difference

February 7, 2013 at 1:31 am
(286) Hank Wayman says:

Having read about 50 comments I think I will comment. I am almost 72 yrs old and have been dealing with overall body pain for about 20 yrs. I have tried all the meds mentioned at one time or another. About 12 yrs ago my Dr prescribed Morphine, my pain was so bad at that time I said ok. BIG MISTAKE!! here I am 12 yrs later going through terrible withdrawals with all its pain, sniffing nose, sweats, chills and muscle spazims. I also take ambien to get me to sleep yet here I am much after my bedtime writing a comment to this . I am also starting Lyrica to replace the morphine. No pain relief yet. I go to my doctor tomorrow and maybe he will get me into a treatment center to get me the rest of the way out of here. I read about the Savella and will ask doctor what he thinks tomorrow. I guess thats all I get to comment, God Bless all who ge this way.

April 27, 2013 at 3:02 am
(287) Caregiver says:

You folks might price Canada Drug stores for generic Savella (.84 ea.) at several. My insurance copay is $34 monthly for up to 120 tablets. Also there is some 75% discount coupons also available online!

May 16, 2013 at 2:27 pm
(288) Leslie says:

I am worried that the FDA is not really monitoring this drug and what it is doing to patients. I know doctors aren’t documenting or reporting adverse reactions. They just want the patient to try another drug. Maybe the drug companies president, vice president, etc. should try it out for themselves for a few years and see how they feel. How bout it guys?

May 17, 2013 at 6:45 am
(289) Britnee Marie says:

Does anyone know if savella causes hot flashes continuous sweating itching or tingling throughout your head side of your face and threw ur enire body and also my skin seems to be very sensitive to heat and or sunlight… can someone please tell me if these are just part of my fibro or is it the savella?

May 20, 2013 at 12:59 pm
(290) Visit Website says:

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October 28, 2013 at 9:57 pm
(291) adelaida says:

I want to know, If any one has notice after taking savella if you vision has change? I use glasses and suddenly I notice that in just 2 months that I have used the medicine my vision get worse

January 13, 2014 at 9:56 pm
(292) Casey says:

Hi, I have been on Savella for 2 years now, for my fibromyalgia, and it has done great for me. Without it, it is hard to function, I have Fibromyalgia very badly, but with it I can now work, and most of all spend more time having fun with my 4 kids. I have not gained weight since I started taking it 2 years ago. I do take it twice a day, what is prescribed to me, but I do feel nausea due to it, so when I take it first I take a nausea pill then wait 5 min then take it. I believe it is worth it though and am very happy with it. :)

February 18, 2014 at 11:35 pm
(293) Maria says:

just started Savella today, sure hope it works for me.

March 3, 2014 at 12:06 am
(294) db says:

I was on Cymbalta for my FM. It was a true God-send!!!! Finally -relief. I had been on it for two years and sad to say had to go off because of side effects. I sweat like crazy and did begin to itch near the end. it was FANTASTIC for my depression. I had been on Zoloft for many years which did a good job for depression but not for FM.
Since I had to go off the Cymbalta (sad) the Dr. put me on Prozac. OMG. I know people that do well on it but I turned into a b-atch!!! Horrible for me. So went back on Zoloft. It dies the job but Cymbalta did more for me.
I do take vit.D but need to check out the magnesium, B12 and i thin should check my iron as well as I had a bit of a problem a few years ago and actually had to have an infusion.
I did gain weight on the Cymbalta-yuck. I need some pain relief for FM
!

March 3, 2014 at 12:09 am
(295) db says:

Has anyone tried Gabapentin?

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