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By Carol & Richard Eustice, About.com Guides to Arthritis since 1997

Fibromyalgia Symptoms Associated With Hippocampus Dysfunction

Saturday August 30, 2008
Fibromyalgia symptoms can mimic or overlap symptoms associated with other rheumatic diseases. Muscular pain, fatigue, headaches, sleep problems, memory problems, noise sensitivity, and depression are just some of the symptoms associated with fibromyalgia. According to a study published in the July 2008 issue of the Journal of Rheumatology researchers have suggested that hippocampus dysfunction may explain some fibromyalgia symptoms.

The study assessed 15 female patients, who met criteria for classification of fibromyalgia, and compared them to 10 healthy females for N-acetylaspartate (NAA), choline, creatine, and their ratios from both hippocampi. Results showed that the hippocampus was dysfunctional in fibromyalgia patients -- primarily demonstrated by lower NAA levels compared to the healthy women. The hippocampus is a part of the brain and functions in the maintenance of cognitive functions, sleep regulation, and pain perception. The findings are considered another piece to what's considered a puzzling medical condition.

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