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By Carol & Richard Eustice, About.com Guides to Arthritis since 1997

Certain Arthritis Medicines May Cause Photosensitivity

Saturday June 23, 2007
Photosensitivity can be a side effect of certain arthritis medications. Photosensitivity is a skin reaction that occurs after exposure to ultraviolet (UV) radiation from the sun or an artificial light source. It's estimated that 1 in 100 people show some signs of photosensitivity. Reactions can be phototoxic or photoallergic.

Phototoxic reactions account for 95 percent of all cases of photosensitivity. Phototoxic reactions occur as a result of ingesting certain medications, and their incidence and severity have been directly linked to the drug dosage and amount of UV exposure.

Photoallergic reactions are caused by the reaction of a topical ointment with the sun. Photoallergic reactions may develop after 1 to 10 days of exposure, but will often re-occur within 24 to 48 hours of re-exposure. In a photoallergic reaction, the drug or ointment, which also includes cosmetic creams and sunscreens, absorbs the UV energy and binds to the protein in the skin, causing an allergic rash.

How do certain medications react with the sun? Which medications are associated with reactions? What measures can you take to prevent sun sensitivity reactions? Read more in Sun Sensitivity Can Be Side Effect of Certain Medications.

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