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Carol Eustice

Green Tea Compound May Benefit Rheumatoid Arthritis

By , About.com Guide   May 1, 2007

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green teaA compound in green tea may offer therapeutic benefit to people with rheumatoid arthritis. According to a study reported April 30th, from the University of Michigan Health System, a green tea compound known as epigallocatechin-3-gallate (EGCG) was found to inhibit production of several molecules associated with inflammation and joint damage in rheumatoid arthritis patients.

Researchers isolated synovial fibroblasts (cells that form a lining of tissue which surrounds the joint capsule) from the joints of rheumatoid arthritis patients in order to conduct the study. The synovial fibroblasts were cultured in a growth medium and incubated with the green tea compound. The fibroblasts were then stimulated with an immune system protein known to play a significant role in joint destruction.

Researchers found that the green tea compound inhibited pathways which caused inflammation and bone destruction. The promising results make a good case for future testing of the green tea compound in animal models of rheumatoid arthritis and eventually humans with rheumatoid arthritis.

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