It is well-known that cartilage is composed of interlocking collagen fibers which give it structure and strength. The exact structure of the fibers however, also referred to as fibrils, has remained elusive for decades. Using electron microscopic techniques, researchers from the University of Manchester have discovered the molecular structure of the thinner of two types of collagen fibrils. The findings are considered important to determining what occurs at the molecular level as osteoarthritis develops.
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