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By Carol & Richard Eustice, About.com Guides to Arthritis since 1997

Levitra - Vardenafil - Dosage - Side Effects - Drug Interactions - Warnings

Tuesday April 18, 2006
Levitra (vardenafil) drug information, dosage, side effects, drug interactions, and warnings. Levitra, generic drug name vardenafil, is a selective phosphodiesterase (PDE) type 5 inhibitor. Levitra, approved for male erectile dysfunction treatment, may also improve circulation in other medical conditions.

Levitra Reduces Symptoms Associated With Raynaud's Disease

Levitra (vardenafil) significantly decreased the duration, frequency, and severity of Raynaud's disease attacks in an open-label pilot study. The research was led by Dr. Evren Caglayan at the University of Köln, Germany.

According to Rheumatology News, the researchers tested vardenafil in 40 patients with Raynaud's disease (3 men and 37 women). Of these patients, 7 had primary Raynaud's disease, and 33 had Raynaud's secondary to connective tissue disease. The patients took 10 mg of vardenafil twice daily for 2 weeks.

  • 27 patients (68%) reported concomitant improvement in clinical symptoms (noting that the duration, frequency, and severity of Raynaud attacks each decreased significantly with treatment).
  • Most of the patients with secondary Raynaud's disease (64%) responded well to Levitra (vardenafil).
  • Six of the seven patients (86%) with primary Raynaud's disease responded well.

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