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By Carol & Richard Eustice, About.com Guides to Arthritis since 1997

Mirapex: Fibromyalgia Pain Relieved by Pramipexole

Friday July 29, 2005
A study of 60 fibromyalgia patients who randomly received gradually increasing doses of Mirapex (pramipexole), a commonly prescribed medication for Parkinson's disease, or placebo showed promising results. According to the report in the August issue of Arthritis & Rheumatism:

  • 42 percent of patients taking Mirapex had a 50 percent or more decrease in pain vs. 14 percent of the placebo group.
  • 82 percent of patients taking Mirapex had "some improvement" in pain vs. 57 percent of the placebo group.

Study participants who recevied Mirapex (pramipexole) also showed improvement in fatigue and function. Mirapex (pramipexole) is classified as a dopamine receptor agonist and has also been studied as a treatment for Restless Legs Syndrome.

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Comments

June 24, 2006 at 12:41 am
(1) Martha Brimhalll says:

I am in the process of weaning my self off of Mirapex, I can tell you that for fibromyalgia it really helps. Ive also noticed that since I have been weaning my self off of mirapex My restless leg syd.
has gotten real bad , also muscle spasms
and the usual aches and pains.

August 28, 2006 at 11:36 pm
(2) Linda says:

Could I ask why you are weaning yourself off mirapex if it helped you? Were the side effects really bad? Just wondering. I want to try Mirapex.

September 13, 2006 at 4:33 pm
(3) Margie says:

I have had Fibromyalgia for over 12 years with debilitating pain and muscle knots all over my body. I could hardly walk in the grocery store. I was using a cain to get around and had to have help getting up and down. I didn’t sleep well at all from the pain.
Every doctor I went to said there was no treatment for this.
Last month I went to a Rheumatolgist who prescribed Mirapex. In only one month my pain is nearly gone. I am walking on my own and sleeping well every night.

February 1, 2009 at 7:58 am
(4) sue says:

My husband has fibro, he’s had it for more than 8 years he has horrible pain everywhere all the time..legs,arms,back, abdomin,jaw,throat,head,eyes.. I can’t even begin to mention the things we’ve tried. We live in Canada and here medical care is useless for such a disease. He hasn’t tried Mirapex yet, but the fight or flight theory sounds right to him, he had traumatic experience at age 17 and the pain persisted in a a specific area after surgery, But after around 10 years started to appear everywhere else. What I would like to know is how many people out there have used Mirapex for a post traumatic fibromyalgia success or not.

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